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8QYW
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BU of 8qyw by Molmil
Human Pyridoxine-5'-phosphate oxidase mutant R225H
Descriptor: FLAVIN MONONUCLEOTIDE, PHOSPHATE ION, Pyridoxine-5'-phosphate oxidase
Authors:Antonelli, L, Ilari, A, Fiorillo, A.
Deposit date:2023-10-26
Release date:2024-02-07
Method:X-RAY DIFFRACTION (2.746 Å)
Cite:Identification of the pyridoxal 5'-phosphate allosteric site in human pyridox(am)ine 5'-phosphate oxidase.
Protein Sci., 33, 2024
7PQ9
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BU of 7pq9 by Molmil
Crystal structure of Bacillus clausii pdxR at 2.8 Angstroms resolution
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Vivoli Vega, M, Isupov, M.N, Harmer, N.
Deposit date:2021-09-16
Release date:2022-09-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR.
Nucleic Acids Res., 51, 2023
6FL5
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BU of 6fl5 by Molmil
Structure of human SHMT1-H135N-R137A-E168N mutant at 3.6 Ang. resolution
Descriptor: CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase, ...
Authors:Giardina, G, Cutruzzola, F, Lucchi, R.
Deposit date:2018-01-25
Release date:2018-10-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells.
FEBS J., 285, 2018
8PUM
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BU of 8pum by Molmil
Tha1 L-threonine aldolase (mouse), monoclinic form (C2)
Descriptor: L-threonine aldolase, SODIUM ION
Authors:Battistutta, R, Fornasier, E, Giachin, G.
Deposit date:2023-07-17
Release date:2024-03-20
Last modified:2024-10-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:One substrate many enzymes virtual screening uncovers missing genes of carnitine biosynthesis in human and mouse.
Nat Commun, 15, 2024
8PUS
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BU of 8pus by Molmil
Tha1 L-threonine aldolase (mouse), orthorhombic form (F222)
Descriptor: L-threonine aldolase
Authors:Battistutta, R, Fornasier, E, Giachin, G.
Deposit date:2023-07-17
Release date:2024-03-20
Last modified:2024-10-02
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:One substrate many enzymes virtual screening uncovers missing genes of carnitine biosynthesis in human and mouse.
Nat Commun, 15, 2024
7Q00
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BU of 7q00 by Molmil
Crystal structure of serine hydroxymethyltransferase, isoform 4 from Arabidopsis thaliana (SHM4)
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Serine hydroxymethyltransferase 4
Authors:Ruszkowski, M, Sekula, B.
Deposit date:2021-10-13
Release date:2022-08-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Arabidopsis thaliana serine hydroxymethyltransferases: functions, structures, and perspectives.
Plant Physiol Biochem., 187, 2022
7PZZ
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BU of 7pzz by Molmil
Crystal structure of serine hydroxymethyltransferase, isoform 2 from Arabidopsis thaliana (SHM2)
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ...
Authors:Ruszkowski, M, Sekula, B.
Deposit date:2021-10-13
Release date:2022-08-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Arabidopsis thaliana serine hydroxymethyltransferases: functions, structures, and perspectives.
Plant Physiol Biochem., 187, 2022
7QPE
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BU of 7qpe by Molmil
Crystal structure of serine hydroxymethyltransferase, isoform 6 from Arabidopsis thaliana (SHM6)
Descriptor: NITRATE ION, Serine hydroxymethyltransferase 6
Authors:Ruszkowski, M, Grzechowiak, M, Sekula, B.
Deposit date:2022-01-04
Release date:2022-08-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Arabidopsis thaliana serine hydroxymethyltransferases: functions, structures, and perspectives.
Plant Physiol Biochem., 187, 2022
7QX8
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BU of 7qx8 by Molmil
Crystal structure of serine hydroxymethyltransferase, isoform 7 from Arabidopsis thaliana (SHM7)
Descriptor: Serine hydroxymethyltransferase 7
Authors:Ruszkowski, M, Grzechowiak, M, Sekula, B.
Deposit date:2022-01-26
Release date:2022-08-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Arabidopsis thaliana serine hydroxymethyltransferases: functions, structures, and perspectives.
Plant Physiol Biochem., 187, 2022
8T1R
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BU of 8t1r by Molmil
Crystal structure of human CPSF73 catalytic segment in complex with compound 2
Descriptor: 3-[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1,3,5-trien-5-yl]-~{N}-[3-(3-methoxyphenyl)phenyl]propanamide, CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 3, ...
Authors:Huang, J, Tong, L.
Deposit date:2023-06-02
Release date:2023-11-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3.
Cell Chem Biol, 31, 2024
8T1Q
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BU of 8t1q by Molmil
Crystal structure of human CPSF73 catalytic segment in complex with compound 1
Descriptor: 3-[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1,3,5-trien-5-yl]-~{N}-[3-(4-ethanoylphenyl)phenyl]propanamide, CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 3, ...
Authors:Huang, J, Tong, L.
Deposit date:2023-06-02
Release date:2023-11-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3.
Cell Chem Biol, 31, 2024
1TRH
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BU of 1trh by Molmil
TWO CONFORMATIONAL STATES OF CANDIDA RUGOSA LIPASE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, LIPASE
Authors:Grochulski, P, Cygler, M.
Deposit date:1993-11-18
Release date:1994-01-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Two conformational states of Candida rugosa lipase.
Protein Sci., 3, 1994
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