4XT9
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![BU of 4xt9 by Molmil](/molmil-images/mine/4xt9) | RORgamma (263-509) complexed with GSK2435341A and SRC2 | Descriptor: | LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN, N-[4-(2,5-dichlorophenyl)-5-phenyl-1,3-thiazol-2-yl]-2-[4-(ethylsulfonyl)phenyl]acetamide, Nuclear receptor ROR-gamma, ... | Authors: | Wang, Y, Ma, Y. | Deposit date: | 2015-01-23 | Release date: | 2015-08-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Discovery of N-(4-aryl-5-aryloxy-thiazol-2-yl)-amides as potent ROR gamma t inverse agonists Bioorg.Med.Chem., 23, 2015
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6BFC
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![BU of 6bfc by Molmil](/molmil-images/mine/6bfc) | Cryo-EM structure of human insulin degrading enzyme in complex with insulin | Descriptor: | Insulin, Insulin-degrading enzyme | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | Deposit date: | 2017-10-26 | Release date: | 2017-12-27 | Last modified: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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6B3Q
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![BU of 6b3q by Molmil](/molmil-images/mine/6b3q) | Cryo-EM structure of human insulin degrading enzyme in complex with insulin | Descriptor: | Insulin, Insulin-degrading enzyme | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | Deposit date: | 2017-09-22 | Release date: | 2017-11-22 | Last modified: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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6B7Y
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![BU of 6b7y by Molmil](/molmil-images/mine/6b7y) | Cryo-EM structure of human insulin degrading enzyme | Descriptor: | Insulin-degrading enzyme | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | Deposit date: | 2017-10-05 | Release date: | 2017-11-08 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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6BF6
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![BU of 6bf6 by Molmil](/molmil-images/mine/6bf6) | Cryo-EM structure of human insulin degrading enzyme | Descriptor: | Insulin-degrading enzyme | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | Deposit date: | 2017-10-26 | Release date: | 2018-02-07 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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6B7Z
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![BU of 6b7z by Molmil](/molmil-images/mine/6b7z) | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11 heavy chain and FAB H11 light chain | Descriptor: | FAB H11 heavy chain, FAB H11 light chain, Insulin-degrading enzyme | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | Deposit date: | 2017-10-05 | Release date: | 2018-01-10 | Last modified: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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6BF9
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![BU of 6bf9 by Molmil](/molmil-images/mine/6bf9) | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain | Descriptor: | Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | Deposit date: | 2017-10-26 | Release date: | 2018-02-07 | Last modified: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (7.2 Å) | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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6BF7
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![BU of 6bf7 by Molmil](/molmil-images/mine/6bf7) | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain | Descriptor: | Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | Deposit date: | 2017-10-26 | Release date: | 2018-02-07 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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7BPU
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![BU of 7bpu by Molmil](/molmil-images/mine/7bpu) | |
5N6O
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![BU of 5n6o by Molmil](/molmil-images/mine/5n6o) | Wild type human Rac1-GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1 | Authors: | Cherfils, J, Ferrandez, Y. | Deposit date: | 2017-02-15 | Release date: | 2017-12-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Allosteric inhibition of the guanine nucleotide exchange factor DOCK5 by a small molecule. Sci Rep, 7, 2017
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4X3O
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![BU of 4x3o by Molmil](/molmil-images/mine/4x3o) | Sirt2 in complex with a myristoyl peptide | Descriptor: | 1,2-ETHANEDIOL, NAD-dependent protein deacetylase sirtuin-2, ZINC ION, ... | Authors: | Wang, Y, Zhang, W.Z, Hao, Q. | Deposit date: | 2014-12-01 | Release date: | 2016-01-13 | Last modified: | 2022-04-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Deacylation Mechanism by SIRT2 Revealed in the 1'-SH-2'-O-Myristoyl Intermediate Structure. Cell Chem Biol, 24, 2017
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4ZHU
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![BU of 4zhu by Molmil](/molmil-images/mine/4zhu) | Crystal structure of a bacterial repressor protein | Descriptor: | SULFATE ION, YfiR | Authors: | Li, S, Li, T, Wang, Y, Bartlam, M. | Deposit date: | 2015-04-27 | Release date: | 2016-04-27 | Method: | X-RAY DIFFRACTION (2.3968 Å) | Cite: | Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1 Sci Rep, 5, 2015
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4ZHW
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![BU of 4zhw by Molmil](/molmil-images/mine/4zhw) | |
2RDO
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![BU of 2rdo by Molmil](/molmil-images/mine/2rdo) | 50S subunit with EF-G(GDPNP) and RRF bound | Descriptor: | 23S RIBOSOMAL RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ... | Authors: | Gao, N, Zavialov, A.V, Ehrenberg, M, Frank, J. | Deposit date: | 2007-09-24 | Release date: | 2008-03-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9.1 Å) | Cite: | Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits. J.Mol.Biol., 374, 2007
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7WOS
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![BU of 7wos by Molmil](/molmil-images/mine/7wos) | The state 3 of Omicron Spike with bispecific antibody FD01 | Descriptor: | 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ... | Authors: | Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. | Deposit date: | 2022-01-22 | Release date: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies Cell Discov, 8, 2022
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7WOQ
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![BU of 7woq by Molmil](/molmil-images/mine/7woq) | The state 1 of Omicron Spike with bispecific antibody FD01 | Descriptor: | 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. | Deposit date: | 2022-01-22 | Release date: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies Cell Discov, 8, 2022
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7WOU
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![BU of 7wou by Molmil](/molmil-images/mine/7wou) | The state 4 of Omicron Spike with bispecific antibody FD01 | Descriptor: | 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ... | Authors: | Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. | Deposit date: | 2022-01-22 | Release date: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies Cell Discov, 8, 2022
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7WOP
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![BU of 7wop by Molmil](/molmil-images/mine/7wop) | The local refined map of Omicron spike with bispecific antibody FD01 | Descriptor: | 16L9, GW01, Spike protein S1 | Authors: | Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. | Deposit date: | 2022-01-22 | Release date: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies Cell Discov, 8, 2022
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7WOR
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![BU of 7wor by Molmil](/molmil-images/mine/7wor) | The state 2 of Omicron Spike with bispecific antibody FD01 | Descriptor: | 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ... | Authors: | Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. | Deposit date: | 2022-01-22 | Release date: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies Cell Discov, 8, 2022
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7WOV
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![BU of 7wov by Molmil](/molmil-images/mine/7wov) | The state 5 of Omicron Spike with bispecific antibody FD01 | Descriptor: | 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ... | Authors: | Zhang, X, Zhan, W.Q, Sun, L, Chen, Z.G. | Deposit date: | 2022-01-22 | Release date: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.87 Å) | Cite: | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies Cell Discov, 8, 2022
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7WOW
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![BU of 7wow by Molmil](/molmil-images/mine/7wow) | The state 6 of Omicron Spike with bispecific antibody FD01 | Descriptor: | 16L9 Fv, GW01 Fv, Spike glycoprotein | Authors: | Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. | Deposit date: | 2022-01-22 | Release date: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (6.11 Å) | Cite: | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies Cell Discov, 8, 2022
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6B82
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![BU of 6b82 by Molmil](/molmil-images/mine/6b82) | Zebra Fish CYP-450 17A1 Mutant Abiraterone Complex | Descriptor: | ACETATE ION, Abiraterone, CHLORIDE ION, ... | Authors: | Pallan, P.S, Egli, M. | Deposit date: | 2017-10-05 | Release date: | 2017-12-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.03 Å) | Cite: | Inherent steroid 17 alpha ,20-lyase activity in defunct cytochrome P450 17A enzymes. J. Biol. Chem., 293, 2018
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5B76
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![BU of 5b76 by Molmil](/molmil-images/mine/5b76) | |
1XPC
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![BU of 1xpc by Molmil](/molmil-images/mine/1xpc) | |
1XP1
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![BU of 1xp1 by Molmil](/molmil-images/mine/1xp1) | HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 15 | Descriptor: | (2S,3R)-2-(4-{2-[(3R,4R)-3,4-DIMETHYLPYRROLIDIN-1-YL]ETHOXY}PHENYL)-3-(4-HYDROXYPHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6- OL, Estrogen receptor | Authors: | Fitzgerald, P.M.D, Sharma, N. | Deposit date: | 2004-10-07 | Release date: | 2004-12-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers. Bioorg.Med.Chem.Lett., 15, 2005
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