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Crystal structure of the PPARgamma-LBD complexed with compound 13ab
Descriptor:	3-{[6-(4-chloro-3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoic acid, CHLORIDE ION, Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, ...
Authors:	Matsui, Y, Hanzawa, H.
Deposit date:	2018-01-19
Release date:	2018-10-17
Last modified:	2023-11-22
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Discovery of DS-6930, a potent selective PPAR gamma modulator. Part I: Lead identification. Bioorg. Med. Chem., 26, 2018

Crystal structure of the PPARgamma-LBD complexed with compound DS-6930
Descriptor:	3-[[6-(3,5-dimethylpyridin-2-yl)oxy-1-methyl-benzimidazol-2-yl]methoxy]benzoic acid, CHLORIDE ION, Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, ...
Authors:	Matsui, Y, Hanzawa, H.
Deposit date:	2018-01-25
Release date:	2018-10-17
Last modified:	2023-11-22
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Discovery of DS-6930, a potent selective PPAR gamma modulator. Part II: Lead optimization. Bioorg. Med. Chem., 26, 2018

THE STRUCTURE AT 1.8 ANGSTROMS RESOLUTION OF A SINGLE SITE MUTANT (T189I) OF MALATE DEHYDROGENASE FROM THERMUS FLAVUS WITH INCREASED ENZYMATIC ACTIVITY
Descriptor:	BETA-6-HYDROXY-1,4,5,6-TETRHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MALATE DEHYDROGENASE
Authors:	Kelly, C.A, Birktoft, J.J.
Deposit date:	1993-02-16
Release date:	1994-12-20
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Determinants of protein thermostability observed in the 1.9-A crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus. Biochemistry, 32, 1993