4DKO
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![BU of 4dko by Molmil](/molmil-images/mine/4dko) | Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with TS-II-224 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 gp120 core, ... | Authors: | Kwon, Y.D, LaLonde, J.M, Jones, D.M, Sun, A.W, Courter, J.R, Soeta, T, Kobayashi, T, Princiotto, A.M, Wu, X, Mascola, J, Schon, A, Freire, E, Sodroski, J, Madani, N, Smith III, A.B, Kwong, P.D. | Deposit date: | 2012-02-03 | Release date: | 2012-05-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.981 Å) | Cite: | Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors. J.Med.Chem., 55, 2012
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4DKR
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![BU of 4dkr by Molmil](/molmil-images/mine/4dkr) | Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with AWS-I-169 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 gp120 core, ... | Authors: | Kwon, Y.D, LaLonde, J.M, Jones, D.M, Sun, A.W, Courter, J.R, Soeta, T, Kobayashi, T, Princiotto, A.M, Wu, X, Mascola, J, Schon, A, Freire, E, Sodroski, J, Madani, N, Smith III, A.B, Kwong, P.D. | Deposit date: | 2012-02-03 | Release date: | 2012-05-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors. J.Med.Chem., 55, 2012
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4DKQ
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![BU of 4dkq by Molmil](/molmil-images/mine/4dkq) | Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with DMJ-I-228 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N-[(1S,2S)-2-carbamimidamido-2,3-dihydro-1H-inden-1-yl]-N'-(4-chloro-3-fluorophenyl)ethanediamide, ... | Authors: | Kwon, Y.D, LaLonde, J.M, Jones, D.M, Sun, A.W, Courter, J.R, Soeta, T, Kobayashi, T, Princiotto, A.M, Wu, X, Mascola, J, Schon, A, Freire, E, Sodroski, J, Madani, N, Smith III, A.B, Kwong, P.D. | Deposit date: | 2012-02-03 | Release date: | 2012-05-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.888 Å) | Cite: | Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors. J.Med.Chem., 55, 2012
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4FAB
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![BU of 4fab by Molmil](/molmil-images/mine/4fab) | THREE-DIMENSIONAL STRUCTURE OF A FLUORESCEIN-FAB COMPLEX CRYSTALLIZED IN 2-METHYL-2,4-PENTANEDIOL | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, IGG2A-KAPPA 4-4-20 FAB (HEAVY CHAIN), ... | Authors: | Herron, J.N, He, X, Mason, M.L, Vossjunior, E.W, Edmundson, A.B. | Deposit date: | 1989-04-10 | Release date: | 1990-07-15 | Last modified: | 2017-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Three-dimensional structure of a fluorescein-Fab complex crystallized in 2-methyl-2,4-pentanediol. Proteins, 5, 1989
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1HZS
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![BU of 1hzs by Molmil](/molmil-images/mine/1hzs) | Crystal structure of a peptide nucleic acid duplex (BT-PNA) containing a bicyclic analogue of thymine | Descriptor: | PEPTIDE NUCLEIC ACID | Authors: | Eldrup, A.B, Nielsen, B.B, Haaima, G, Rasmussen, H, Kastrup, J.S, Christensen, C, Nielsen, P.E. | Deposit date: | 2001-01-26 | Release date: | 2001-07-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | 1,8-Naphthyridin-2(1H)-ones. Novel Bicyclic and Tricyclic Analogues of Thymine in Peptide Nucleic Acids (PNAs) Eur.J.Org.Chem., 9, 2001
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1I1G
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![BU of 1i1g by Molmil](/molmil-images/mine/1i1g) | CRYSTAL STRUCTURE OF THE LRP-LIKE TRANSCRIPTIONAL REGULATOR FROM THE ARCHAEON PYROCOCCUS FURIOSUS | Descriptor: | TRANSCRIPTIONAL REGULATOR LRPA | Authors: | Leonard, P.M, Smits, S.H.J, Sedelnikova, S.E, Brinkman, A.B, de Vos, W.M, van der Oost, J, Rice, D.W, Rafferty, J.B. | Deposit date: | 2001-02-01 | Release date: | 2002-02-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the Lrp-like transcriptional regulator from the archaeon Pyrococcus furiosus. EMBO J., 20, 2001
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1IRQ
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![BU of 1irq by Molmil](/molmil-images/mine/1irq) | Crystal structure of omega transcriptional repressor at 1.5A resolution | Descriptor: | omega transcriptional repressor | Authors: | Murayama, K, Orth, P, De La Hoz, A.B, Alonso, J.C, Saenger, W. | Deposit date: | 2001-10-11 | Release date: | 2001-12-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of omega transcriptional repressor encoded by Streptococcus pyogenes plasmid pSM19035 at 1.5 A resolution. J.Mol.Biol., 314, 2001
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1IGM
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![BU of 1igm by Molmil](/molmil-images/mine/1igm) | |
1ITG
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![BU of 1itg by Molmil](/molmil-images/mine/1itg) | CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HIV-1 INTEGRASE: SIMILARITY TO OTHER POLYNUCLEOTIDYL TRANSFERASES | Descriptor: | CACODYLATE ION, HIV-1 INTEGRASE | Authors: | Dyda, F, Hickman, A.B, Jenkins, T.M, Engelman, A, Craigie, R, Davies, D.R. | Deposit date: | 1994-11-21 | Release date: | 1995-05-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases. Science, 266, 1994
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1JQF
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![BU of 1jqf by Molmil](/molmil-images/mine/1jqf) | Human Transferrin N-Lobe Mutant H249Q | Descriptor: | CARBONATE ION, FE (III) ION, POTASSIUM ION, ... | Authors: | Baker, H.M, Mason, A.B, He, Q.-Y, MacGillivray, R.T.A, Baker, E.N. | Deposit date: | 2001-08-06 | Release date: | 2001-10-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Ligand variation in the transferrin family: the crystal structure of the H249Q mutant of the human transferrin N-lobe as a model for iron binding in insect transferrins. Biochemistry, 40, 2001
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1IC0
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![BU of 1ic0 by Molmil](/molmil-images/mine/1ic0) | RED COPPER PROTEIN NITROSOCYANIN FROM NITROSOMONAS EUROPAEA | Descriptor: | COPPER (II) ION, Nitrosocyanin | Authors: | Lieberman, R.L, Arciero, D.M, Hooper, A.B, Rosenzweig, A.C. | Deposit date: | 2001-03-29 | Release date: | 2001-06-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of a novel red copper protein from Nitrosomonas europaea. Biochemistry, 40, 2001
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1IBY
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![BU of 1iby by Molmil](/molmil-images/mine/1iby) | RED COPPER PROTEIN NITROSOCYANIN FROM NITROSOMONAS EUROPAEA | Descriptor: | COPPER (II) ION, HEXANE-1,6-DIOL, NITROSOCYANIN | Authors: | Lieberman, R.L, Arciero, D.M, Hooper, A.B, Rosenzweig, A.C. | Deposit date: | 2001-03-29 | Release date: | 2001-06-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of a novel red copper protein from Nitrosomonas europaea. Biochemistry, 40, 2001
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1I82
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![BU of 1i82 by Molmil](/molmil-images/mine/1i82) | FAMILY 9 CARBOHYDRATE-BINDING MODULE FROM THERMOTOGA MARITIMA XYLANASE 10A WITH CELLOBIOSE | Descriptor: | CALCIUM ION, ENDO-1,4-BETA-XYLANASE A, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | Notenboom, V, Boraston, A.B, Warren, R.A.J, Kilburn, D.G, Rose, D.R. | Deposit date: | 2001-03-12 | Release date: | 2001-06-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of the family 9 carbohydrate-binding module from Thermotoga maritima xylanase 10A in native and ligand-bound forms. Biochemistry, 40, 2001
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1I8U
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![BU of 1i8u by Molmil](/molmil-images/mine/1i8u) | FAMILY 9 CARBOHYDRATE-BINDING MODULE FROM THERMOTOGA MARITIMA XYLANASE 10A | Descriptor: | CALCIUM ION, ENDO-1,4-BETA-XYLANASE A | Authors: | Notenboom, V, Boraston, A.B, Warren, R.A.J, Kilburn, D.G, Rose, D.R. | Deposit date: | 2001-03-16 | Release date: | 2001-06-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of the family 9 carbohydrate-binding module from Thermotoga maritima xylanase 10A in native and ligand-bound forms. Biochemistry, 40, 2001
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1IBZ
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![BU of 1ibz by Molmil](/molmil-images/mine/1ibz) | RED COPPER PROTEIN NITROSOCYANIN FROM NITROSOMONAS EUROPAEA | Descriptor: | COPPER (II) ION, NITROSOCYANIN | Authors: | Lieberman, R.L, Arciero, D.M, Hooper, A.B, Rosenzweig, A.C. | Deposit date: | 2001-03-29 | Release date: | 2001-06-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of a novel red copper protein from Nitrosomonas europaea. Biochemistry, 40, 2001
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1KLD
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![BU of 1kld by Molmil](/molmil-images/mine/1kld) | SOLUTION STRUCTURE OF TGF-B1, NMR, MODELS 18-33 OF 33 STRUCTURES | Descriptor: | TRANSFORMING GROWTH FACTOR-BETA 1 | Authors: | Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A. | Deposit date: | 1996-01-16 | Release date: | 1996-08-17 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2. Biochemistry, 35, 1996
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1KTZ
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![BU of 1ktz by Molmil](/molmil-images/mine/1ktz) | Crystal Structure of the Human TGF-beta Type II Receptor Extracellular Domain in Complex with TGF-beta3 | Descriptor: | TGF-beta Type II Receptor, TRANSFORMING GROWTH FACTOR BETA 3 | Authors: | Hart, P.J, Deep, S, Taylor, A.B, Shu, Z, Hinck, C.S, Hinck, A.P. | Deposit date: | 2002-01-18 | Release date: | 2002-02-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex. Nat.Struct.Biol., 9, 2002
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1KNL
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![BU of 1knl by Molmil](/molmil-images/mine/1knl) | Streptomyces lividans Xylan Binding Domain cbm13 | Descriptor: | ENDO-1,4-BETA-XYLANASE A, GLYCEROL | Authors: | Notenboom, V, Boraston, A.B, Williams, S.J, Kilburn, D.G, Rose, D.R. | Deposit date: | 2001-12-19 | Release date: | 2002-06-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | High-resolution crystal structures of the lectin-like xylan binding domain from Streptomyces lividans xylanase 10A with bound substrates reveal a novel mode of xylan binding. Biochemistry, 41, 2002
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1KLA
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![BU of 1kla by Molmil](/molmil-images/mine/1kla) | SOLUTION STRUCTURE OF TGF-B1, NMR, MODELS 1-17 OF 33 STRUCTURES | Descriptor: | TRANSFORMING GROWTH FACTOR-BETA 1 | Authors: | Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A. | Deposit date: | 1996-01-16 | Release date: | 1996-08-17 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2. Biochemistry, 35, 1996
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1I8A
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![BU of 1i8a by Molmil](/molmil-images/mine/1i8a) | FAMILY 9 CARBOHYDRATE-BINDING MODULE FROM THERMOTOGA MARITIMA XYLANASE 10A WITH GLUCOSE | Descriptor: | CALCIUM ION, ENDO-1,4-BETA-XYLANASE A, beta-D-glucopyranose | Authors: | Notenboom, V, Boraston, A.B, Warren, R.A.J, Kilburn, D.G, Rose, D.R. | Deposit date: | 2001-03-12 | Release date: | 2001-06-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of the family 9 carbohydrate-binding module from Thermotoga maritima xylanase 10A in native and ligand-bound forms. Biochemistry, 40, 2001
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1K4T
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![BU of 1k4t by Molmil](/molmil-images/mine/1k4t) | HUMAN DNA TOPOISOMERASE I (70 KDA) IN COMPLEX WITH THE POISON TOPOTECAN AND COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX | Descriptor: | (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, 2-(1-DIMETHYLAMINOMETHYL-2-HYDROXY-8-HYDROXYMETHYL-9-OXO-9,11-DIHYDRO-INDOLIZINO[1,2-B]QUINOLIN-7-YL)-2-HYDROXY-BUTYRIC ACID, 5'-D(*(TGP)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', ... | Authors: | Staker, B.L, Hjerrild, K, Feese, M.D, Behnke, C.A, Burgin Jr, A.B, Stewart, L.J. | Deposit date: | 2001-10-08 | Release date: | 2002-12-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The mechanism of topoisomerase I poisoning by a camptothecin analog Proc.Natl.Acad.Sci.USA, 99, 2002
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1K4S
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![BU of 1k4s by Molmil](/molmil-images/mine/1k4s) | HUMAN DNA TOPOISOMERASE I IN COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX | Descriptor: | 5'-D(*(SPT)P*GP*AP*AP*AP*AP*AP*(5IU)P*(5IU)P*(5IU)P*(5IU)P*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*(5IU)P*(5IU))-3', 5'-D(*AP*AP*AP*AP*AP*TP*(IDO)UP*(IDO)UP*(IDO)UP*(IDO)UP*CP*AP*AP*AP*GP*(IDO)UP*CP*(IDO)UP*(IDO)UP*(IDO)UP*(IDO)UP*T)-3', ... | Authors: | Staker, B.L, Hjerrild, K, Feese, M.D, Behnke, C.A, Burgin Jr, A.B, Stewart, L.J. | Deposit date: | 2001-10-08 | Release date: | 2002-12-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The mechanism of topoisomerase I poisoning by a camptothecin analog Proc.Natl.Acad.Sci.USA, 99, 2002
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1K8S
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![BU of 1k8s by Molmil](/molmil-images/mine/1k8s) | BULGED ADENOSINE IN AN RNA DUPLEX | Descriptor: | 5'-R(*GP*CP*GP*GP*CP*AP*CP*CP*UP*GP*CP*C)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*UP*GP*CP*CP*GP*C)-3' | Authors: | Thiviyanathan, V, Guliaev, A.B, Leontis, N.B, Gorenstein, D.G. | Deposit date: | 2001-10-25 | Release date: | 2001-11-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution conformation of a bulged adenosine base in an RNA duplex by relaxation matrix refinement. J.Mol.Biol., 300, 2000
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1KNM
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![BU of 1knm by Molmil](/molmil-images/mine/1knm) | Streptomyces lividans Xylan Binding Domain cbm13 in Complex with Lactose | Descriptor: | ENDO-1,4-BETA-XYLANASE A, GLYCEROL, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Notenboom, V, Boraston, A.B, Williams, S.J, Kilburn, D.G, Rose, D.R. | Deposit date: | 2001-12-19 | Release date: | 2002-06-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | High-resolution crystal structures of the lectin-like xylan binding domain from Streptomyces lividans xylanase 10A with bound substrates reveal a novel mode of xylan binding. Biochemistry, 41, 2002
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1KLC
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![BU of 1klc by Molmil](/molmil-images/mine/1klc) | SOLUTION STRUCTURE OF TGF-B1, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | TRANSFORMING GROWTH FACTOR-BETA 1 | Authors: | Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A. | Deposit date: | 1996-01-16 | Release date: | 1996-08-17 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2. Biochemistry, 35, 1996
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