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Crystal Structure of C. elegans cell-death-related nuclease 5(CRN-5)
Descriptor:	Protein C14A4.5, confirmed by transcript evidence
Authors:	Yang, C.-C, Wang, Y.-T, Hsiao, Y.-Y, Doudeva, L.G, Chow, S.Y, Yuan, H.S.
Deposit date:	2009-11-19
Release date:	2010-01-26
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (3.918 Å)
Cite:	Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation Rna, 16, 2010

4Y1H

Crystal structure of K33 linked tri-Ubiquitin
Descriptor:	1,2-ETHANEDIOL, Ubiquitin-40S ribosomal protein S27a
Authors:	Kristariyanto, Y.A, Abdul Rehman, S.A, Choi, S.Y, Ritorto, S, Campbell, D.G, Morrice, N.A, Toth, R, Kulathu, Y.
Deposit date:	2015-02-07
Release date:	2015-03-18
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.4 Å)
Cite:	Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations. Biochem.J., 467, 2015

4XYZ

Crystal structure of K33 linked di-Ubiquitin
Descriptor:	1,2-ETHANEDIOL, ACETATE ION, IODIDE ION, ...
Authors:	Kristariyanto, Y.A, Abdul Rehman, S.A, Choi, S.Y, Ritorto, S, Campbell, D.G, Morrice, N.A, Toth, R, Kulathu, Y.
Deposit date:	2015-02-03
Release date:	2015-03-18
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations. Biochem.J., 467, 2015

5XJH

Crystal structure of PETase from Ideonella sakaiensis
Descriptor:	Poly(ethylene terephthalate) hydrolase
Authors:	Joo, S, Kim, K.-J.
Deposit date:	2017-05-01
Release date:	2018-02-14
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (1.54 Å)
Cite:	Structural insight into molecular mechanism of poly(ethylene terephthalate) degradation. Nat Commun, 9, 2018

7BYK

Crystal structure of the Legionella pneumophila LegK7 effector kinase
Descriptor:	LegK7
Authors:	Park, S.C, Kim, T.H, Yoon, S.I.
Deposit date:	2020-04-23
Release date:	2020-12-30
Last modified:	2024-03-27
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Activation of the Legionella pneumophila LegK7 Effector Kinase by the Host MOB1 Protein. J.Mol.Biol., 433, 2020

5F20

Structure of TYK2 with inhibitor 4: 3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{H}-pyrazolo[4,3-c]pyridin-4-one
Descriptor:	3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{H}-pyrazolo[4,3-c]pyridin-4-one, Non-receptor tyrosine-protein kinase TYK2
Authors:	Skene, R.J.
Deposit date:	2015-12-01
Release date:	2016-01-13
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.91 Å)
Cite:	Structure-Based Design and Synthesis of 3-Amino-1,5-dihydro-4H-pyrazolopyridin-4-one Derivatives as Tyrosine Kinase 2 Inhibitors. J.Med.Chem., 59, 2016

5F1Z

Structure of TYK2 with inhibitor 16: 3-azanyl-5-[(2~{S})-3-methylbutan-2-yl]-7-[1-methyl-5-(2-oxidanylpropan-2-yl)pyrazol-3-yl]-1~{H}-pyrazolo[4,3-c]pyridin-4-one
Descriptor:	3-azanyl-5-[(2~{S})-3-methylbutan-2-yl]-7-[1-methyl-5-(2-oxidanylpropan-2-yl)pyrazol-3-yl]-1~{H}-pyrazolo[4,3-c]pyridin-4-one, Non-receptor tyrosine-protein kinase TYK2
Authors:	Skene, R.J.
Deposit date:	2015-12-01
Release date:	2016-01-13
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Structure-Based Design and Synthesis of 3-Amino-1,5-dihydro-4H-pyrazolopyridin-4-one Derivatives as Tyrosine Kinase 2 Inhibitors. J.Med.Chem., 59, 2016

6IJ6

Crystal structure of PETase S121E, D186H, R280A mutant from Ideonella sakaiensis
Descriptor:	Poly(ethylene terephthalate) hydrolase
Authors:	Joo, S, Kim, K.J.
Deposit date:	2018-10-08
Release date:	2019-09-04
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Rational Protein Engineering of Thermo-Stable PETase from Ideonella sakaiensis for Highly Efficient PET Degradation Acs Catalysis, 9, 2019

6IJ4

Crystal structure of PETase S121E, D186H mutant from Ideonella sakaiensis
Descriptor:	Poly(ethylene terephthalate) hydrolase
Authors:	Joo, S, Kim, K.J.
Deposit date:	2018-10-08
Release date:	2019-09-04
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.86 Å)
Cite:	Rational Protein Engineering of Thermo-Stable PETase from Ideonella sakaiensis for Highly Efficient PET Degradation Acs Catalysis, 9, 2019

6IJ5

Crystal structure of PETase P181A mutant from Ideonella sakaiensis
Descriptor:	Poly(ethylene terephthalate) hydrolase
Authors:	Joo, S, Kim, K.J.
Deposit date:	2018-10-08
Release date:	2019-09-04
Last modified:	2023-11-22
Method:	X-RAY DIFFRACTION (1.72 Å)
Cite:	Rational Protein Engineering of Thermo-Stable PETase from Ideonella sakaiensis for Highly Efficient PET Degradation Acs Catalysis, 9, 2019

6IJ3

Crystal structure of PETase S121D, D186H mutant from Ideonella sakaiensis
Descriptor:	Poly(ethylene terephthalate) hydrolase
Authors:	Joo, S, Kim, K.J.
Deposit date:	2018-10-08
Release date:	2019-09-04
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.4 Å)
Cite:	Rational Protein Engineering of Thermo-Stable PETase from Ideonella sakaiensis for Highly Efficient PET Degradation Acs Catalysis, 9, 2019

5YNS

Crystal structure of PETase R280A mutant from Ideonella sakaiensis
Descriptor:	Poly(ethylene terephthalate) hydrolase
Authors:	Joo, S, Kim, K.-J.
Deposit date:	2017-10-25
Release date:	2018-02-14
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.36 Å)
Cite:	Structural insight into molecular mechanism of poly(ethylene terephthalate) degradation. Nat Commun, 9, 2018

5JKN

Crystal structure of deubiquitinase MINDY-1
Descriptor:	DI(HYDROXYETHYL)ETHER, MERCURY (II) ION, PHOSPHATE ION, ...
Authors:	Abdul Rehman, S.A, Kulathu, Y.
Deposit date:	2016-04-26
Release date:	2016-06-22
Last modified:	2024-05-01
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes. Mol.Cell, 63, 2016

8SX3

10E8-GT10.2 immunogen in complex with human Fab 10E8 and mouse Fab W6-10
Descriptor:	10E8 Fab heavy chain, 10E8 light chain, 10E8-GT10.2 immunogen, ...
Authors:	Huang, J, Ozorowski, G, Ward, A.B.
Deposit date:	2023-05-19
Release date:	2024-05-22
Last modified:	2024-11-06
Method:	ELECTRON MICROSCOPY (4 Å)
Cite:	Vaccination induces broadly neutralizing antibody precursors to HIV gp41. Nat.Immunol., 25, 2024

8U03

Crystal structure of non-glycosylated 10E8-GT10.1 scaffold in complex with a human 10E8 NGS precursor (10E8-NGS-03)
Descriptor:	10E8-GT10.1 epitope scaffold, 10E8-NGS-03 Fab Light Chain, 10E8-NGS-03 Fab heavy chain, ...
Authors:	Irimia, A, Wilson, I.A.
Deposit date:	2023-08-28
Release date:	2024-06-12
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (2.72 Å)
Cite:	Vaccination induces broadly neutralizing antibody precursors to HIV gp41. Nat.Immunol., 25, 2024

8TZN

Crystal structure of 10E8-GT10.2 HIV-1 MPER scaffold in complex with a non-human primate W3-01 Fab
Descriptor:	10E8-GT10.2 MPER scaffold, W3-01 Fab Heavy Chain, W3-01 Fab Light Chain
Authors:	Lee, C.C.D, Wilson, I.A.
Deposit date:	2023-08-27
Release date:	2024-06-12
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (3.11 Å)
Cite:	Vaccination induces broadly neutralizing antibody precursors to HIV gp41. Nat.Immunol., 25, 2024

8TZW

Crystal structure of 10E8-GT4 scaffold in complex with a human 10E8 inferred germline (10E8-iGL1)
Descriptor:	10E8-GT4 epitope scaffold, 10E8-IGL1 Fab Light Chain, 10E8-IGL1 Fab heavy chain
Authors:	Irimia, A, Wilson, I.A.
Deposit date:	2023-08-28
Release date:	2024-06-12
Last modified:	2024-10-09
Method:	X-RAY DIFFRACTION (2.66 Å)
Cite:	Vaccination induces broadly neutralizing antibody precursors to HIV gp41. Nat.Immunol., 25, 2024

8U08

Crystal structure of 10E8-GT11 scaffold in complex with a human 10E8 inferred germline (10E8-iGL1)
Descriptor:	10E8-GT11 epitope scaffold, 10E8-IGL1 heavy chain, 10E8-IGL1 light chain, ...
Authors:	Irimia, A, Wilson, I.A.
Deposit date:	2023-08-28
Release date:	2024-06-12
Last modified:	2024-10-09
Method:	X-RAY DIFFRACTION (1.98 Å)
Cite:	Vaccination induces broadly neutralizing antibody precursors to HIV gp41. Nat.Immunol., 25, 2024

4IKC

Crystal Structure of catalytic domain of PTPRQ
Descriptor:	CHLORIDE ION, Phosphotidylinositol phosphatase PTPRQ, SULFATE ION
Authors:	Yu, K.R, Ryu, S.E, Kim, S.J.
Deposit date:	2012-12-26
Release date:	2013-07-31
Last modified:	2023-11-08
Method:	X-RAY DIFFRACTION (1.56 Å)
Cite:	Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates Acta Crystallogr.,Sect.D, 69, 2013

7JU2

Crystal structure of the monomeric ETV6 PNT domain
Descriptor:	FORMIC ACID, Transcription factor ETV6
Authors:	Gerak, C.A.N, Kolesnikov, M, Murphy, M.E.P, McIntosh, L.P.
Deposit date:	2020-08-19
Release date:	2021-01-20
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.85002184 Å)
Cite:	Biophysical characterization of the ETV6 PNT domain polymerization interfaces. J.Biol.Chem., 296, 2021

5HZ2

Crystal structure of PhaC1 from Ralstonia eutropha
Descriptor:	GLYCEROL, Poly-beta-hydroxybutyrate polymerase, SULFATE ION
Authors:	Kim, J, Kim, K.-J.
Deposit date:	2016-02-02
Release date:	2016-12-07
Last modified:	2017-04-05
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Crystal structure of Ralstonia eutropha polyhydroxyalkanoate synthase C-terminal domain and reaction mechanisms. Biotechnol J, 12, 2017

9EZL

Crystal structure of trehalose synthase mutant N253H from Deinococcus radiodurans
Descriptor:	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, MAGNESIUM ION, ...
Authors:	Ye, L.C, Chen, S.C.
Deposit date:	2024-04-12
Release date:	2024-09-04
Method:	X-RAY DIFFRACTION (2.97 Å)
Cite:	Structural and Mutational Analyses of Trehalose Synthase from Deinococcus radiodurans Reveal the Interconversion of Maltose-Trehalose Mechanism. J.Agric.Food Chem., 72, 2024

5JQS

Crystal structure of deubiquitinase MINDY-1 in complex with Ubiquitin
Descriptor:	1,4-DIETHYLENE DIOXIDE, CHLORIDE ION, Protein FAM63A, ...
Authors:	Abdul Rehman, S.A, Kulathu, Y.
Deposit date:	2016-05-05
Release date:	2016-06-22
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes. Mol.Cell, 63, 2016

3HKM

Crystal Structure of rice(Oryza sativa) Rrp46
Descriptor:	Os03g0854200 protein
Authors:	Yang, C.-C, Wang, Y.-T, Hsiao, Y.-Y, Doudeva, L.G, Yuan, H.S.
Deposit date:	2009-05-25
Release date:	2010-01-26
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (1.9845 Å)
Cite:	Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation Rna, 16, 2010

7NFW

Human 14-3-3 sigma in complex with human Estrogen Receptor alpha peptide
Descriptor:	14-3-3 protein sigma, Estrogen receptor
Authors:	Roversi, P, Falcicchio, M, Doveston, R.
Deposit date:	2021-02-08
Release date:	2021-02-17
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.19 Å)
Cite:	Cooperative stabilisation of 14-3-3 sigma protein-protein interactions via covalent protein modification. Chem Sci, 12, 2021

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Displayed results:	25
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