Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
8PVT
DownloadVisualize
BU of 8pvt by Molmil
Manganese-dependent transcriptional repressor DR2539 complexed with cadmium (SAD 7 keV)
Descriptor: CADMIUM ION, Iron dependent repressor, putative
Authors:Mota, C, De Sanctis, D.
Deposit date:2023-07-18
Release date:2024-05-08
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Metal ion activation and DNA recognition by the Deinococcus radiodurans manganese sensor DR2539.
Febs J., 291, 2024
8PO2
DownloadVisualize
BU of 8po2 by Molmil
Discovery and Optimisation of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations. Compound 33 bound to EGFRinsNPG [V948R]
Descriptor: 1-cyclopropyl-~{N}-[3-[1-(1-propanoylazetidin-3-yl)-4-pyridin-4-yl-pyrazol-3-yl]phenyl]imidazole-4-carboxamide, Epidermal growth factor receptor
Authors:Hargreaves, D.
Deposit date:2023-07-03
Release date:2024-06-05
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations.
J.Med.Chem., 67, 2024
8PTI
DownloadVisualize
BU of 8pti by Molmil
CRYSTAL STRUCTURE OF A Y35G MUTANT OF BOVINE PANCREATIC TRYPSIN INHIBITOR
Descriptor: BOVINE PANCREATIC TRYPSIN INHIBITOR
Authors:Housset, D, Kim, K.-S, Fuchs, J, Woodward, C, Wlodawer, A.
Deposit date:1990-12-17
Release date:1991-04-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a Y35G mutant of bovine pancreatic trypsin inhibitor.
J.Mol.Biol., 220, 1991
8PO0
DownloadVisualize
BU of 8po0 by Molmil
Discovery and Optimisation of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations. Compound 12 bound to EGFRinsNPG
Descriptor: 1-[3-[7-methoxy-4-[3-(3-methoxyphenyl)-1~{H}-pyrazol-4-yl]quinazolin-6-yl]oxyazetidin-1-yl]propan-1-one, Epidermal growth factor receptor
Authors:Hargreaves, D.
Deposit date:2023-07-03
Release date:2024-06-05
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.523 Å)
Cite:Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations.
J.Med.Chem., 67, 2024
8PQX
DownloadVisualize
BU of 8pqx by Molmil
p97 (VCP) mutant - F539A state III
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Transitional endoplasmic reticulum ATPase
Authors:Arie, M, Matzov, D, Karmona, R, Szenkier, N, Stanhill, A, Navon, A.
Deposit date:2023-07-12
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:p97 (VCP) mutant - F539A state III
To Be Published
7BOM
DownloadVisualize
BU of 7bom by Molmil
Crystal structure of recombinant horse spleen apo-R52C/E56C/R59C/E63C-Fr immobilized with gold ions.
Descriptor: 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ...
Authors:Hishikawa, Y, Maity, B, Ito, N, Abe, S, Lu, D, Ueno, T.
Deposit date:2020-03-19
Release date:2021-01-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Design of Multinuclear Gold Binding Site at the Two-fold Symmetric Interface of the Ferritin Cage
Chem Lett., 49, 2021
8D04
DownloadVisualize
BU of 8d04 by Molmil
Hallucinated C2 protein assembly HALC2_062
Descriptor: HALC2_062
Authors:Ragotte, R.J, Bera, A.K, Wicky, B.I.M, Milles, L.F, Baker, D.
Deposit date:2022-05-25
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Hallucinating symmetric protein assemblies.
Science, 378, 2022
8D07
DownloadVisualize
BU of 8d07 by Molmil
Hallucinated C3 protein assembly HALC3_109
Descriptor: HALC3_109
Authors:Ragotte, R.J, Bera, A.K, Wicky, B.I.M, Milles, L.F, Baker, D.
Deposit date:2022-05-25
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Hallucinating symmetric protein assemblies.
Science, 378, 2022
7BX7
DownloadVisualize
BU of 7bx7 by Molmil
Cryo-EM structure of amyloid fibril formed by hnRNPA1 low complexity domain
Descriptor: Heterogeneous nuclear ribonucleoprotein A1
Authors:Sun, Y.P, Zhao, K, Liu, C, Li, D.
Deposit date:2020-04-17
Release date:2020-11-18
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:The nuclear localization sequence mediates hnRNPA1 amyloid fibril formation revealed by cryoEM structure.
Nat Commun, 11, 2020
8D05
DownloadVisualize
BU of 8d05 by Molmil
Hallucinated C2 protein assembly HALC2_065
Descriptor: HALC2_065
Authors:Ragotte, R.J, Bera, A.K, Wicky, B.I.M, Milles, L.F, Baker, D.
Deposit date:2022-05-25
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Hallucinating symmetric protein assemblies.
Science, 378, 2022
8PO3
DownloadVisualize
BU of 8po3 by Molmil
Discovery and Optimisation of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations. Compound 18 bound to EGFR[V948R]
Descriptor: 2-methyl-5-[[3-[1-[(3~{S})-1-propanoylpyrrolidin-3-yl]-4-pyridin-4-yl-pyrazol-3-yl]phenoxy]methyl]-3~{H}-isoindol-1-one, Epidermal growth factor receptor
Authors:Hargreaves, D.
Deposit date:2023-07-03
Release date:2024-06-05
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations.
J.Med.Chem., 67, 2024
8PO1
DownloadVisualize
BU of 8po1 by Molmil
Discovery and Optimisation of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations. Compound 22 bound to EGFRinsNPG [V948R]
Descriptor: 2-methyl-5-[[3-[1-[(3~{S},5~{R})-5-methyl-1-propanoyl-pyrrolidin-3-yl]-4-pyridin-4-yl-pyrazol-3-yl]phenoxy]methyl]-3~{H}-isoindol-1-one, Epidermal growth factor receptor, IODIDE ION
Authors:Hargreaves, D.
Deposit date:2023-07-03
Release date:2024-06-05
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations.
J.Med.Chem., 67, 2024
8PO4
DownloadVisualize
BU of 8po4 by Molmil
Discovery and Optimisation of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations. Compound 33 bound to EGFR[V948R]
Descriptor: 1-cyclopropyl-~{N}-[3-[1-(1-propanoylazetidin-3-yl)-4-pyridin-4-yl-pyrazol-3-yl]phenyl]imidazole-4-carboxamide, ADENOSINE-5'-TRIPHOSPHATE, Epidermal growth factor receptor, ...
Authors:Hargreaves, D.
Deposit date:2023-07-03
Release date:2024-06-05
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.621 Å)
Cite:Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations.
J.Med.Chem., 67, 2024
7C1L
DownloadVisualize
BU of 7c1l by Molmil
Crystal structure of the starter condensation domain of rhizomide synthetase RzmA mutant R148A in complex with C8-CoA
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Non-ribosomal peptide synthetase modules, OCTANOYL-COENZYME A
Authors:Zhong, L, Diao, X, Zhang, N, Li, F.W, Zhou, H.B, Chen, H.N, Ren, X, Zhang, Y, Wu, D, Bian, X.
Deposit date:2020-05-05
Release date:2020-11-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis.
Nat Commun, 12, 2021
8D08
DownloadVisualize
BU of 8d08 by Molmil
Hallucinated C4 protein assembly HALC4_135
Descriptor: HALC4_135
Authors:Ragotte, R.J, Bera, A.K, Wicky, B.I.M, Milles, L.F, Baker, D.
Deposit date:2022-05-25
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Hallucinating symmetric protein assemblies.
Science, 378, 2022
7C1U
DownloadVisualize
BU of 7c1u by Molmil
Crystal structure of the starter condensation domain of rhizomide synthetase RzmA mutant H140V/R148A in a "product-released" conformation
Descriptor: Non-ribosomal peptide synthetase modules
Authors:Zhong, L, Diao, X, Zhang, N, Li, F.W, Zhou, H.B, Chen, H.N, Ren, X, Zhang, Y, Wu, D, Bian, X.
Deposit date:2020-05-05
Release date:2020-11-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis.
Nat Commun, 12, 2021
8PEW
DownloadVisualize
BU of 8pew by Molmil
Rho-ATPgS-Psu complex II
Descriptor: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Polarity suppression protein, ...
Authors:Gjorgjevikj, D, Wahl, M.C, Hilal, T, Loll, B.
Deposit date:2023-06-15
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Rho-ATPgS-Psu complex II
To Be Published
8PNZ
DownloadVisualize
BU of 8pnz by Molmil
Discovery and Optimisation of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations. Compound 16 bound to EGFR
Descriptor: 1-[(3~{S})-3-[4-(6,7-dimethoxyquinazolin-4-yl)-3-(3-methoxyphenyl)pyrazol-1-yl]pyrrolidin-1-yl]propan-1-one, Epidermal growth factor receptor
Authors:Hargreaves, D.
Deposit date:2023-07-03
Release date:2024-06-05
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations.
J.Med.Chem., 67, 2024
8PEL
DownloadVisualize
BU of 8pel by Molmil
Structure of C. thermophilum RNA exosome core
Descriptor: Exoribonuclease phosphorolytic domain-containing protein, Exoribonuclease-like protein, Exosome complex component MTR3, ...
Authors:Lazzaretti, D, Holdermann, I, Sprangers, R.
Deposit date:2023-06-14
Release date:2024-06-26
Method:X-RAY DIFFRACTION (3.81 Å)
Cite:Beyond static structures: quantitative dynamics in the eukaryotic RNA exosome complex
Biorxiv, 2024
8D03
DownloadVisualize
BU of 8d03 by Molmil
Hallucinated C2 protein assembly HALC2_068
Descriptor: HALC2_068
Authors:Ragotte, R.J, Bera, A.K, Wicky, B.I.M, Milles, L.F, Baker, D.
Deposit date:2022-05-25
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Hallucinating symmetric protein assemblies.
Science, 378, 2022
8D09
DownloadVisualize
BU of 8d09 by Molmil
Hallucinated C4 protein assembly HALC4_136
Descriptor: HALC4_136
Authors:Ragotte, R.J, Bera, A.K, Wicky, B.I.M, Milles, L.F, Baker, D.
Deposit date:2022-05-25
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Hallucinating symmetric protein assemblies.
Science, 378, 2022
8PFR
DownloadVisualize
BU of 8pfr by Molmil
Mouse RPL39L integrated into the yeast 60S ribosomal subunit
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Rabl, J, Banerjee, A, Boehringer, D, Zavolan, M.
Deposit date:2023-06-16
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (2.15 Å)
Cite:Mouse RPL39L integrated into the yeast 60S ribosomal subunit
To Be Published
8D06
DownloadVisualize
BU of 8d06 by Molmil
Hallucinated C3 protein assembly HALC3_104
Descriptor: HALC3_104
Authors:Ragotte, R.J, Bera, A.K, Wicky, B.I.M, Milles, L.F, Baker, D.
Deposit date:2022-05-25
Release date:2022-09-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Hallucinating symmetric protein assemblies.
Science, 378, 2022
8PEX
DownloadVisualize
BU of 8pex by Molmil
Rho P167L-ATPgS-Psu complex I
Descriptor: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Polarity suppression protein, ...
Authors:Gjorgjevikj, D, Wahl, M.C, Hilal, T, Loll, B.
Deposit date:2023-06-15
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Rho P167L-ATPgS-Psu complex I
To Be Published
8PEU
DownloadVisualize
BU of 8peu by Molmil
Rho-ATPgS-Psu complex I
Descriptor: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Polarity suppression protein, ...
Authors:Gjorgjevikj, D, Wahl, M.C, Hilal, T, Loll, B.
Deposit date:2023-06-15
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Rho-ATPgS-Psu complex I
To Be Published

224004

数据于2024-08-21公开中

PDB statisticsPDBj update infoContact PDBjnumon