3RW6
| Structure of nuclear RNA export factor TAP bound to CTE RNA | Descriptor: | Nuclear RNA export factor 1, constitutive transport element(CTE)of Mason-Pfizer monkey virus RNA | Authors: | Teplova, M, Khin, N.W, Patel, D.J, Izaurralde, E. | Deposit date: | 2011-05-07 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP. Nat.Struct.Mol.Biol., 18, 2011
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1HL6
| A novel mode of RBD-protein recognition in the Y14-mago complex | Descriptor: | CG8781 PROTEIN, MAGO NASHI PROTEIN | Authors: | Fribourg, S, Gatfield, D, Yao, W, Izaurralde, E, Conti, E. | Deposit date: | 2003-03-13 | Release date: | 2003-05-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A Novel Mode of Rbd-Protein Recognition in the Y14-Mago Complex Nat.Struct.Biol., 10, 2003
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6H3Z
| Crystal structure of a C-terminal MIF4G domain in NOT1 | Descriptor: | CCR4-not transcription complex subunit 1, SODIUM ION | Authors: | Raisch, T, Sandmeir, F, Weichenrieder, O, Valkov, E, Izaurralde, E. | Deposit date: | 2018-07-19 | Release date: | 2018-11-07 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural and biochemical analysis of a NOT1 MIF4G-like domain of the CCR4-NOT complex. J. Struct. Biol., 204, 2018
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1JN5
| Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain of TAP-p15 mRNA export factor | Descriptor: | FG-repeat, TAP, p15 | Authors: | Fribourg, S, Braun, I.C, Izaurralde, E, Conti, E. | Deposit date: | 2001-07-23 | Release date: | 2001-10-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor. Mol.Cell, 8, 2001
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1JKG
| Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain of TAP-p15 mRNA nuclear export factor | Descriptor: | TAP, p15 | Authors: | Fribourg, S, Braun, I.C, Izaurralde, E, Conti, E. | Deposit date: | 2001-07-12 | Release date: | 2001-10-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor. Mol.Cell, 8, 2001
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3ZHE
| Structure of the C. elegans SMG5-SMG7 complex | Descriptor: | NONSENSE-MEDIATED MRNA DECAY PROTEIN, PROTEIN SMG-7 | Authors: | Jonas, S, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2012-12-21 | Release date: | 2013-02-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | An Unusual Arrangement of Two 14-3-3-Like Domains in the Smg5-Smg7 Heterodimer is Required for Efficient Nonsense-Mediated Mrna Decay. Genes Dev., 27, 2013
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4A54
| Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6 | Descriptor: | EDC3, MRNA DECAPPING COMPLEX SUBUNIT 2 | Authors: | Fromm, S.A, Truffault, V, Kamenz, J, Braun, J.E, Hoffmann, N.A, Izaurralde, E, Sprangers, R. | Deposit date: | 2011-10-24 | Release date: | 2012-02-01 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Structural Basis of Edc3- and Scd6-Mediated Activation of the Dcp1:Dcp2 Mrna Decapping Complex. Embo J., 31, 2011
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4A53
| Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6 | Descriptor: | EDC3 | Authors: | Fromm, S.A, Truffault, V, Kamenz, J, Braun, J.E, Hoffmann, N.A, Izaurralde, E, Sprangers, R. | Deposit date: | 2011-10-24 | Release date: | 2012-02-01 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Structural Basis of Edc3- and Scd6-Mediated Activation of the Dcp1:Dcp2 Mrna Decapping Complex. Embo J., 31, 2011
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1UW4
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1VYN
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5LSW
| A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cell differentiation protein RCD1 homolog, LD12033p, ... | Authors: | Sgromo, A, Raisch, T, Bawankar, P, Bhandari, D, Chen, Y, Kuzuoglu-Ozturk, D, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2016-09-05 | Release date: | 2017-02-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin. Nat Commun, 8, 2017
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2VXG
| Crystal structure of the conserved C-terminal region of Ge-1 | Descriptor: | CG6181-PA, ISOFORM A | Authors: | Jinek, M, Eulalio, A, Lingel, A, Helms, S, Conti, E, Izaurralde, E. | Deposit date: | 2008-07-04 | Release date: | 2008-09-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The C-Terminal Region of Ge-1 Presents Conserved Structural Features Required for P-Body Localization. RNA, 14, 2008
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5ONA
| Drosophila Bag-of-marbles CBM peptide bound to human CAF40-CNOT1 | Descriptor: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 9, CHLORIDE ION, ... | Authors: | Raisch, T, Sgromo, A, Backhaus, C, Izaurralde, E, Weichenrieder, O. | Deposit date: | 2017-08-03 | Release date: | 2017-12-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | DrosophilaBag-of-marbles directly interacts with the CAF40 subunit of the CCR4-NOT complex to elicit repression of mRNA targets. RNA, 24, 2018
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4BWK
| Structure of Neurospora crassa PAN3 pseudokinase | Descriptor: | PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN-3, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Christie, M, Boland, A, Huntzinger, E, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2013-07-04 | Release date: | 2013-08-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins Mol.Cell, 51, 2013
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4BWX
| Structure of Neurospora crassa PAN3 pseudokinase mutant | Descriptor: | MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN-3, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Christie, M, Boland, A, Huntzinger, E, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2013-07-04 | Release date: | 2013-08-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins Mol.Cell, 51, 2013
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4BWP
| Structure of Drosophila Melanogaster PAN3 pseudokinase | Descriptor: | AMP PHOSPHORAMIDATE, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN-3 | Authors: | Christie, M, Boland, A, Huntzinger, E, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2013-07-03 | Release date: | 2013-08-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins Mol.Cell, 51, 2013
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4CZV
| Structure of the Neurospora crassa Pan2 WD40 domain | Descriptor: | CHLORIDE ION, GLYCEROL, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2 | Authors: | Peter, D, Jonas, S, Izaurralde, E, Weichenrieder, O. | Deposit date: | 2014-04-22 | Release date: | 2014-06-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay. Nat.Struct.Mol.Biol., 21, 2014
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4D0K
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4CZW
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4CZY
| Complex of Neurospora crassa PAN2 (WD40-CS1) with PAN3 (pseudokinase and C-term) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, ... | Authors: | Jonas, S, Izaurralde, E, Weichenrieder, O. | Deposit date: | 2014-04-22 | Release date: | 2014-06-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay. Nat.Struct.Mol.Biol., 21, 2014
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4CZX
| Complex of Neurospora crassa PAN2 (WD40) with PAN3 (C-TERM) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, ... | Authors: | Jonas, S, Izaurralde, E, Weichenrieder, O. | Deposit date: | 2014-04-22 | Release date: | 2014-06-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay. Nat.Struct.Mol.Biol., 21, 2014
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2WBR
| The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing | Descriptor: | GW182 | Authors: | Eulalio, A, Tritschler, F, Buettner, R, Weichenrieder, O, Izaurralde, E, Truffault, V. | Deposit date: | 2009-03-03 | Release date: | 2009-03-24 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The Rrm Domain in Gw182 Proteins Contributes to Mirna-Mediated Gene Silencing. Nucleic Acids Res., 37, 2009
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4C0G
| Structure of the NOT-box domain of human CNOT3 | Descriptor: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3 | Authors: | Boland, A, Chen, Y, Raisch, T, Jonas, S, Izaurralde, E, Weichenrieder, O. | Deposit date: | 2013-08-01 | Release date: | 2013-10-09 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and Assembly of the not Module of the Human Ccr4-not Complex Nat.Struct.Mol.Biol., 20, 2013
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4C0E
| Structure of the NOT1 superfamily homology domain from Chaetomium thermophilum | Descriptor: | NOT1 | Authors: | Chen, Y, Boland, A, Raisch, T, Jonas, S, Izaurralde, E, Weichenrieder, O. | Deposit date: | 2013-08-01 | Release date: | 2013-10-09 | Last modified: | 2013-11-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure and Assembly of the not Module of the Human Ccr4-not Complex Nat.Struct.Mol.Biol., 20, 2013
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4C0F
| Structure of the NOT-box domain of human CNOT2 | Descriptor: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2 | Authors: | Boland, A, Chen, Y, Raisch, T, Jonas, S, Izaurralde, E, Weichenrieder, O. | Deposit date: | 2013-08-01 | Release date: | 2013-10-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and Assembly of the not Module of the Human Ccr4-not Complex Nat.Struct.Mol.Biol., 20, 2013
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