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7DW0
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BU of 7dw0 by Molmil
SARS-CoV-2 Mpro mutant (H41A) in complex with nsp14|15 peptidyl substrate
Descriptor: 3C-like proteinase, nsp14/15 peptidyl substrate
Authors:Liu, X, Zhao, Y, Yang, H, Rao, Z.
Deposit date:2021-01-15
Release date:2022-01-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 119, 2022
7DW6
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BU of 7dw6 by Molmil
SARS-CoV-2 Mpro mutant (H41A) in complex with nsp15|16 peptidyl substrate
Descriptor: 3C-like proteinase, nsp15/16 peptidyl substrate
Authors:Liu, X, Zhao, Y, Yang, H, Rao, Z.
Deposit date:2021-01-15
Release date:2022-01-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 119, 2022
7DVY
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BU of 7dvy by Molmil
SARS-CoV-2 Mpro mutant (H41A) in complex with nsp9|10 peptidyl substrate
Descriptor: 3C-like proteinase, nsp9/10 peptidyl substrate
Authors:Liu, X, Zhao, Y, Yang, H, Rao, Z.
Deposit date:2021-01-15
Release date:2022-01-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 119, 2022
7DVX
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BU of 7dvx by Molmil
SARS-CoV-2 Mpro mutant (H41A) in complex with nsp6|7 peptidyl substrate
Descriptor: 3C-like proteinase, nsp6/7 peptidyl substrate
Authors:Liu, X, Zhao, Y, Yang, H, Rao, Z.
Deposit date:2021-01-15
Release date:2022-01-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 119, 2022
7DVW
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BU of 7dvw by Molmil
SARS-CoV-2 Mpro mutant (H41A) in complex with nsp5|6 peptidyl substrate
Descriptor: 3C-like proteinase, DIMETHYL SULFOXIDE, nsp5/6 peptidyl substrate
Authors:Liu, X, Zhao, Y, Yang, H, Rao, Z.
Deposit date:2021-01-15
Release date:2022-01-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 119, 2022
7E5X
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BU of 7e5x by Molmil
THE CRYSTAL STRUCTURE OF COVID-19 MAIN PROTEASE apo form at 2.2 angstrom
Descriptor: 3C-like proteinase
Authors:Liu, X, Zhao, Y, Yang, H, Rao, Z.
Deposit date:2021-02-21
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UO0
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BU of 7uo0 by Molmil
E.coli RNaseP Holoenzyme with Mg2+
Descriptor: CALCIUM ION, Precursor tRNA substrate G(-1) G(-2), RNase P RNA, ...
Authors:Huang, W, Taylor, D.J.
Deposit date:2022-04-12
Release date:2022-09-28
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
7UO1
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BU of 7uo1 by Molmil
E.coli RNaseP Holoenzyme with Mg2+
Descriptor: CALCIUM ION, E.coli RNase P RNA, Precursor tRNA substrate U(-1) and A(-2), ...
Authors:Huang, W, Taylor, D.J.
Deposit date:2022-04-12
Release date:2022-09-28
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
7UO2
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BU of 7uo2 by Molmil
E.coli RNaseP Holoenzyme with Mg2+
Descriptor: MAGNESIUM ION, RNase P RNA, Ribonuclease P protein component
Authors:Huang, W, Taylor, D.J.
Deposit date:2022-04-12
Release date:2022-09-28
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
7UO5
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BU of 7uo5 by Molmil
E.coli RNaseP Holoenzyme with Mg2+
Descriptor: CALCIUM ION, RNase P RNA, Ribonuclease P protein component
Authors:Huang, W, Taylor, D.J.
Deposit date:2022-04-12
Release date:2022-09-28
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
4J3K
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BU of 4j3k by Molmil
Structure of the N-terminal domian of human coronavirus OC43 nucleocapsid protein
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Nucleoprotein
Authors:Chen, I.J, Lin, S.Y, Hou, M.H.
Deposit date:2013-02-05
Release date:2013-05-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure-based exploration of the important role of Arg106 in the RNA-binding domain of human coronavirus OC43 nucleocapsid protein
Biochim.Biophys.Acta, 1834, 2013
4KXJ
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BU of 4kxj by Molmil
Crystal structure of HCoV-OC43 N-NTD complexed with PJ34
Descriptor: Nucleoprotein, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
Authors:Lin, S.Y, Hou, M.H.
Deposit date:2013-05-27
Release date:2014-05-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target
J.Med.Chem., 57, 2014
4LI4
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BU of 4li4 by Molmil
Crystal structure of HCoV-OC43 N-NTD complexed with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Nucleoprotein
Authors:Lin, S.Y, Liu, C.L, Hou, M.H.
Deposit date:2013-07-02
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target
J.Med.Chem., 57, 2014
4LM9
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BU of 4lm9 by Molmil
Crystal structure of HCoV-OC43 N-NTD complexed with GMP
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, Nucleoprotein
Authors:Lin, S.Y, Liu, C.L, Hou, M.H.
Deposit date:2013-07-10
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target
J.Med.Chem., 57, 2014
4LMC
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BU of 4lmc by Molmil
Crystal structure of HCoV-OC43 N-NTD complexed with CMP
Descriptor: CYTIDINE-5'-MONOPHOSPHATE, Nucleoprotein
Authors:Lin, S.Y, Liu, C.L, Hou, M.H.
Deposit date:2013-07-10
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.742 Å)
Cite:Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target
J.Med.Chem., 57, 2014
4LM7
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BU of 4lm7 by Molmil
Crystal structure of HCoV-OC43 N-NTD complexed with UMP
Descriptor: Nucleoprotein, URIDINE-5'-MONOPHOSPHATE
Authors:Lin, S.Y, Liu, C.L, Hou, M.H.
Deposit date:2013-07-10
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target
J.Med.Chem., 57, 2014
7WOS
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BU of 7wos by Molmil
The state 3 of Omicron Spike with bispecific antibody FD01
Descriptor: 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ...
Authors:Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L.
Deposit date:2022-01-22
Release date:2022-11-30
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
7WOQ
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BU of 7woq by Molmil
The state 1 of Omicron Spike with bispecific antibody FD01
Descriptor: 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L.
Deposit date:2022-01-22
Release date:2022-11-30
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
7WOU
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BU of 7wou by Molmil
The state 4 of Omicron Spike with bispecific antibody FD01
Descriptor: 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ...
Authors:Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L.
Deposit date:2022-01-22
Release date:2022-11-30
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
7WOP
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BU of 7wop by Molmil
The local refined map of Omicron spike with bispecific antibody FD01
Descriptor: 16L9, GW01, Spike protein S1
Authors:Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L.
Deposit date:2022-01-22
Release date:2022-11-30
Method:ELECTRON MICROSCOPY (3.51 Å)
Cite:Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
7WOR
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BU of 7wor by Molmil
The state 2 of Omicron Spike with bispecific antibody FD01
Descriptor: 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ...
Authors:Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L.
Deposit date:2022-01-22
Release date:2022-11-30
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
7WOV
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BU of 7wov by Molmil
The state 5 of Omicron Spike with bispecific antibody FD01
Descriptor: 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ...
Authors:Zhang, X, Zhan, W.Q, Sun, L, Chen, Z.G.
Deposit date:2022-01-22
Release date:2022-11-30
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
7WOW
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BU of 7wow by Molmil
The state 6 of Omicron Spike with bispecific antibody FD01
Descriptor: 16L9 Fv, GW01 Fv, Spike glycoprotein
Authors:Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L.
Deposit date:2022-01-22
Release date:2022-11-30
Method:ELECTRON MICROSCOPY (6.11 Å)
Cite:Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
7EMN
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BU of 7emn by Molmil
The atomic structure of SHP2 E76A mutant
Descriptor: Tyrosine-protein phosphatase non-receptor type 11
Authors:Luo, F, Xie, J.J, Zhu, J.D, Liu, C.
Deposit date:2021-04-14
Release date:2021-05-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:A novel partially open state of SHP2 points to a "multiple gear" regulation mechanism.
J.Biol.Chem., 296, 2021
7CL0
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BU of 7cl0 by Molmil
Crystal structure of human SIRT6
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NAD-dependent protein deacetylase sirtuin-6, ...
Authors:Song, K, Zhang, J.
Deposit date:2020-07-20
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Reply to: Binding site for MDL-801 on SIRT6.
Nat.Chem.Biol., 17, 2021

221716

数据于2024-06-26公开中

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