Search by PDB author

STRUCTURE OF A COMPLEX BETWEEN THE DNA SEQUENCE DCGCGAATTCGCG AND BIS[PIPERIDINO-ETHYL]-FURAMIDINE
Descriptor:	2,5-BIS-[4-[CYCLOPENTA-1,3-DIEN-5-YLAMINO-1-AMINOMETHYL]-PHEN-1-YL]FURAN, 5'-D(CPGPCPGPAPAPTPTPCPGPCPG)-3'
Authors:	Neidle, S, Simpson, I.J.
Deposit date:	2000-02-01
Release date:	2000-02-09
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	A thermodynamic and structural analysis of DNA minor-groove complex formation. J.Mol.Biol., 300, 2000

DNA-DB1879 complex: The DNA sequence 5'-CGCGAATTCGCG-3' presents a binding site for the heterocyclic small molecule (DB1879).
Descriptor:	2-[5-(4-carbamimidoylphenyl)thiophen-2-yl]-1H-indole-6-carboximidamide, DNA (5'-D(CPGPCPGPAPAPTPTPCPGPCPG)-3'), MAGNESIUM ION
Authors:	Ogbonna, E, Fang, Z, Wilson, D.W.
Deposit date:	2020-12-01
Release date:	2021-12-08
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.37 Å)
Cite:	Drug design and DNA structural research inspired by the Neidle laboratory: DNA minor groove binding and transcription factor inhibition by thiophene diamidines. Bioorg.Med.Chem., 68, 2022

DNA-DB818 complex: The DNA sequence 5'-CGCGAATTCGCG-3' presents a binding site for the heterocyclic small molecule (DB818).
Descriptor:	1:(5'-D(CPGPCPGPAPAPTPTPCPGPCPG)-3'), 2-(5-{4-[AMINO(IMINO)METHYL]PHENYL}-2-THIENYL)-1H-BENZIMIDAZOLE-6- CARBOXIMIDAMIDE DIHYDROCHLORIDE, MAGNESIUM ION
Authors:	Ogbonna, E, Fang, Z, Wilson, W.D.
Deposit date:	2020-11-24
Release date:	2021-12-01
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Drug design and DNA structural research inspired by the Neidle laboratory: DNA minor groove binding and transcription factor inhibition by thiophene diamidines. Bioorg.Med.Chem., 68, 2022