8K84
 
 | | De novo design protein -N3 | | Descriptor: | DI(HYDROXYETHYL)ETHER, De novo design protein | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-07-28 | | Release date: | 2024-07-31 | | Last modified: | 2025-05-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | De novo protein design with a denoising diffusion network independent of pretrained structure prediction models.
Nat.Methods, 21, 2024
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8KAC
 | | De novo design protein -NX1 | | Descriptor: | De novo design protein -NX1 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-02 | | Release date: | 2024-08-07 | | Last modified: | 2025-05-07 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | De novo protein design with a denoising diffusion network independent of pretrained structure prediction models.
Nat.Methods, 21, 2024
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8K8G
 | | De novo design protein -N9 | | Descriptor: | De novo design protein | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-07-29 | | Release date: | 2024-08-07 | | Last modified: | 2025-05-07 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | De novo protein design with a denoising diffusion network independent of pretrained structure prediction models.
Nat.Methods, 21, 2024
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8KC4
 | | De novo design protein -NA05 | | Descriptor: | De novo design protein -NA05 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-06 | | Release date: | 2024-08-07 | | Last modified: | 2025-05-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | De novo protein design with a denoising diffusion network independent of pretrained structure prediction models.
Nat.Methods, 21, 2024
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8KDQ
 | | De novo design protein -T03 | | Descriptor: | De novo design protein -T03 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-09 | | Release date: | 2024-08-14 | | Last modified: | 2025-05-07 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | De novo protein design with a denoising diffusion network independent of pretrained structure prediction models.
Nat.Methods, 21, 2024
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8KC1
 | | De novo design protein -NX5 | | Descriptor: | De novo design protein -NX5 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-05 | | Release date: | 2024-08-07 | | Last modified: | 2025-05-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | De novo protein design with a denoising diffusion network independent of pretrained structure prediction models.
Nat.Methods, 21, 2024
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8KC8
 | | De novo design protein -T11 | | Descriptor: | De novo design protein -T11 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-06 | | Release date: | 2024-08-07 | | Last modified: | 2025-05-07 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | De novo protein design with a denoising diffusion network independent of pretrained structure prediction models.
Nat.Methods, 21, 2024
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8KCJ
 | | De novo design protein -N7 | | Descriptor: | De novo design protein -N7, GLYCEROL | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-07 | | Release date: | 2024-08-14 | | Last modified: | 2025-05-07 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | De novo protein design with a denoising diffusion network independent of pretrained structure prediction models.
Nat.Methods, 21, 2024
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8KA7
 | | De novo design protein -NB7 | | Descriptor: | De novo design protein -NB7 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-02 | | Release date: | 2024-08-07 | | Last modified: | 2025-05-07 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | De novo protein design with a denoising diffusion network independent of pretrained structure prediction models.
Nat.Methods, 21, 2024
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5DF6
 | | Crystal structure of PTPN11 tandem SH2 domains in complex with a TXNIP peptide | | Descriptor: | Tyrosine-protein phosphatase non-receptor type 11, UNKNOWN ATOM OR ION, txnip | | Authors: | Dong, A, Li, W, Tempel, W, Liu, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2015-08-26 | | Release date: | 2015-09-23 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP.
Biochem.J., 473, 2016
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8KC5
 | | De novo design protein -T09 | | Descriptor: | De novo design protein -T09 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-06 | | Release date: | 2024-08-07 | | Last modified: | 2025-05-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | De novo protein design with a denoising diffusion network independent of pretrained structure prediction models.
Nat.Methods, 21, 2024
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8KA6
 | | De novo design protein -NA7 | | Descriptor: | De novo design protein -NA7 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-02 | | Release date: | 2024-08-07 | | Last modified: | 2025-05-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | De novo protein design with a denoising diffusion network independent of pretrained structure prediction models.
Nat.Methods, 21, 2024
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8KCK
 | | De novo design protein -N9 | | Descriptor: | De novo design protein -N9 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-07 | | Release date: | 2024-08-14 | | Last modified: | 2025-05-07 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | De novo protein design with a denoising diffusion network independent of pretrained structure prediction models.
Nat.Methods, 21, 2024
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8KC0
 | | De novo design protein -NB8 | | Descriptor: | De novo design protein -NB8 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-05 | | Release date: | 2024-08-07 | | Last modified: | 2025-05-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | De novo protein design with a denoising diffusion network independent of pretrained structure prediction models.
Nat.Methods, 21, 2024
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4PEK
 | | Crystal structure of a computationally designed retro-aldolase, RA114.3 | | Descriptor: | Retro-aldolase | | Authors: | Bhabha, G, Zhang, X, Liu, Y, Ekiert, D.C. | | Deposit date: | 2014-04-23 | | Release date: | 2015-04-08 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.
J.Am.Chem.Soc., 136, 2014
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4PEJ
 | | Crystal structure of a computationally designed retro-aldolase, RA110.4 (Cys free) | | Descriptor: | Retro-aldolase | | Authors: | Bhabha, G, Zhang, X, Liu, Y, Ekiert, D.C. | | Deposit date: | 2014-04-23 | | Release date: | 2015-04-08 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.
J.Am.Chem.Soc., 136, 2014
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4RZI
 | | Crystal structure of PhaB from Synechocystis sp. PCC 6803 | | Descriptor: | 3-ketoacyl-acyl carrier protein reductase | | Authors: | Xue, S, Liu, Y. | | Deposit date: | 2014-12-22 | | Release date: | 2015-09-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.891 Å) | | Cite: | Structure-directed construction of a high-performance version of the enzyme FabG from the photosynthetic microorganism Synechocystis sp. PCC 6803.
Febs Lett., 589, 2015
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5W3O
 | | CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:3, empty particle) | | Descriptor: | C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ... | | Authors: | Liu, Y, Dong, Y, Rossmann, M.G. | | Deposit date: | 2017-06-08 | | Release date: | 2017-07-12 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Antibody-induced uncoating of human rhinovirus B14.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5W3M
 | | CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:1, full particle) | | Descriptor: | C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ... | | Authors: | Liu, Y, Dong, Y, Rossmann, M.G. | | Deposit date: | 2017-06-08 | | Release date: | 2017-07-12 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.26 Å) | | Cite: | Antibody-induced uncoating of human rhinovirus B14.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6CV4
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6CV2
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6CV3
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6CV1
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6CVB
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6C9I
 | | Single-Particle reconstruction of DARP14 - A designed protein scaffold displaying ~17kDa DARPin proteins - Scaffold | | Descriptor: | DARP14 - Subunit A with DARPin, DARP14 - Subunit B | | Authors: | Gonen, S, Liu, Y, Yeates, T.O, Gonen, T. | | Deposit date: | 2018-01-26 | | Release date: | 2018-03-21 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Near-atomic cryo-EM imaging of a small protein displayed on a designed scaffolding system.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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