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SARS-CoV-2 Spike NTD in complex with neutralizing Fab SARS2-57 (local refinement)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-57 Fv heavy chain, ...
Authors:	Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2021-11-21
Release date:	2022-11-23
Last modified:	2023-02-01
Method:	ELECTRON MICROSCOPY (3.13 Å)
Cite:	A protective antibody targeting the N-terminal domain of SARS-CoV-2 spike recognizes most emerging variants To Be Published

7SWX

SARS-CoV-2 Spike in complex with neutralizing Fab SARS2-57 (three down conformation)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-57 Fv heavy chain, ...
Authors:	Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2021-11-21
Release date:	2022-11-23
Last modified:	2023-02-01
Method:	ELECTRON MICROSCOPY (3.13 Å)
Cite:	A protective antibody targeting the N-terminal domain of SARS-CoV-2 spike recognizes most emerging variants To Be Published

8UFB

Eastern equine encephalitis virus (PE-6) VLP in complex with full-length VLDLR (asymmetric unit)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ...
Authors:	Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2023-10-04
Release date:	2024-01-17
Last modified:	2024-10-23
Method:	ELECTRON MICROSCOPY (3.89 Å)
Cite:	Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus. Cell, 187, 2024

8UFC

Eastern equine encephalitis virus (PE-6) VLP in complex with VLDLR LA(1-2) (asymmetric unit)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ...
Authors:	Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2023-10-04
Release date:	2024-01-17
Last modified:	2024-10-30
Method:	ELECTRON MICROSCOPY (3.09 Å)
Cite:	Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus. Cell, 187, 2024

8UFA

Eastern equine encephalitis virus (PE-6) VLP (asymmetric unit)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 protein, ...
Authors:	Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2023-10-04
Release date:	2024-01-17
Last modified:	2024-01-31
Method:	ELECTRON MICROSCOPY (2.86 Å)
Cite:	Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus. Cell, 187, 2024

1XAU

STRUCTURE OF THE BTLA ECTODOMAIN
Descriptor:	B- and T-lymphocyte attenuator, CADMIUM ION
Authors:	Nelson, C.A, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
Deposit date:	2004-08-26
Release date:	2004-10-05
Last modified:	2024-10-09
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Structural determinants of herpesvirus entry mediator recognition by murine B and T lymphocyte attenuator. J.Immunol., 180, 2008

8DWW

Chikungunya VLP in complex with neutralizing Fab 506.A08 (asymmetric unit)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 506.A08 heavy chain, 506.A08 light chain, ...
Authors:	Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2022-08-02
Release date:	2023-05-31
Method:	ELECTRON MICROSCOPY (3.13 Å)
Cite:	A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans. Sci Transl Med, 15, 2023

8DWX

Chikungunya VLP in complex with neutralizing Fab 506.C01 (asymmetric unit)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 506.C01 heavy chain, 506.C01 light chain, ...
Authors:	Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2022-08-02
Release date:	2023-05-31
Last modified:	2024-10-23
Method:	ELECTRON MICROSCOPY (3.27 Å)
Cite:	A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans. Sci Transl Med, 15, 2023

8DWY

Chikungunya VLP in complex with neutralizing Fab CHK-265 (asymmetric unit)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, CHK-265 heavy chain, CHK-265 light chain, ...
Authors:	Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2022-08-02
Release date:	2023-05-31
Last modified:	2024-10-16
Method:	ELECTRON MICROSCOPY (3.18 Å)
Cite:	A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans. Sci Transl Med, 15, 2023

4ZLT

Crystal structure of viral chemokine binding protein R17 in complex with CCL3
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 3, Putative uncharacterized protein
Authors:	Lubman, O.Y, Fremont, D.H.
Deposit date:	2015-05-01
Release date:	2015-11-18
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors. Structure, 24, 2016

4ZKQ

Viral chemokine binding protein R17 encoded by rodent gammaherpesvirus Peru ( RHVP)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Putative uncharacterized protein
Authors:	Lubman, O.Y, Fremont, D.H.
Deposit date:	2015-04-30
Release date:	2015-11-18
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.898 Å)
Cite:	Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors. Structure, 24, 2016

8EWF

CryoEM structure of Western equine encephalitis virus VLP in complex with the avian MXRA8 receptor
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Chimeric MXRA8 receptor: D1 from Duck MXRA8 and D2 from Mouse MXRA8, E1 envelope protein, ...
Authors:	Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2022-10-22
Release date:	2023-10-25
Last modified:	2024-10-09
Method:	ELECTRON MICROSCOPY (3.92 Å)
Cite:	Alternate domain repeat usage in an alphavirus entry receptor enables host species expansion To Be Published

5ANY

Electron cryo-microscopy of chikungunya virus in complex with neutralizing antibody Fab CHK265
Descriptor:	E1, E2, FAB, ...
Authors:	Fox, J.M, Long, F, Edeling, M.A, Lin, H, Duijl-Richter, M, Fong, R.H, Kahle, K.M, Smit, J.M, Jin, J, Simmons, G, Doranz, B.J, Crowe, J.E, Fremont, D.H, Rossmann, M.G, Diamond, M.S.
Deposit date:	2015-09-08
Release date:	2015-11-25
Last modified:	2018-10-03
Method:	ELECTRON MICROSCOPY (16.9 Å)
Cite:	Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress. Cell(Cambridge,Mass.), 163, 2015

5FFL

Crystal structure of mouse CD300lf at 1.6 Angstroms resolution.
Descriptor:	(4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CD300 antigen-like family member F, ...
Authors:	Nelson, C.A, Fremont, D.H.
Deposit date:	2015-12-18
Release date:	2016-08-31
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.602 Å)
Cite:	Discovery of a proteinaceous cellular receptor for a norovirus. Science, 353, 2016

6V4O

Structure of human 2E01 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain, Antibody Fab light chain, ...
Authors:	Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2019-11-28
Release date:	2020-10-07
Last modified:	2024-10-23
Method:	ELECTRON MICROSCOPY (2.8 Å)
Cite:	Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective. Immunity, 53, 2020

6V4N

Structure of human 1G05 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain, Antibody Fab light chain, ...
Authors:	Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2019-11-28
Release date:	2020-10-07
Last modified:	2020-10-28
Method:	ELECTRON MICROSCOPY (2.5 Å)
Cite:	Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective. Immunity, 53, 2020

2NZ1

Viral Chemokine Binding Protein M3 From Murine Gammaherpesvirus68 In Complex With The CC-Chemokine CCL2/MCP-1
Descriptor:	Hypothetical protein GAMMAHV.M3, Small inducible cytokine A2
Authors:	Alexander-Brett, J.M, Fremont, D.H.
Deposit date:	2006-11-22
Release date:	2007-12-25
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Dual GPCR and GAG mimicry by the M3 chemokine decoy receptor. J.Exp.Med., 204, 2007

2NYZ

Viral Chemokine Binding Protein M3 From Murine Gammaherpesvirus68 In Complex With The C- Chemokine XCL1
Descriptor:	Hypothetical protein GAMMAHV.M3, Lymphotactin
Authors:	Alexander-Brett, J.M, Fremont, D.H.
Deposit date:	2006-11-21
Release date:	2007-12-25
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Dual GPCR and GAG mimicry by the M3 chemokine decoy receptor. J.Exp.Med., 204, 2007

6W37

STRUCTURE OF THE SARS-CoV-2 ORF7A ENCODED ACCESSORY PROTEIN
Descriptor:	ORF7a protein
Authors:	Nelson, C.A, Minasov, G, Shuvalova, L, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2020-03-09
Release date:	2020-04-29
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (2.9 Å)
Cite:	STRUCTURE OF THE SARS-CoV-2 ORF7A ENCODED ACCESSORY PROTEIN To be published

5KVG

Zika specific antibody, ZV-67, bound to ZIKA envelope DIII
Descriptor:	CHLORIDE ION, ZIKA Envelope DIII, ZV-67 Antibody Fab Heavy Chain, ...
Authors:	Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2016-07-14
Release date:	2016-08-03
Last modified:	2016-08-24
Method:	X-RAY DIFFRACTION (1.4 Å)
Cite:	Structural Basis of Zika Virus-Specific Antibody Protection. Cell, 166, 2016

5KVF

Zika specific antibody, ZV-64, bound to ZIKA envelope DIII
Descriptor:	GLYCEROL, ZV-64 Antibody Fab Heavy Chain, ZV-64 Antibody Fab Light Chain, ...
Authors:	Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2016-07-14
Release date:	2016-08-03
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.4 Å)
Cite:	Structural Basis of Zika Virus-Specific Antibody Protection. Cell, 166, 2016

5KVE

Zika specific antibody, ZV-48, bound to ZIKA envelope DIII
Descriptor:	1,2-ETHANEDIOL, ACETATE ION, Genome polyprotein, ...
Authors:	Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2016-07-14
Release date:	2016-08-10
Last modified:	2019-12-25
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Structural Basis of Zika Virus-Specific Antibody Protection. Cell, 166, 2016

5KVD

Zika specific antibody, ZV-2, bound to ZIKA envelope DIII
Descriptor:	1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SODIUM ION, ...
Authors:	Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2016-07-14
Release date:	2016-08-03
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	Structural Basis of Zika Virus-Specific Antibody Protection. Cell, 166, 2016

3P54

Crystal Structure of the Japanese Encephalitis Virus Envelope Protein, strain SA-14-14-2.
Descriptor:	envelope glycoprotein
Authors:	Luca, V.C, Nelson, C.A, AbiMansour, J.P, Diamond, M.S, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2010-10-07
Release date:	2010-12-08
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (2.097 Å)
Cite:	Crystal structure of the Japanese encephalitis virus envelope protein. J.Virol., 86, 2012

6P6P

Crystal structure of hemagglutinin from influenza virus A/Sichuan/2/1987 (H3N2)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:	Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:	2019-06-04
Release date:	2020-07-01
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (2.31 Å)
Cite:	Crystal structure of hemagglutinin from influenza virus A/Sichuan/2/1987 (H3N2) To Be Published

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