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2W0S
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BU of 2w0s by Molmil
Crystal structure of vaccinia virus thymidylate kinase bound to brivudin-5'-monophosphate
Descriptor: (E)-5-(2-BROMOVINYL)-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, MAGNESIUM ION, SULFATE ION, ...
Authors:Caillat, C, Topalis, D, Agrofoglio, L.A, Pochet, S, Balzarini, J, Deville-Bonne, D, Meyer, P.
Deposit date:2008-10-08
Release date:2008-10-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.918 Å)
Cite:Crystal Structure of Poxvirus Thymidylate Kinase: An Unexpected Dimerization Has Implications for Antiviral Therapy
Proc.Natl.Acad.Sci.USA, 105, 2008
2FEP
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BU of 2fep by Molmil
Structure of truncated CcpA in complex with P-Ser-HPr and Sulfate ions
Descriptor: Catabolite control protein A, Phosphocarrier protein HPr, SULFATE ION
Authors:Chaptal, V, Gueguen-Chaignon, V, Poncet, S, Lecampion, C, Meyer, P, Deutscher, J, Galinier, A, Nessler, S.
Deposit date:2005-12-16
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural analysis of B. subtilis CcpA effector binding site.
Proteins, 64, 2006
2LSV
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BU of 2lsv by Molmil
The NMR high resolution structure of yeast Tah1 in complex with the Hsp90 C-terminal tail
Descriptor: ATP-dependent molecular chaperone HSP82, TPR repeat-containing protein associated with Hsp90
Authors:Back, R, Dominguez, C, Rothe, B, Bobo, C, Beaufils, C, Morera, S, Meyer, P, Charpentier, B, Branlant, C, Allain, F, Manival, X.
Deposit date:2012-05-07
Release date:2013-05-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:High-Resolution Structural Analysis Shows How Tah1 Tethers Hsp90 to the R2TP Complex.
Structure, 21, 2013
2LSU
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BU of 2lsu by Molmil
The NMR high resolution structure of yeast Tah1 in a free form
Descriptor: TPR repeat-containing protein associated with Hsp90
Authors:Back, R, Dominguez, C, Rothe, B, Bobo, C, Beaufils, C, Morera, S, Meyer, P, Charpentier, B, Branlant, C, Allain, F, Manival, X.
Deposit date:2012-05-07
Release date:2013-05-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:High-Resolution Structural Analysis Shows How Tah1 Tethers Hsp90 to the R2TP Complex.
Structure, 21, 2013
1EHW
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BU of 1ehw by Molmil
HUMAN NUCLEOSIDE DIPHOSPHATE KINASE 4
Descriptor: NUCLEOSIDE DIPHOSPHATE KINASE, SULFATE ION
Authors:Milon, L, Meyer, P, Chiadmi, M, Munier, A, Johansson, M, Karlsson, A, Lascu, I, Capeau, J, Janin, J, Lacombe, M.-L.
Deposit date:2000-02-23
Release date:2000-05-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinase.
J.Biol.Chem., 275, 2000
2XX3
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BU of 2xx3 by Molmil
HUMAN THYMIDYLATE KINASE COMPLEXED WITH thymidine butenyl phosphonate monophosphate and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, N1-[(E)-4-DIHYDROXYPHOSPHONYL-BUT-2-ENYL]-THYMINE, ...
Authors:Caillat, C, Meyer, P.
Deposit date:2010-11-08
Release date:2011-12-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Novel Antiviral C5-Substituted Pyrimidine Acyclic Nucleoside Phosphonates Selected as Human Thymidylate Kinase Substrates.
J.Med.Chem., 54, 2011
1F6T
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BU of 1f6t by Molmil
STRUCTURE OF THE NUCLEOSIDE DIPHOSPHATE KINASE/ALPHA-BORANO(RP)-TDP.MG COMPLEX
Descriptor: 2*-DEOXY-THYMIDINE-5*-ALPHA BORANO DIPHOSPHATE (ISOMER RP), MAGNESIUM ION, PROTEIN (NUCLEOSIDE DIPHOSPHATE KINASE)
Authors:Guerreiro, C, Boretto, J, Janin, J, Veron, M, Canard, B, Schneider, B, Sarfati, S, Deville-Bonne, D.
Deposit date:2000-06-23
Release date:2000-09-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis for activation of alpha-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase.
EMBO J., 19, 2000
6FDP
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BU of 6fdp by Molmil
NMR structure of the second TPR domain of the human RPAP3 protein in complex with HSP90 peptide DTSRMEEVD
Descriptor: Heat shock protein HSP 90-alpha, RNA polymerase II-associated protein 3
Authors:Quinternet, M, Chagot, M.E, Manival, X.
Deposit date:2017-12-26
Release date:2018-08-01
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex.
Structure, 26, 2018
6FD7
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BU of 6fd7 by Molmil
NMR structure of the first TPR domain of the human RPAP3 protein
Descriptor: RNA polymerase II-associated protein 3
Authors:Quinternet, M, Chagot, M.E, Manival, X.
Deposit date:2017-12-22
Release date:2018-08-01
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex.
Structure, 26, 2018
6FDT
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BU of 6fdt by Molmil
NMR structure of the second TPR domain of the human RPAP3 protein in complex with HSP70 peptide SGPTIEEVD
Descriptor: Heat shock 70 kDa protein 1B, RNA polymerase II-associated protein 3
Authors:Quinternet, M, Chagot, M.E, Manival, X.
Deposit date:2017-12-26
Release date:2018-08-01
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex.
Structure, 26, 2018
1US7
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BU of 1us7 by Molmil
Complex of Hsp90 and P50
Descriptor: HEAT SHOCK PROTEIN HSP82, HSP90 CO-CHAPERONE CDC37
Authors:Roe, S.M, Ali, M.M.U, Pearl, L.H.
Deposit date:2003-11-20
Release date:2004-01-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Mechanism of Hsp90 Regulation by the Protein Kinase-Specific Cochaperone p50(Cdc37)
Cell(Cambridge,Mass.), 116, 2004
2MNJ
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BU of 2mnj by Molmil
NMR solution structure of the yeast Pih1 and Tah1 C-terminal domains complex
Descriptor: Protein interacting with Hsp90 1, TPR repeat-containing protein associated with Hsp90
Authors:Quinternet, M, Jacquemin, C, Charpentier, B, Manival, X.
Deposit date:2014-04-08
Release date:2015-08-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure/Function Analysis of Protein-Protein Interactions Developed by the Yeast Pih1 Platform Protein and Its Partners in Box C/D snoRNP Assembly.
J.Mol.Biol., 427, 2015
2CGE
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BU of 2cge by Molmil
Crystal structure of an Hsp90-Sba1 closed chaperone complex
Descriptor: ATP-DEPENDENT MOLECULAR CHAPERONE HSP82
Authors:Ali, M.M.U, Roe, S.M, Prodromou, C, Pearl, L.H.
Deposit date:2006-03-01
Release date:2006-04-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of an Hsp90-Nucleotide-P23/Sba1 Closed Chaperone Complex
Nature, 440, 2006
2CG9
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BU of 2cg9 by Molmil
Crystal structure of an Hsp90-Sba1 closed chaperone complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, CO-CHAPERONE PROTEIN SBA1
Authors:Ali, M.M.U, Roe, S.M, Prodromou, C, Pearl, L.H.
Deposit date:2006-03-01
Release date:2006-04-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of an Hsp90-Nucleotide-P23/Sba1 Closed Chaperone Complex
Nature, 440, 2006
2AK7
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BU of 2ak7 by Molmil
structure of a dimeric P-Ser-Crh
Descriptor: HPr-like protein crh, SULFATE ION
Authors:Chaptal, V, Gueguen-Chaignon, V, Poncet, S, Lecampion, C, Lariviere, L, Meyer, P, Galinier, A, Deutscher, J, Nessler, S, Morera, S.
Deposit date:2005-08-03
Release date:2006-06-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of a domain-swapped dimer of Ser46-phosphorylated Crh from Bacillus subtilis.
Proteins, 63, 2006
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