2D48
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![BU of 2d48 by Molmil](/molmil-images/mine/2d48) | Crystal structure of the Interleukin-4 variant T13D | Descriptor: | Interleukin-4, SULFATE ION | Authors: | Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D. | Deposit date: | 2005-10-11 | Release date: | 2006-05-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor Bmc Biol., 4, 2006
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2QJB
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![BU of 2qjb by Molmil](/molmil-images/mine/2qjb) | Crystal structure analysis of BMP-2 in complex with BMPR-IA variant IA/IB | Descriptor: | Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA, CHLORIDE ION | Authors: | Kotzsch, A, Mueller, T.D. | Deposit date: | 2007-07-06 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome. J.Biol.Chem., 283, 2008
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2QJA
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![BU of 2qja by Molmil](/molmil-images/mine/2qja) | Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B12 | Descriptor: | Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA | Authors: | Kotzsch, A, Mueller, T.D. | Deposit date: | 2007-07-06 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome. J.Biol.Chem., 283, 2008
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3EVS
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![BU of 3evs by Molmil](/molmil-images/mine/3evs) | Crystal structure of the GDF-5:BMP receptor IB complex. | Descriptor: | Bone morphogenetic protein receptor type-1B, Growth/differentiation factor 5 | Authors: | Kotzsch, A, Mueller, T.D. | Deposit date: | 2008-10-13 | Release date: | 2009-03-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity. Embo J., 28, 2009
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3B5K
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![BU of 3b5k by Molmil](/molmil-images/mine/3b5k) | |
2QJ9
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![BU of 2qj9 by Molmil](/molmil-images/mine/2qj9) | Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B1 | Descriptor: | Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA | Authors: | Kotzsch, A, Mueller, T.D. | Deposit date: | 2007-07-06 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome. J.Biol.Chem., 283, 2008
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2K3G
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![BU of 2k3g by Molmil](/molmil-images/mine/2k3g) | |
2H62
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![BU of 2h62 by Molmil](/molmil-images/mine/2h62) | Crystal structure of a ternary ligand-receptor complex of BMP-2 | Descriptor: | Acvr2b protein, Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA | Authors: | Mueller, T.D. | Deposit date: | 2006-05-30 | Release date: | 2007-04-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor. Bmc Struct.Biol., 7, 2007
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6H41
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![BU of 6h41 by Molmil](/molmil-images/mine/6h41) | |
1HZI
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![BU of 1hzi by Molmil](/molmil-images/mine/1hzi) | INTERLEUKIN-4 MUTANT E9A | Descriptor: | INTERLEUKIN-4, SULFATE ION | Authors: | Hulsmeyer, M, Scheufler, C, Dreyer, M.K. | Deposit date: | 2001-01-25 | Release date: | 2001-08-29 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of interleukin 4 mutant E9A suggests polar steering in receptor-complex formation. Acta Crystallogr.,Sect.D, 57, 2001
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1HIJ
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![BU of 1hij by Molmil](/molmil-images/mine/1hij) | |
1HIK
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![BU of 1hik by Molmil](/molmil-images/mine/1hik) | INTERLEUKIN-4 (WILD-TYPE) | Descriptor: | INTERLEUKIN-4 | Authors: | Mueller, T, Buehner, M. | Deposit date: | 1995-06-01 | Release date: | 1996-01-29 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic resonance models. J.Mol.Biol., 247, 1995
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