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3EO3
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BU of 3eo3 by Molmil
Crystal structure of the N-acetylmannosamine kinase domain of human GNE protein
Descriptor: Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, UNKNOWN ATOM OR ION, ZINC ION
Authors:Nedyalkova, L, Tong, Y, Rabeh, W.M, Hong, B, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2008-09-26
Release date:2008-10-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Crystal structure of the N-acetylmannosamine kinase domain of GNE.
Plos One, 4, 2009
3FEG
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BU of 3feg by Molmil
Crystal structure of human choline kinase beta in complex with phosphorylated hemicholinium-3 and adenosine nucleotide
Descriptor: (2S)-2-[4'-({dimethyl[2-(phosphonooxy)ethyl]ammonio}acetyl)biphenyl-4-yl]-2-hydroxy-4,4-dimethylmorpholin-4-ium, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Hong, B.S, Tempel, W, Rabeh, W.M, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H.W, Structural Genomics Consortium (SGC)
Deposit date:2008-11-29
Release date:2008-12-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.302 Å)
Cite:Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity.
J.Biol.Chem., 285, 2010
6KE4
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BU of 6ke4 by Molmil
ABloop reengineered Ferritin Nanocage
Descriptor: CALCIUM ION, CHLORIDE ION, FE (III) ION, ...
Authors:Wang, W.M, Wang, H.F.
Deposit date:2019-07-03
Release date:2019-10-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:AB loop engineered ferritin nanocages for drug loading under benign experimental conditions.
Chem.Commun.(Camb.), 55, 2019
6KE2
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BU of 6ke2 by Molmil
ABloop reengineered Ferritin Nanocage
Descriptor: CALCIUM ION, CHLORIDE ION, FE (III) ION, ...
Authors:Wang, W.M, Wang, H.F.
Deposit date:2019-07-03
Release date:2019-10-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:AB loop engineered ferritin nanocages for drug loading under benign experimental conditions.
Chem.Commun.(Camb.), 55, 2019
6IVE
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BU of 6ive by Molmil
Molecular structure of a thermostable and a Zinc ion binding gamma-class carbonic anhydrase
Descriptor: Ferripyochelin-binding protein, PHOSPHATE ION, ZINC ION
Authors:Wang, W.M, Wang, H.F.
Deposit date:2018-12-03
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular structure of thermostable and zinc-ion-binding gamma-class carbonic anhydrases.
Biometals, 32, 2019
2GVF
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BU of 2gvf by Molmil
HCV NS3-4A protease domain complexed with a macrocyclic ketoamide inhibitor, SCH419021
Descriptor: (6R,8S,11S)-11-CYCLOHEXYL-N-(1-{[(2-{[(1S)-2-(DIMETHYLAMINO)-2-OXO-1-PHENYLETHYL]AMINO}-2-OXOETHYL)AMINO](OXO)ACETYL}BUTYL)-10,13-DIOXO-2,5-DIOXA-9,12-DIAZATRICYCLO[14.3.1.1~6,9~]HENICOSA-1(20),16,18-TRIENE-8-CARBOXAMIDE, Polyprotein, ZINC ION, ...
Authors:Arasappan, A, Njoroge, F.G, Chen, K.X, Venkatraman, S, Parekh, T.N, Gu, H, Pichardo, J, Butkiewicz, N, Prongay, A, Madison, V, Girijavallabhan, V.
Deposit date:2006-05-02
Release date:2007-01-23
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:P2-P4 macrocyclic inhibitors of hepatitis C virus NS3-4A serine protease.
Bioorg.Med.Chem.Lett., 16, 2006
2H6E
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BU of 2h6e by Molmil
Crystal structure of the D-arabinose dehydrogenase from Sulfolobus solfataricus
Descriptor: D-arabinose 1-dehydrogenase, ZINC ION
Authors:Brouns, S.J.J, Turnbull, A.P, Akerboom, J, Willemen, H.L.D.M, De Vos, W.M, Van der Oost, J.
Deposit date:2006-05-31
Release date:2007-06-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure and Biochemical Properties of the d-Arabinose Dehydrogenase from Sulfolobus solfataricus
J.Mol.Biol., 371, 2007
2HBS
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BU of 2hbs by Molmil
THE HIGH RESOLUTION CRYSTAL STRUCTURE OF DEOXYHEMOGLOBIN S
Descriptor: HEMOGLOBIN S (DEOXY), ALPHA CHAIN, BETA CHAIN, ...
Authors:Harrington, D.J, Adachi, K, Royer Junior, W.E.
Deposit date:1997-05-06
Release date:1997-07-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The high resolution crystal structure of deoxyhemoglobin S.
J.Mol.Biol., 272, 1997
2K8C
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BU of 2k8c by Molmil
Solution structure of PLAA family ubiquitin binding domain (PFUC) trans isomer in complex with ubiquitin
Descriptor: Phospholipase A-2-activating protein, Ubiquitin
Authors:Fu, Q.S, Zhou, C.J, Gao, H.C, Lin, D.H, Hu, H.Y.
Deposit date:2008-09-04
Release date:2009-05-05
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural Basis for Ubiquitin Recognition by a Novel Domain from Human Phospholipase A2-activating Protein.
J.Biol.Chem., 284, 2009
2KOJ
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BU of 2koj by Molmil
Solution structure of mouse Par-3 PDZ2 (residues 450-558)
Descriptor: Partitioning defective 3 homolog
Authors:Volkman, B.F, Tyler, R.C, Peterson, F.C, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2009-09-23
Release date:2009-11-10
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Macromolecular Structure Determination by NMR Sepectroscopy
Structural Bioinformatics, 2nd edition, 2009
7XV4
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BU of 7xv4 by Molmil
Crystal structure of RPA70N-ATRIP fusion
Descriptor: ATR-interacting protein, Replication protein A 70 kDa DNA-binding subunit
Authors:Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C.
Deposit date:2022-05-20
Release date:2023-06-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
7XV1
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BU of 7xv1 by Molmil
Crystal structure of RPA70N-HelB fusion
Descriptor: DNA helicase B, Replication protein A 70 kDa DNA-binding subunit
Authors:Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C.
Deposit date:2022-05-20
Release date:2023-06-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
7XUT
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BU of 7xut by Molmil
Crystal structure of RPA70N-WRN fusion
Descriptor: fusion protein of Replication protein A 70 kDa DNA-binding subunit and Werner syndrome ATP-dependent helicase
Authors:Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C.
Deposit date:2022-05-19
Release date:2023-06-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
2K89
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BU of 2k89 by Molmil
Solution structure of a novel Ubiquitin-binding domain from Human PLAA (PFUC, Gly76-Pro77 cis isomer)
Descriptor: Phospholipase A-2-activating protein
Authors:Fu, Q.S, Zhou, C.J, Gao, H.C, Lin, D.H, Hu, H.Y.
Deposit date:2008-09-04
Release date:2009-05-05
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural Basis for Ubiquitin Recognition by a Novel Domain from Human Phospholipase A2-activating Protein.
J.Biol.Chem., 284, 2009
7XV0
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BU of 7xv0 by Molmil
Crystal structure of RPA70N-BLMp1 fusion
Descriptor: Bloom syndrome protein, Replication protein A 70 kDa DNA-binding subunit
Authors:Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C.
Deposit date:2022-05-20
Release date:2023-06-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
2K8B
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BU of 2k8b by Molmil
Solution structure of PLAA family ubiquitin binding domain (PFUC) cis isomer in complex with ubiquitin
Descriptor: Phospholipase A-2-activating protein, Ubiquitin
Authors:Fu, Q.S, Zhou, C.J, Gao, H.C, Lin, D.H, Hu, H.Y.
Deposit date:2008-09-04
Release date:2009-05-05
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural Basis for Ubiquitin Recognition by a Novel Domain from Human Phospholipase A2-activating Protein.
J.Biol.Chem., 284, 2009
5DNK
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BU of 5dnk by Molmil
The structure of PKMT1 from Rickettsia prowazekii in complex with AdoHcy
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, protein lysine methyltransferase 1
Authors:Noinaj, N, Abeykoon, A, He, Y, Yang, D.C, Buchanan, S.K.
Deposit date:2015-09-10
Release date:2016-08-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights into Substrate Recognition and Catalysis in Outer Membrane Protein B (OmpB) by Protein-lysine Methyltransferases from Rickettsia.
J.Biol.Chem., 291, 2016
7XUW
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BU of 7xuw by Molmil
Crystal structure of RPA70N-BLMp2 fusion
Descriptor: fusion protein of Replication protein A 70 kDa DNA-binding subunit and Bloom syndrome protein
Authors:Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C.
Deposit date:2022-05-20
Release date:2023-06-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
7XUV
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BU of 7xuv by Molmil
Crystal structure of RPA70N-RMI1 fusion
Descriptor: RecQ-mediated genome instability protein 1, Replication protein A 70 kDa DNA-binding subunit
Authors:Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C.
Deposit date:2022-05-20
Release date:2023-06-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
2LNQ
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BU of 2lnq by Molmil
40-residue D23N beta amyloid fibril
Descriptor: P3(40)
Authors:Qiang, W, Yau, W, Luo, Y, Mattson, M.P, Tycko, R.
Deposit date:2012-01-03
Release date:2012-02-08
Last modified:2024-05-15
Method:SOLID-STATE NMR
Cite:Antiparallel beta-sheet architecture in Iowa-mutant beta-amyloid fibrils.
Proc.Natl.Acad.Sci.USA, 109, 2012
2LMQ
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BU of 2lmq by Molmil
Structural Model for a 40-residue Beta-Amyloid Fibril with Three-Fold Symmetry, Negative Stagger
Descriptor: Beta-amyloid protein 40
Authors:Tycko, R, Paravastu, A.
Deposit date:2011-12-09
Release date:2011-12-28
Last modified:2024-05-01
Method:SOLID-STATE NMR
Cite:Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils.
Proc. Natl. Acad. Sci. U.S.A., 105, 2008
2LJL
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BU of 2ljl by Molmil
NMR structure of Hsp12 in the presence of DPC
Descriptor: 12 kDa heat shock protein
Authors:Singarapu, K, Markley, J, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2011-09-20
Release date:2011-10-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural characterization of Hsp12, the heat shock protein from Saccharomyces cerevisiae, in aqueous solution where it is intrinsically disordered and in detergent micelles where it is locally alpha-helical.
J.Biol.Chem., 286, 2011
5EZ8
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BU of 5ez8 by Molmil
A de novo designed heptameric coiled coil CC-Hept-I-C-I
Descriptor: CC-Hept-I-C-I
Authors:Burton, A.J, Brady, R.L, Woolfson, D.N.
Deposit date:2015-11-26
Release date:2016-07-06
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Installing hydrolytic activity into a completely de novo protein framework.
Nat.Chem., 8, 2016
5EZA
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BU of 5eza by Molmil
A de novo designed heptameric coiled coil CC-Hept-I18C-L22H
Descriptor: CC-Hept-C-H-I, GLYCEROL
Authors:Burton, A.J, Brady, R.L, Woolfson, D.N.
Deposit date:2015-11-26
Release date:2016-07-06
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Installing hydrolytic activity into a completely de novo protein framework.
Nat.Chem., 8, 2016
5EZE
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BU of 5eze by Molmil
A de novo designed heptameric coiled coil CC-Hept-I18betaMeCys-L22H-I25E
Descriptor: CC-Hept-bMeCys-His-Glu, GLYCEROL
Authors:Burton, A.J, Brady, R.L, Woolfson, D.N.
Deposit date:2015-11-26
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Installing hydrolytic activity into a completely de novo protein framework.
Nat.Chem., 8, 2016

238582

数据于2025-07-09公开中

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