4EM1
 
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2ZEV
 | | S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with Magnesium, IPP and BPH-715 | | Descriptor: | 3-(DECYLOXY)-1-(2,2-DIPHOSPHONOETHYL)PYRIDINIUM, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase, ... | | Authors: | Guo, R.T, Chen, C.K.-M, Cao, R, Oldfield, E, Wang, A.H.-J. | | Deposit date: | 2007-12-17 | | Release date: | 2008-12-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation
J.Am.Chem.Soc., 131, 2009
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2ZU5
 | | complex structure of SARS-CoV 3CL protease with TG-0205486 | | Descriptor: | 3C-like proteinase, N-[(benzyloxy)carbonyl]-O-tert-butyl-L-threonyl-N-[(1R)-4-cyclopropyl-4-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}butyl]-L-leucinamide | | Authors: | Hsu, M.F, Lee, C.C, Wang, A.H.-J. | | Deposit date: | 2008-10-12 | | Release date: | 2009-01-13 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
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2ZU1
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2ZYD
 | | Dimeric 6-phosphogluconate dehydrogenase complexed with glucose | | Descriptor: | 6-phosphogluconate dehydrogenase, decarboxylating, D-glucose | | Authors: | Chen, Y.-Y, Ko, T.-P, Lo, L.-P, Lin, C.-H, Wang, A.H.-J. | | Deposit date: | 2009-01-19 | | Release date: | 2009-09-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism
J.Struct.Biol., 169, 2010
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2ZU3
 | | Complex structure of CVB3 3C protease with TG-0204998 | | Descriptor: | 3C proteinase, N-[(benzyloxy)carbonyl]-3-[(2,2-dimethylpropanoyl)amino]-L-alanyl-N-[(1R)-4-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}pentyl]-L-leucinamide | | Authors: | Lee, C.C, Tsui, Y.C, Wang, A.H.-J. | | Deposit date: | 2008-10-12 | | Release date: | 2009-01-13 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
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2ZYA
 | | Dimeric 6-phosphogluconate dehydrogenase complexed with 6-phosphogluconate | | Descriptor: | 6-PHOSPHOGLUCONIC ACID, 6-phosphogluconate dehydrogenase, decarboxylating | | Authors: | Chen, Y.-Y, Ko, T.-P, Lo, L.-P, Lin, C.-H, Wang, A.H.-J. | | Deposit date: | 2009-01-19 | | Release date: | 2009-09-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism
J.Struct.Biol., 169, 2010
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3A30
 | | E. coli Gsp amidase C59 acetate modification | | Descriptor: | ACETATE ION, Bifunctional glutathionylspermidine synthetase/amidase | | Authors: | Pai, C.-H, Ko, T.-P, Chiang, B.-Y, Lin, C.-H, Wang, A.H.-J. | | Deposit date: | 2009-06-05 | | Release date: | 2010-05-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Protein S-thiolation by Glutathionylspermidine (Gsp): the role of Escherichia coli Gsp synthetASE/amidase in redox regulation
J.Biol.Chem., 285, 2010
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3OAC
 | | Mint deletion mutant of heterotetrameric geranyl pyrophosphate synthase in complex with ligands | | Descriptor: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, DIMETHYLALLYL S-THIOLODIPHOSPHATE, Geranyl diphosphate synthase large subunit, ... | | Authors: | Hsieh, F.-L, Chang, T.-H, Ko, T.-P, Wang, A.H.-J. | | Deposit date: | 2010-08-05 | | Release date: | 2010-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Enhanced specificity of mint geranyl pyrophosphate synthase by modifying the R-loop interactions
J.Mol.Biol., 404, 2010
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3KRF
 | | Mint heterotetrameric geranyl pyrophosphate synthase in complex with magnesium, IPP, and DMASPP (I) | | Descriptor: | 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, DIMETHYLALLYL S-THIOLODIPHOSPHATE, ... | | Authors: | Chang, T.-H, Hsieh, F.-L, Ko, T.-P, Wang, A.H.-J. | | Deposit date: | 2009-11-18 | | Release date: | 2010-02-23 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Plant Cell, 22, 2010
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3KRC
 | | Mint heterotetrameric geranyl pyrophosphate synthase in complex with IPP | | Descriptor: | 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Geranyl diphosphate synthase large subunit, ... | | Authors: | Chang, T.-H, Hsieh, F.-L, Ko, T.-P, Wang, A.H.-J. | | Deposit date: | 2009-11-18 | | Release date: | 2010-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Plant Cell, 22, 2010
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3KRP
 | | Mint heterotetrameric geranyl pyrophosphate synthase in complex with magnesium and GPP | | Descriptor: | 1,2-ETHANEDIOL, GERANYL DIPHOSPHATE, Geranyl diphosphate synthase large subunit, ... | | Authors: | Chang, T.-H, Hsieh, F.-L, Ko, T.-P, Wang, A.H.-J. | | Deposit date: | 2009-11-19 | | Release date: | 2010-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Plant Cell, 22, 2010
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3LCF
 | | The D-sialic acid aldolase mutant V251I | | Descriptor: | N-acetylneuraminate lyase, SULFATE ION | | Authors: | Chou, C.-Y, Wang, A.H.-J, Ko, T.-P. | | Deposit date: | 2010-01-11 | | Release date: | 2011-01-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251
To be Published
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3LCX
 | | L-KDO aldolase | | Descriptor: | N-acetylneuraminate lyase, SULFATE ION | | Authors: | Chou, C.-Y, Huang, K.-F, Wang, A.H.-J, Ko, T.-P. | | Deposit date: | 2010-01-12 | | Release date: | 2011-01-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251
To be Published
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3LCG
 | | The D-sialic acid aldolase mutant V251L | | Descriptor: | N-acetylneuraminate lyase, SULFATE ION | | Authors: | Chou, C.-Y, Wang, A.H.-J, Ko, T.-P. | | Deposit date: | 2010-01-11 | | Release date: | 2011-01-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251
To be Published
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3LBM
 | | D-sialic acid aldolase | | Descriptor: | N-acetylneuraminate lyase, SULFATE ION | | Authors: | Ko, T.-P, Chou, C.-Y, Wang, A.H.-J. | | Deposit date: | 2010-01-08 | | Release date: | 2011-01-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251
To be Published
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3LCL
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3LCI
 | | The D-sialic acid aldolase mutant V251W | | Descriptor: | N-acetylneuraminate lyase, SULFATE ION | | Authors: | Chou, C.-Y, Wang, A.H.-J, Ko, T.-P. | | Deposit date: | 2010-01-11 | | Release date: | 2011-01-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251
To be Published
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3LCH
 | | The D-sialic acid aldolase mutant V251R | | Descriptor: | N-acetylneuraminate lyase, SULFATE ION | | Authors: | Chou, C.-Y, Wang, A.H.-J, Ko, T.-P. | | Deposit date: | 2010-01-11 | | Release date: | 2011-01-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251
To be Published
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3LBC
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3LCW
 | | L-KDO aldolase complexed with hydroxypyruvate | | Descriptor: | 3-HYDROXYPYRUVIC ACID, N-acetylneuraminate lyase, SULFATE ION | | Authors: | Chou, C.-Y, Wang, A.H.-J, Ko, T.-P. | | Deposit date: | 2010-01-12 | | Release date: | 2011-01-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251
To be Published
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3Q6M
 | | Crystal Structure of Human MC-HSP90 in C2221 Space Group | | Descriptor: | Heat shock protein HSP 90-alpha, SULFATE ION | | Authors: | Lee, C.C, Lin, T.W, Ko, T.P, Wang, A.H.-J. | | Deposit date: | 2011-01-03 | | Release date: | 2011-06-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The hexameric structures of human heat shock protein 90
Plos One, 6, 2011
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3MHX
 | | Crystal Structure of Stenotrophomonas maltophilia FeoA complexed with Zinc: A Unique Procaryotic SH3 Domain Protein Possibly Acting as a Bacterial Ferrous Iron Transport Activating Factor | | Descriptor: | ACETATE ION, CHLORIDE ION, Putative ferrous iron transport protein A, ... | | Authors: | Chou, S.-H, Su, Y.-C, Chin, K.-H, Hung, H.-C, Shen, G.-H, Wang, A.H.-J. | | Deposit date: | 2010-04-09 | | Release date: | 2010-06-23 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of Stenotrophomonas maltophilia FeoA complexed with zinc: a unique prokaryotic SH3-domain protein that possibly acts as a bacterial ferrous iron-transport activating factor
Acta Crystallogr.,Sect.F, 66, 2010
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3Q6N
 | | Crystal Structure of Human MC-HSP90 in P21 space group | | Descriptor: | Heat shock protein HSP 90-alpha, SULFATE ION | | Authors: | Lee, C.C, Lin, T.W, Ko, T.P, Wang, A.H.-J. | | Deposit date: | 2011-01-03 | | Release date: | 2011-06-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | The hexameric structures of human heat shock protein 90
Plos One, 6, 2011
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3KRA
 | | Mint heterotetrameric geranyl pyrophosphate synthase in complex with magnesium | | Descriptor: | 1,2-ETHANEDIOL, Geranyl diphosphate synthase large subunit, Geranyl diphosphate synthase small subunit, ... | | Authors: | Chang, T.-H, Ko, T.-P, Hsieh, F.-L, Wang, A.H.-J. | | Deposit date: | 2009-11-18 | | Release date: | 2010-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Plant Cell, 22, 2010
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