2K06
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2JX2
| Solution conformation of RNA-bound NELF-E RRM | Descriptor: | Negative elongation factor E | Authors: | Jampani, N, Schweimer, K, Wenzel, S, Woehrl, B.M, Roesch, P. | Deposit date: | 2007-11-02 | Release date: | 2008-04-08 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NELF-E RRM Undergoes Major Structural Changes in Flexible Protein Regions on Target RNA Binding Biochemistry, 47, 2008
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2LQ8
| Domain interaction in Thermotoga maritima NusG | Descriptor: | Transcription antitermination protein nusG | Authors: | Droegemueller, J, Stegmann, C, Burmann, B, Roesch, P, Wahl, M.C, Schweimer, K. | Deposit date: | 2012-02-27 | Release date: | 2013-01-23 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | An Autoinhibited State in the Structure of Thermotoga maritima NusG. Structure, 21, 2013
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2LPX
| Solution Structure of Strawberry Allergen Fra a 1e | Descriptor: | Major strawberry allergen Fra a 1-E | Authors: | Seutter von Loetzen, C, Hartl-Spiegelhauer, O, Schweimer, K, Schwab, W, Roesch, P. | Deposit date: | 2012-02-20 | Release date: | 2012-03-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of the strawberry allergen Fra a 1. Biosci.Rep., 32, 2012
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2JVV
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2JNZ
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2LCL
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2LSN
| Solution structure of PFV RNase H domain | Descriptor: | RNase H | Authors: | Leo, B, Schweimer, K, Woehrl, B. | Deposit date: | 2012-05-03 | Release date: | 2012-10-17 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The solution structure of the prototype foamy virus RNase H domain indicates an important role of the basic loop in substrate binding. Retrovirology, 9, 2012
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1O8R
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1TBC
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1TAC
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1PFD
| THE SOLUTION STRUCTURE OF HIGH PLANT PARSLEY [2FE-2S] FERREDOXIN, NMR, 18 STRUCTURES | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FERREDOXIN | Authors: | Im, S.-C, Liu, G, Luchinat, C, Sykes, A.G, Bertini, I. | Deposit date: | 1998-05-05 | Release date: | 1999-05-11 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The solution structure of parsley [2Fe-2S]ferredoxin. Eur.J.Biochem., 258, 1998
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4Q1N
| Structure-based design of 4-hydroxy-3,5-substituted piperidines as direct renin inhibitors | Descriptor: | (3S,4R,5R)-N-cyclopropyl-N'-[(2R)-1-ethoxy-4-methylpentan-2-yl]-4-hydroxy-N-[5-(propan-2-yl)pyridin-2-yl]piperidine-3,5-dicarboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | Authors: | Schiering, N, D'Arcy, A, Irie, O, Yokokawa, F. | Deposit date: | 2014-04-04 | Release date: | 2014-08-06 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structure-based design of substituted piperidines as a new class of highly efficacious oral direct Renin inhibitors. ACS Med Chem Lett, 5, 2014
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4PYV
| Crystal structure of renin in complex with compound4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, Renin, ... | Authors: | Ostermann, N, Zink, F. | Deposit date: | 2014-03-28 | Release date: | 2014-10-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structure-based design of substituted piperidines as a new class of highly efficacious oral direct Renin inhibitors. ACS Med Chem Lett, 5, 2014
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7KFA
| PCSK9 in complex with PCSK9i a 13mer cyclic peptide LDLR disruptor | Descriptor: | 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, CALCIUM ION, Proprotein convertase subtilisin/kexin type 9, ... | Authors: | Chopra, R, Xu, M, Spraggon, G. | Deposit date: | 2020-10-13 | Release date: | 2021-11-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Identification of a PCSK9-LDLR disruptor peptide with in vivo function. Cell Chem Biol, 29, 2022
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7KEV
| PCSK9 in complex with a cyclic peptide LDLR disruptor | Descriptor: | CALCIUM ION, Proprotein convertase subtilisin/kexin type 9, Proprotein convertase subtilisin/kexin type 9 Propeptide, ... | Authors: | Spraggon, G, Chopra, R. | Deposit date: | 2020-10-12 | Release date: | 2021-11-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Identification of a PCSK9-LDLR disruptor peptide with in vivo function. Cell Chem Biol, 29, 2022
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