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6B6A
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BU of 6b6a by Molmil
Beta-Lactamase, 2secs timepoint, mixed, shards crystal form
Descriptor: (2R)-2-[(1S)-1-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-2-hydroxyethyl]-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase, Ceftriaxone, ...
Authors:Pandey, S, Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B6C
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BU of 6b6c by Molmil
Beta-Lactamase, mixed with Ceftriaxone, needles crystal form, 30ms
Descriptor: Beta-lactamase, Ceftriaxone
Authors:Pandey, S, Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B6B
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BU of 6b6b by Molmil
Beta-Lactamase, unmixed needles crystal form
Descriptor: Beta-lactamase
Authors:Pandey, S, Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B6E
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BU of 6b6e by Molmil
Beta-Lactamase, mixed with Ceftriaxone, needles crystal form, 500ms
Descriptor: (2R)-2-[(1S)-1-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-2-hydroxyethyl]-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase, Ceftriaxone
Authors:Pandey, S, Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6B68
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BU of 6b68 by Molmil
Beta-Lactamase, 100ms timepoint, mixed, shards crystal form
Descriptor: (2R)-2-[(1S)-1-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-2-hydroxyethyl]-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase, Ceftriaxone, ...
Authors:Pandey, S, Schmidt, M.
Deposit date:2017-10-01
Release date:2018-06-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
BMC Biol., 16, 2018
6E5G
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BU of 6e5g by Molmil
Crystal structure of human TEAD2-Yap binding domain covalently bound to an allosteric regulator
Descriptor: 1-(2-{[3-(trifluoromethyl)phenyl]amino}phenyl)ethan-1-one, Transcriptional enhancer factor TEF-4
Authors:Bum-Erdene, K, Gonzalez-Gutierrez, G, Meroueh, S.O.
Deposit date:2018-07-20
Release date:2019-01-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein Interaction.
Cell Chem Biol, 26, 2019
6VY1
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BU of 6vy1 by Molmil
Cryo-EM structure of filamentous PFD from Methanocaldococcus jannaschii
Descriptor: Prefoldin subunit alpha 2
Authors:Wang, F, Chen, Y.X, Ing, N.L, Hochbaum, A.I, Clark, D.S, Glover, D.J, Egelman, E.H.
Deposit date:2020-02-25
Release date:2020-05-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structural Determination of a Filamentous Chaperone to Fabricate Electronically Conductive Metalloprotein Nanowires.
Acs Nano, 14, 2020
7YOX
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BU of 7yox by Molmil
Cryo-EM structure of the N-terminal domain of hMCM8/9 and HROB
Descriptor: DNA helicase MCM8, DNA helicase MCM9
Authors:Zheng, J.F, Weng, Z.F, Liu, Y.F.
Deposit date:2022-08-02
Release date:2023-08-09
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structural and mechanistic insights into the MCM8/9 helicase complex.
Elife, 12, 2023
6NII
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BU of 6nii by Molmil
Crystal structure of RavD (residues 1-200) from Legionella pneumophila (strain Corby)
Descriptor: Uncharacterized protein RavD
Authors:Wang, X, Zhou, Y, Zhu, Y.
Deposit date:2018-12-28
Release date:2019-05-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A bacterial effector deubiquitinase specifically hydrolyses linear ubiquitin chains to inhibit host inflammatory signalling.
Nat Microbiol, 4, 2019
6N9P
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BU of 6n9p by Molmil
Discovery of affinity-based probes for Btk occupancy assay
Descriptor: N-(3-{[2-amino-3-(4-phenoxyphenyl)pyridin-4-yl]oxy}phenyl)propanamide, Tyrosine-protein kinase BTK
Authors:Mochalkin, I.
Deposit date:2018-12-03
Release date:2019-02-06
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Discovery of Affinity-Based Probes for Btk Occupancy Assays.
ChemMedChem, 14, 2019
6NJD
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BU of 6njd by Molmil
Crystal structure of RavD (residues 1-200) from Legionella pneumophila (strain Corby) complexed with Met-1 linked di-ubiquitin
Descriptor: Di-ubiquitin, MAGNESIUM ION, RavD
Authors:Wang, X, Zhou, Y, Zhu, Y.
Deposit date:2019-01-03
Release date:2019-05-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A bacterial effector deubiquitinase specifically hydrolyses linear ubiquitin chains to inhibit host inflammatory signalling.
Nat Microbiol, 4, 2019
3D7Q
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BU of 3d7q by Molmil
Crystal structure of a xisi-like protein (npun_ar114) from nostoc punctiforme pcc 73102 at 2.30 A resolution
Descriptor: XisI protein-like
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2008-05-21
Release date:2008-06-17
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Site-specific recombination of nitrogen-fixation genes in cyanobacteria by XisF-XisH-XisI complex: Structures and models.
Proteins, 2014
2INB
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BU of 2inb by Molmil
Crystal structure of an XisH family protein (ZP_00107633.1) from Nostoc punctiforme PCC 73102 at 1.60 A resolution
Descriptor: CHLORIDE ION, GLYCEROL, hypothetical protein
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2006-10-06
Release date:2006-10-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Site-specific recombination of nitrogen-fixation genes in cyanobacteria by XisF-XisH-XisI complex: Structures and models.
Proteins, 2014
2HFD
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BU of 2hfd by Molmil
NMR structure of protein Hydrogenase-1 operon protein hyaE from Escherichia coli: Northeast Structural Genomics Consortium Target ER415
Descriptor: Hydrogenase-1 operon protein hyaE
Authors:Singarapu, K.K, Liu, G, Eletsky, A, Parish, D, Atreya, H.S, Xu, D, Janjua, H, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2006-06-23
Release date:2006-08-22
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Protein chaperones Q8ZP25_SALTY from Salmonella typhimurium and HYAE_ECOLI from Escherichia coli exhibit thioredoxin-like structures despite lack of canonical thioredoxin active site sequence motif.
J.STRUCT.FUNCT.GENOM., 9, 2008
7JLT
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BU of 7jlt by Molmil
Crystal Structure of SARS-CoV-2 NSP7-NSP8 complex.
Descriptor: Non-structural protein 7, Non-structural protein 8
Authors:Biswal, M, Hai, R, Song, J.
Deposit date:2020-07-30
Release date:2020-08-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Two conserved oligomer interfaces of NSP7 and NSP8 underpin the dynamic assembly of SARS-CoV-2 RdRP.
Nucleic Acids Res., 49, 2021
1XN6
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BU of 1xn6 by Molmil
Solution Structure of Northeast Structural Genomics Target Protein BcR68 encoded in gene Q816V6 of B. cereus
Descriptor: hypothetical protein BC4709
Authors:Liu, G, Acton, T, Parish, D, Ma, L, Xu, D, Xiao, R, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2004-10-04
Release date:2004-12-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR data collection and analysis protocol for high-throughput protein structure determination.
Proc.Natl.Acad.Sci.Usa, 102, 2005
5WQ7
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BU of 5wq7 by Molmil
CryoEM structure of type II secretion system secretin GspD in E.coli K12
Descriptor: Putative type II secretion system protein D
Authors:Yan, Z, Yin, M, Li, X.
Deposit date:2016-11-23
Release date:2016-12-28
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structural insights into the secretin translocation channel in the type II secretion system
Nat. Struct. Mol. Biol., 24, 2017
5WQ9
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BU of 5wq9 by Molmil
CryoEM structure of type II secretion system secretin GspD G453A mutant in Vibrio cholerae
Descriptor: Type II secretion system protein D
Authors:Yan, Z, Yin, M, Li, X.
Deposit date:2016-11-23
Release date:2016-12-28
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.22 Å)
Cite:Structural insights into the secretin translocation channel in the type II secretion system
Nat. Struct. Mol. Biol., 24, 2017
5WQ4
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BU of 5wq4 by Molmil
Crystal structure of OPTN and linear diubiquitin complex
Descriptor: Optineurin, ubiquitin
Authors:Li, F, Pan, L.
Deposit date:2016-11-23
Release date:2017-12-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation.
Autophagy, 14, 2018
5WQ8
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BU of 5wq8 by Molmil
CryoEM structure of type II secretion system secretin GspD in Vibrio cholerae
Descriptor: Type II secretion system protein D
Authors:Yan, Z, Yin, M, Li, X.
Deposit date:2016-11-23
Release date:2016-12-28
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structural insights into the secretin translocation channel in the type II secretion system
Nat. Struct. Mol. Biol., 24, 2017
4G6H
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BU of 4g6h by Molmil
Crystal structure of NDH with NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ...
Authors:Li, W, Feng, Y, Ge, J, Yang, M.
Deposit date:2012-07-19
Release date:2012-10-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.262 Å)
Cite:Structural insight into the type-II mitochondrial NADH dehydrogenases.
Nature, 491, 2012
4FZ7
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BU of 4fz7 by Molmil
Crystal structure of spleen tyrosine kinase complexed with 6-((1R,2S)-2-Amino-cyclohexylamino)-4-(6-ethyl-pyridin-2-ylamino)-pyridazine-3-carboxylic acid amide
Descriptor: 6-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(6-ethylpyridin-2-yl)amino]pyridazine-3-carboxamide, Tyrosine-protein kinase SYK
Authors:Kuglstatter, A, Slade, M.
Deposit date:2012-07-06
Release date:2013-07-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Using ovality to predict nonmutagenic, orally efficacious pyridazine amides as cell specific spleen tyrosine kinase inhibitors.
J. Med. Chem., 57, 2014
4G6G
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BU of 4g6g by Molmil
Crystal structure of NDH with TRT
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, FRAGMENT OF TRITON X-100, MAGNESIUM ION, ...
Authors:Li, W, Feng, Y, Ge, J, Yang, M.
Deposit date:2012-07-19
Release date:2012-10-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural insight into the type-II mitochondrial NADH dehydrogenases.
Nature, 491, 2012
4G74
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BU of 4g74 by Molmil
Crystal structure of NDH with Quinone
Descriptor: 2,3-DIMETHOXY-5-METHYL-6-(3,11,15,19-TETRAMETHYL-EICOSA-2,6,10,14,18-PENTAENYL)-[1,4]BENZOQUINONE, FLAVIN-ADENINE DINUCLEOTIDE, FRAGMENT OF TRITON X-100, ...
Authors:Li, W, Feng, Y, Ge, J, Yang, M.
Deposit date:2012-07-19
Release date:2012-10-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural insight into the type-II mitochondrial NADH dehydrogenases.
Nature, 491, 2012
7PT0
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BU of 7pt0 by Molmil
SCO3201 with putative ligand
Descriptor: SPERMIDINE, TetR family transcriptional regulator
Authors:Werten, S, Palm, G.J, Hinrichs, W.
Deposit date:2021-09-25
Release date:2021-10-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal structures of free and ligand-bound forms of the TetR/AcrR-like regulator SCO3201 from Streptomyces coelicolor suggest a novel allosteric mechanism.
Febs J., 290, 2023

227111

数据于2024-11-06公开中

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