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2OJ5
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BU of 2oj5 by Molmil
Crystal Structure of Reovirus T3D Attachment Protein Sigma1 head domain wild-type at 1.75 A resolution
Descriptor: GLYCEROL, MAGNESIUM ION, Viral attachment protein sigma 1
Authors:Stehle, T, Schelling, P, Kirchner, E, Dermody, T.S.
Deposit date:2007-01-12
Release date:2007-02-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The Reovirus Sigma1 Aspartic Acid Sandwich: A TRIMERIZATION MOTIF POISED FOR CONFORMATIONAL CHANGE.
J.Biol.Chem., 282, 2007
2OJ6
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BU of 2oj6 by Molmil
Crystal Structure of Reovirus T3D Attachment Protein Sigma1 head domain D345N mutant
Descriptor: MAGNESIUM ION, Viral attachment protein sigma 1
Authors:Stehle, T, Kirchner, E, Dermody, T.S.
Deposit date:2007-01-12
Release date:2007-02-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The Reovirus Sigma1 Aspartic Acid Sandwich: A TRIMERIZATION MOTIF POISED FOR CONFORMATIONAL CHANGE.
J.Biol.Chem., 282, 2007
1PJN
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BU of 1pjn by Molmil
Mouse Importin alpha-bipartite NLS N1N2 from Xenopus laevis phosphoprotein Complex
Descriptor: Histone-binding protein N1/N2, Importin alpha-2 subunit
Authors:Fontes, M.R.M, Teh, T, Jans, D, Brinkworth, R.I, Kobe, B.
Deposit date:2003-06-03
Release date:2003-08-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha
J.Biol.Chem., 278, 2003
1PJM
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BU of 1pjm by Molmil
Mouse Importin alpha-bipartite NLS from human retinoblastoma protein Complex
Descriptor: Importin alpha-2 subunit, Retinoblastoma-associated protein
Authors:Fontes, M.R.M, Teh, T, Jans, D, Brinkworth, R.I, Kobe, B.
Deposit date:2003-06-03
Release date:2003-08-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha
J.Biol.Chem., 278, 2003
1Q1S
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BU of 1q1s by Molmil
Mouse Importin alpha- phosphorylated SV40 CN peptide complex
Descriptor: Importin alpha-2 subunit, Large T antigen
Authors:Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B.
Deposit date:2003-07-22
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375, 2003
1Q1T
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BU of 1q1t by Molmil
Mouse Importin alpha: non-phosphorylated SV40 CN peptide complex
Descriptor: Importin alpha-2 subunit, Large T antigen
Authors:Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B.
Deposit date:2003-07-22
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375, 2003
1EJY
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BU of 1ejy by Molmil
MOUSE IMPORTIN ALPHA-NUCLEOPLASMIN NLS PEPTIDE COMPLEX
Descriptor: IMPORTIN ALPHA, NUCLEOPLASMIN NLS PEPTIDE
Authors:Fontes, M.R, Teh, T, Kobe, B.
Deposit date:2000-03-05
Release date:2000-04-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha.
J.Mol.Biol., 297, 2000
1EJL
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BU of 1ejl by Molmil
MOUSE IMPORTIN ALPHA-SV40 LARGE T ANTIGEN NLS PEPTIDE COMPLEX
Descriptor: IMPORTIN ALPHA, SV40 LARGE T ANTIGEN NLS PEPTIDE
Authors:Fontes, M.R, Teh, T, Kobe, B.
Deposit date:2000-03-03
Release date:2000-04-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha.
J.Mol.Biol., 297, 2000
1IQ1
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BU of 1iq1 by Molmil
CRYSTAL STRUCTURE OF THE IMPORTIN-ALPHA(44-54)-IMPORTIN-ALPHA(70-529) COMPLEX
Descriptor: IMPORTIN ALPHA-2 SUBUNIT
Authors:Catimel, B, Teh, T, Fontes, M.R.M, Jennings, I.G, Kobe, B.
Deposit date:2001-05-28
Release date:2001-11-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Biophysical characterization of interactions involving importin-alpha during nuclear import.
J.Biol.Chem., 276, 2001
2OPC
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BU of 2opc by Molmil
Structure of Melampsora lini avirulence protein, AvrL567-A
Descriptor: AvrL567-A, COBALT (II) ION, IMIDAZOLE
Authors:Guncar, G, Wang, C.I, Forwood, J.K, Teh, T, Catanzariti, A.M, Ellis, J.G, Dodds, P.N, Kobe, B.
Deposit date:2007-01-29
Release date:2007-03-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:The use of Co2+ for crystallization and structure determination, using a conventional monochromatic X-ray source, of flax rust avirulence protein.
Acta Crystallogr.,Sect.F, 63, 2007
2QVT
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BU of 2qvt by Molmil
Structure of Melampsora lini avirulence protein, AvrL567-D
Descriptor: AvrL567-D
Authors:Guncar, G, Wang, C.I, Forwood, J.K, Teh, T, Catanzariti, A.M, Lawrence, G, Schirra, H.J, Anderson, P.A, Ellis, J.G, Dodds, P.N, Kobe, B.
Deposit date:2007-08-08
Release date:2007-10-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystal structures of flax rust avirulence proteins AvrL567-A and -D reveal details of the structural basis for flax disease resistance specificity.
Plant Cell, 19, 2007
4GU4
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BU of 4gu4 by Molmil
Crystal structure of the T1L reovirus attachment protein sigma1 in complex with alpha-2,3-sialyllactose
Descriptor: N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Outer capsid protein sigma-1
Authors:Reiss, K, Stehle, T.
Deposit date:2012-08-29
Release date:2012-12-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The GM2 Glycan Serves as a Functional Coreceptor for Serotype 1 Reovirus.
Plos Pathog., 8, 2012
5IVO
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BU of 5ivo by Molmil
BC2 nanobody
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, BC2-nanobody
Authors:Braun, M.B, Stehle, T.
Deposit date:2016-03-21
Release date:2016-04-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Peptides in headlock - a novel high-affinity and versatile peptide-binding nanobody for proteomics and microscopy.
Sci Rep, 6, 2016
7OJ7
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BU of 7oj7 by Molmil
Crystal structure of human coxsackievirus A24v in complex with a pentavalent N-acetylneuraminic acid conjugate
Descriptor: CALCIUM ION, CHLORIDE ION, Capsid protein VP1, ...
Authors:Zocher, G, Stehle, T.
Deposit date:2021-05-14
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Exploring the Effect of Structure-Based Scaffold Hopping on the Inhibition of Coxsackievirus A24v Transduction by Pentavalent N-Acetylneuraminic Acid Conjugates.
Int J Mol Sci, 22, 2021
3N0I
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BU of 3n0i by Molmil
Crystal Structure of Ad37 fiber knob in complex with GD1a oligosaccharide
Descriptor: Fiber, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ZINC ION
Authors:Nilsson, E.C, Storm, R.J, Bauer, J, Johansson, S.M.C, Lookene, A, Angstroem, J, Hedenstroem, M, Fraengsmyr, L, Rinaldi, S, Willison, H, Domelloef, F.P, Stehle, T, Arnberg, N.
Deposit date:2010-05-14
Release date:2010-12-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis.
NAT.MED. (N.Y.), 17, 2011
4Q4V
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BU of 4q4v by Molmil
Crystal structure of Coxsackievirus A24v
Descriptor: Coxsackievirus capsid protein VP1, Coxsackievirus capsid protein VP2, Coxsackievirus capsid protein VP3, ...
Authors:Zocher, G, Stehle, T.
Deposit date:2014-04-15
Release date:2014-11-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A sialic Acid binding site in a human picornavirus.
Plos Pathog., 10, 2014
7ZH8
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BU of 7zh8 by Molmil
DYRK1a in Complex with a Bromo-Triazolo-Pyridine
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-bromanyl-3H-[1,2,3]triazolo[4,5-b]pyridine, CHLORIDE ION, ...
Authors:Dammann, M, Stahlecker, J, Stehle, T, Boeckler, F.M.
Deposit date:2022-04-05
Release date:2022-11-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Screening of a Halogen-Enriched Fragment Library Leads to Unconventional Binding Modes.
J.Med.Chem., 65, 2022
8A92
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BU of 8a92 by Molmil
p53-Y220C Core Domain in Complex with a Bromo-trifluoro-pyrazole-amine
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-bromanyl-5-(trifluoromethyl)-1H-pyrazol-3-amine, Cellular tumor antigen p53, ...
Authors:Stahlecker, J, Braun, M.B, Stehle, T, Boeckler, F.M.
Deposit date:2022-06-27
Release date:2022-11-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Revisiting a challenging p53 binding site: a diversity-optimized HEFLib reveals diverse binding modes in T-p53C-Y220C.
Rsc Med Chem, 13, 2022
4Q4X
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BU of 4q4x by Molmil
Crystal structure of Coxsackievirus A24v soaked with 6'-Sialyllactose (6SL)
Descriptor: CALCIUM ION, CHLORIDE ION, Coxsackievirus capsid protein VP1, ...
Authors:Zocher, G, Stehle, T.
Deposit date:2014-04-15
Release date:2014-11-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A sialic Acid binding site in a human picornavirus.
Plos Pathog., 10, 2014
4Q4Y
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BU of 4q4y by Molmil
Crystal structure of Coxsackievirus A24v soaked with Disialyllacto-N-tetraose (DSLNT)
Descriptor: CALCIUM ION, CHLORIDE ION, Coxsackievirus capsid protein VP1, ...
Authors:Zocher, G, Stehle, T.
Deposit date:2014-04-15
Release date:2014-11-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:A sialic Acid binding site in a human picornavirus.
Plos Pathog., 10, 2014
4WDY
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BU of 4wdy by Molmil
JC Polyomavirus VP1 five-fold pore mutant N221Q
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein VP1
Authors:Stroh, L.J, Stehle, T.
Deposit date:2014-09-09
Release date:2015-02-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Modulation of a Pore in the Capsid of JC Polyomavirus Reduces Infectivity and Prevents Exposure of the Minor Capsid Proteins.
J.Virol., 89, 2015
4WE0
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BU of 4we0 by Molmil
JC Polyomavirus VP1 five-fold pore mutant P223M
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein VP1
Authors:Stroh, L.J, Stehle, T.
Deposit date:2014-09-09
Release date:2015-02-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Modulation of a Pore in the Capsid of JC Polyomavirus Reduces Infectivity and Prevents Exposure of the Minor Capsid Proteins.
J.Virol., 89, 2015
5C1J
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BU of 5c1j by Molmil
Crystal Structure of native (reduced) CorB
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CorB
Authors:Zocher, G, Vilstrup, J, Stehle, T.
Deposit date:2015-06-14
Release date:2016-06-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis of head to head polyketide fusion by CorB.
Chem Sci, 6, 2015
1JV2
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BU of 1jv2 by Molmil
CRYSTAL STRUCTURE OF THE EXTRACELLULAR SEGMENT OF INTEGRIN ALPHAVBETA3
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Xiong, J.P, Stehle, T, Diefenbach, B, Zhang, R, Dunker, R, Scott, D, Joachimiak, A, Goodman, S.L, Arnaout, M.A.
Deposit date:2001-08-28
Release date:2001-10-17
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the extracellular segment of integrin alpha Vbeta3.
Science, 294, 2001
7ZIP
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BU of 7zip by Molmil
JC Polyomavirus VP1 in complex with 3'-Sialyllactose glycomacromolecules (aliphatic linker)
Descriptor: Major capsid protein VP1, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Freytag, J, Mueller, J.C, Stehle, T.
Deposit date:2022-04-08
Release date:2022-12-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Synthesis of Homo- and Heteromultivalent Fucosylated and Sialylated Oligosaccharide Conjugates via Preactivated N -Methyloxyamine Precision Macromolecules and Their Binding to Polyomavirus Capsid Proteins.
Biomacromolecules, 23, 2022

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数据于2024-06-19公开中

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