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Structural Analysis of a probable eukaryotic D-amino acid tRNA deacylase
Descriptor:	Probable eukaryotic D-amino acid tRNA deacylase, LMAJ005534AAA
Authors:	Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2004-05-20
Release date:	2004-06-08
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.93 Å)
Cite:	Structural analysis of LMAJ005534AAA, a probable eukaryotic D-amino acid tRNA deacylase from Leishmania major To be Published

1SYR

Initial Structural Analysis of Plasmodium falciparum thioredoxin
Descriptor:	thioredoxin
Authors:	Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2004-04-01
Release date:	2004-04-13
Last modified:	2018-01-31
Method:	X-RAY DIFFRACTION (2.95 Å)
Cite:	Initial Structural Analysis of Plasmodium falciparum thioredoxin To be Published

1TQX

Crystal Structure of Pfal009167 A Putative D-Ribulose 5-Phosphate 3-Epimerase from P.falciparum
Descriptor:	D-ribulose-5-phosphate 3-epimerase, putative, SULFATE ION, ...
Authors:	Caruthers, J, Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2004-06-18
Release date:	2004-12-21
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Structure of a ribulose 5-phosphate 3-epimerase from Plasmodium falciparum. Proteins, 62, 2006

2A0M

Arginase superfamily protein from Trypanosoma cruzi
Descriptor:	ARGINASE SUPERFAMILY PROTEIN, CHLORIDE ION
Authors:	Arakaki, T.L, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2005-06-16
Release date:	2005-07-05
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.603 Å)
Cite:	Structural genomics of pathogenic protozoa: an overview. Methods Mol.Biol., 426, 2008

1XQ7

Cyclophilin from Trypanosoma cruzi bound to cyclosporin A
Descriptor:	CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
Authors:	Caruthers, J.M, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2004-10-11
Release date:	2004-12-21
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.07 Å)
Cite:	Cyclophilin from Trypanosoma Cruzi Bound to Cyclosporin A To be Published

1XTP

Structural Analysis of Leishmania major LMAJ004091AAA, a SAM-dependent methyltransferase of the DUF858/Pfam05891 family
Descriptor:	LMAJ004091AAA, S-ADENOSYL-L-HOMOSELENOCYSTEINE
Authors:	Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2004-10-22
Release date:	2004-11-09
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (1.94 Å)
Cite:	Structural Analysis of Leishmania major LMAJ004091AAA To be Published

1X6O

Structural Analysis of Leishmania braziliensis eukaryotic initiation factor 5a
Descriptor:	DI(HYDROXYETHYL)ETHER, eukaryotic initiation factor 5a
Authors:	Bosch, J, Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2004-08-11
Release date:	2004-08-24
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Structural Analysis of Leishmania braziliensis eukaryotic initiation factor 5a To be Published

1XIQ

Plasmodium falciparum Nucleoside diphosphate kinase B
Descriptor:	Nucleoside diphosphate kinase B
Authors:	Robien, M.A, Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2004-09-21
Release date:	2004-10-12
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (3.05 Å)
Cite:	Crystal structure of Nucleoside diphosphate kinase B from Plasmodium falciparum To be Published

4DS2

Ubiquitin conjugating enzyme (putative) from Trypanosoma cruzi
Descriptor:	Ubiquitin-conjugating enzyme E2, putative
Authors:	Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2012-02-17
Release date:	2012-02-29
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.63 Å)
Cite:	Ubiquitin conjugating enzyme (putative) from Trypanosoma cruzi To be Published

1YJ8

Initial structural analysis of Plasmodium falciparum Glycerol-3-phosphate dehydrogenase
Descriptor:	glycerol-3-phosphate dehydrogenase
Authors:	Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2005-01-13
Release date:	2005-02-01
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2.85 Å)
Cite:	Initial structural analysis of Plasmodium falciparum Glycerol-3-phosphate dehydrogenase To be Published

3BJE

Crystal structure of Trypanosoma brucei nucleoside phosphorylase shows uridine phosphorylase activity
Descriptor:	1-O-phosphono-alpha-D-ribofuranose, CALCIUM ION, Nucleoside phosphorylase, ...
Authors:	Larson, E.T, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2007-12-03
Release date:	2007-12-18
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.44 Å)
Cite:	The Crystal Structure and Activity of a Putative Trypanosomal Nucleoside Phosphorylase Reveal It to be a Homodimeric Uridine Phosphorylase J.Mol.Biol., 396, 2010

1VJQ

Designed protein based on backbone conformation of procarboxypeptidase-A (1AYE) with sidechains chosen for maximal predicted stability.
Descriptor:	designed protein
Authors:	Merritt, E.A, Baker, D, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2004-03-19
Release date:	2004-03-30
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (2.098 Å)
Cite:	Designed protein based on backbone conformation of procarboxypeptidase-A (1AYE) with sidechains chosen for maximal predicted stability. To be Published

3BWC

Crystal structure of spermidine synthase from Trypanosoma cruzi in complex with SAM at 2.3 A resolution
Descriptor:	BETA-MERCAPTOETHANOL, S-ADENOSYLMETHIONINE, Spermidine synthase
Authors:	Bosch, J, Arakaki, T.L, Le Trong, I, Merritt, E.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2008-01-09
Release date:	2008-04-01
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Crystal structure of spermidine synthase from Trypanosoma cruzi. To be Published

1ZSO

Hypothetical protein from plasmodium falciparum
Descriptor:	hypothetical protein
Authors:	Holmes, M.A, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2005-05-24
Release date:	2005-06-07
Last modified:	2017-10-11
Method:	X-RAY DIFFRACTION (2.17 Å)
Cite:	Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum. Acta Crystallogr.,Sect.F, 62, 2006

3C61

Crystal structure of dihydroorotate dehydrogenase from Leishmania donovani
Descriptor:	(2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, AZIDE ION, CHLORIDE ION, ...
Authors:	Arakaki, T.L, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2008-02-01
Release date:	2008-02-26
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Dihydroorotate dehydrogenase from Leishmania donovani. To be Published

3S4O

Protein Tyrosine Phosphatase (putative) from Leishmania major
Descriptor:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Protein tyrosine phosphatase-like protein, THIOSULFATE
Authors:	Merritt, E.A, Arakaki, T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP), Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2011-05-19
Release date:	2011-06-15
Last modified:	2017-11-08
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Protein Tyrosine Phosphatase from Leishmania major To be Published

2PGF

Crystal structure of adenosine deaminase from Plasmodium vivax in complex with adenosine
Descriptor:	ACETONITRILE, ADENOSINE, ZINC ION, ...
Authors:	Larson, E.T, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2007-04-09
Release date:	2007-04-24
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (1.89 Å)
Cite:	Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity. J.Mol.Biol., 381, 2008

2PGR

Crystal structure of adenosine deaminase from Plasmodium vivax in complex with pentostatin
Descriptor:	2'-DEOXYCOFORMYCIN, ACETONITRILE, ZINC ION, ...
Authors:	Larson, E.T, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2007-04-10
Release date:	2007-04-24
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity. J.Mol.Biol., 381, 2008

1SQ6

Plasmodium falciparum homolog of Uridine phosphorylase/Purine nucleoside phosphorylase
Descriptor:	SULFATE ION, uridine phosphorylase, putative
Authors:	Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2004-03-17
Release date:	2004-04-06
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Structures of Plasmodium falciparum purine nucleoside phosphorylase complexed with sulfate and its natural substrate inosine. Acta Crystallogr.,Sect.D, 61, 2005

1XN4

PUTATIVE MAR1 RIBONUCLEASE FROM LEISHMANIA MAJOR
Descriptor:	ribonuclease MAR1
Authors:	Caruthers, J, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2004-10-04
Release date:	2004-10-12
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (3.8 Å)
Cite:	Crystal structures and proposed structural/functional classification of three protozoan proteins from the isochorismatase superfamily. Protein Sci., 14, 2005

3CSS

Crystal structure of 6-phosphogluconolactonase from Leishmania guyanensis
Descriptor:	6-phosphogluconolactonase, PHOSPHATE ION
Authors:	Arakaki, T.L, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2008-04-10
Release date:	2008-04-22
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Optimal description of a protein structure in terms of multiple groups undergoing TLS motion. Acta Crystallogr.,Sect.D, 62, 2006

3CXM

Leishmania naiffi uracil-DNA glycosylase in complex with 5-bromouracil
Descriptor:	5-bromopyrimidine-2,4(1H,3H)-dione, BROMIDE ION, GLYCEROL, ...
Authors:	Larson, E.T, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2008-04-24
Release date:	2008-05-06
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Structures of Leishmania naiffi uracil-DNA glycosylase in complex with several ligands identified with fragment cocktail crystallography. To be Published

1X9G

PUTATIVE MAR1 RIBONUCLEASE FROM LEISHMANIA DONOVANI
Descriptor:	PUTATIVE MAR1
Authors:	Caruthers, J, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2004-08-20
Release date:	2004-09-07
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2.41 Å)
Cite:	Crystal structures and proposed structural/functional classification of three protozoan proteins from the isochorismatase superfamily. Protein Sci., 14, 2005

1R75

Leishmania major hypothetical protein
Descriptor:	GLYCEROL, hypothetical protein
Authors:	Han, G.W, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2003-10-17
Release date:	2003-12-02
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.86 Å)
Cite:	LEISHMANIA MAJOR HYPOTHETICAL PROTEIN To be Published

1YZV

HYPOTHETICAL PROTEIN FROM TRYPANOSOMA CRUZI
Descriptor:	HYPOTHETICAL PROTEIN, SULFATE ION
Authors:	Caruthers, J, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2005-02-28
Release date:	2005-03-08
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2.001 Å)
Cite:	Crystal structures and proposed structural/functional classification of three protozoan proteins from the isochorismatase superfamily. Protein Sci., 14, 2005

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