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6VHJ
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BU of 6vhj by Molmil
Solution NMR of Prochlorosin 1.1 produced by Prochlorococcus MIT 9313
Descriptor: Prochlorosin 1.1
Authors:Bobeica, S.C, van der Donk, W.A, Tang, W.
Deposit date:2020-01-09
Release date:2020-07-08
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
6VLJ
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BU of 6vlj by Molmil
Solution NMR of Prochlorosin 2.8 produced by Prochlorococcus MIT 9313
Descriptor: Prochlorosin 2.8
Authors:Bobeica, S.C, Acedo, J.Z, van der Donk, W.A, Zhu, L.
Deposit date:2020-01-24
Release date:2020-07-08
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
6VJQ
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BU of 6vjq by Molmil
Solution NMR structure of Prochlorosin 2.1 produced by Prochlorococcus MIT 9313
Descriptor: Prochlorosin 2.1
Authors:Bobeica, S.C, van der Donk, W.A, Zhu, L.
Deposit date:2020-01-16
Release date:2020-07-08
Last modified:2024-11-20
Method:SOLUTION NMR
Cite:Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
6VGT
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BU of 6vgt by Molmil
Solution NMR structure of enterococcal cytolysin L (CylLL") produced by Enterococcus faecalis
Descriptor: cytolysin L
Authors:Bobeica, S.C, van der Donk, W.A, Zhu, L, Tang, W.
Deposit date:2020-01-08
Release date:2020-07-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
6VE9
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BU of 6ve9 by Molmil
Solution NMR structure of enterococcal cytolysin S (CylLS") produced by Enterococcus faecalis
Descriptor: enterococcal cytolysin S
Authors:Bobeica, S.C, van der Donk, W.A, Zhu, L, Tang, W.
Deposit date:2019-12-30
Release date:2020-07-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
7JVF
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BU of 7jvf by Molmil
Solution NMR structure of Prochlorosin 2.10 produced by Prochlorococcus MIT 9313
Descriptor: Prochlorosin 2.10
Authors:Bobeica, S.C, van der Donk, W.A, Zhu, L.
Deposit date:2020-08-21
Release date:2020-09-09
Last modified:2024-07-10
Method:SOLUTION NMR
Cite:Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
6PO6
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BU of 6po6 by Molmil
MicroED Structure of a Natural Product VFAThiaGlu
Descriptor: YFAThiaGlu
Authors:Halaby, S, Gonen, T, Ting, C.P, Funk, M.A, van der Donk, W.A.
Deposit date:2019-07-03
Release date:2019-08-07
Last modified:2023-11-15
Method:ELECTRON CRYSTALLOGRAPHY (1 Å)
Cite:Use of a scaffold peptide in the biosynthesis of amino acid-derived natural products.
Science, 365, 2019
6PQG
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BU of 6pqg by Molmil
Solution structure of OlvA(BC)
Descriptor: OlvA(BC)
Authors:Acedo, J.Z, van der Donk, W.A.
Deposit date:2019-07-09
Release date:2019-10-23
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:O-Methyltransferase-Mediated Incorporation of a beta-Amino Acid in Lanthipeptides.
J.Am.Chem.Soc., 141, 2019
6PQF
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BU of 6pqf by Molmil
Solution structure of OlvA(BCS)
Descriptor: OlvA(BCS)
Authors:Acedo, J.Z, van der Donk, W.A.
Deposit date:2019-07-09
Release date:2019-10-23
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:O-Methyltransferase-Mediated Incorporation of a beta-Amino Acid in Lanthipeptides.
J.Am.Chem.Soc., 141, 2019
7JU9
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BU of 7ju9 by Molmil
Solution NMR structure of Prochlorosin 2.11 (Pcn2.11) produced by Prochlorococcus MIT 9313
Descriptor: Prochlorosin 2.11
Authors:Bobeica, S.C, van der Donk, W.A, Zhu, L.
Deposit date:2020-08-19
Release date:2020-09-09
Last modified:2024-07-10
Method:SOLUTION NMR
Cite:Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
2MIJ
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BU of 2mij by Molmil
NMR structure of the S-linked glycopeptide sublancin 168
Descriptor: SPBc2 prophage-derived bacteriocin sublancin-168, beta-D-glucopyranose
Authors:Garcia De Gonzalo, C.V, Zhu, L, Oman, T.J, van der Donk, W.A.
Deposit date:2013-12-13
Release date:2014-03-12
Last modified:2024-11-20
Method:SOLUTION NMR
Cite:NMR structure of the s-linked glycopeptide sublancin 168.
Acs Chem.Biol., 9, 2014
5WA3
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BU of 5wa3 by Molmil
Pyridine synthase, TbtD, from thiomuracin biosynthesis
Descriptor: Pyridine synthase TbtD
Authors:Cogan, D.P, Nair, S.K.
Deposit date:2017-06-24
Release date:2017-11-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into enzymatic [4+2] aza-cycloaddition in thiopeptide antibiotic biosynthesis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4WD9
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BU of 4wd9 by Molmil
Crystal structure of tRNA-dependent lantibiotic dehydratase NisB in complex with NisA leader peptide
Descriptor: Nisin biosynthesis protein NisB
Authors:Hao, Y, Nair, S.K.
Deposit date:2014-09-08
Release date:2014-10-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB.
Nature, 517, 2015
4E5P
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BU of 4e5p by Molmil
Thermostable phosphite dehydrogenase A176R variant in complex with NAD
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Thermostable phosphite dehydrogenase A176R variant
Authors:Zou, Y, Zhang, H, Nair, S.K.
Deposit date:2012-03-14
Release date:2012-05-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of phosphite dehydrogenase provide insights into nicotinamide cofactor regeneration.
Biochemistry, 51, 2012
2G0D
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BU of 2g0d by Molmil
Nisin cyclase
Descriptor: Nisin biosynthesis protein nisC, ZINC ION
Authors:Nair, S.K.
Deposit date:2006-02-12
Release date:2006-05-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis
Science, 311, 2006
3SZY
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BU of 3szy by Molmil
Crystal Structure of Phosphonoacetate hydrolase from Sinorhizobium meliloti 1021 in APO form
Descriptor: ZINC ION, phosphonoacetate hydrolase
Authors:Agarwal, V, Nair, S.K.
Deposit date:2011-07-19
Release date:2011-08-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural and mechanistic insights into C-p bond hydrolysis by phosphonoacetate hydrolase.
Chem.Biol., 18, 2011
3T01
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BU of 3t01 by Molmil
Crystal Structure of Phosphonoacetate hydrolase from Sinorhizobium meliloti 1021 in complex with Phosphonoformate
Descriptor: PHOSPHONOFORMIC ACID, ZINC ION, phosphonoacetate hydrolase
Authors:Agarwal, V, Nair, S.K.
Deposit date:2011-07-19
Release date:2011-08-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and mechanistic insights into C-p bond hydrolysis by phosphonoacetate hydrolase.
Chem.Biol., 18, 2011
3SZZ
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BU of 3szz by Molmil
Crystal Structure of Phosphonoacetate hydrolase from Sinorhizobium meliloti 1021 in complex with Acetate
Descriptor: ACETATE ION, ZINC ION, phosphonoacetate hydrolase
Authors:Agarwal, V, Nair, S.K.
Deposit date:2011-07-19
Release date:2011-08-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and mechanistic insights into C-p bond hydrolysis by phosphonoacetate hydrolase.
Chem.Biol., 18, 2011
3T00
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BU of 3t00 by Molmil
Crystal Structure of Phosphonoacetate hydrolase from Sinorhizobium meliloti 1021 in complex with vanadate
Descriptor: NICKEL (II) ION, VANADATE ION, ZINC ION, ...
Authors:Agarwal, V, Nair, S.K.
Deposit date:2011-07-19
Release date:2011-08-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and mechanistic insights into C-p bond hydrolysis by phosphonoacetate hydrolase.
Chem.Biol., 18, 2011
4ZOQ
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BU of 4zoq by Molmil
Crystal Structure of a Lanthipeptide Protease
Descriptor: Intracellular serine protease
Authors:Dong, S.H, Nair, S.K.
Deposit date:2015-05-06
Release date:2016-03-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Applications of the class II lanthipeptide protease LicP for sequence-specific, traceless peptide bond cleavage.
Chem Sci, 6, 2015
4YAR
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BU of 4yar by Molmil
2-Hydroxyethylphosphonate dioxygenase (HEPD) E176H
Descriptor: 2-hydroxyethylphosphonate dioxygenase, ACETATE ION, CADMIUM ION, ...
Authors:Chekan, J.R, Nair, S.K.
Deposit date:2015-02-17
Release date:2015-03-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A Common Late-Stage Intermediate in Catalysis by 2-Hydroxyethyl-phosphonate Dioxygenase and Methylphosphonate Synthase.
J.Am.Chem.Soc., 137, 2015
4QED
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BU of 4qed by Molmil
ElxO Y152F with NADPH Bound
Descriptor: ElxO, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION
Authors:Garg, N, Nair, S.K.
Deposit date:2014-05-15
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Substrate Specificity of the Lanthipeptide Peptidase ElxP and the Oxidoreductase ElxO.
Acs Chem.Biol., 9, 2014
8CZK
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BU of 8czk by Molmil
Human LanCL1 bound to GSH and Dhb-Erk peptide
Descriptor: Deb-Erk peptide, GLUTATHIONE, Glutathione S-transferase LANCL1, ...
Authors:Ongpipattanakul, C, Nair, S.K.
Deposit date:2022-05-24
Release date:2023-01-25
Last modified:2024-12-25
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:The mechanism of thia-Michael addition catalyzed by LanC enzymes.
Proc.Natl.Acad.Sci.USA, 120, 2023
8D19
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BU of 8d19 by Molmil
Human LanCL1 bound to GSH
Descriptor: GLUTATHIONE, Glutathione S-transferase LANCL1, ZINC ION
Authors:Ongpipattanakul, C, Nair, S.K.
Deposit date:2022-05-26
Release date:2023-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:The mechanism of thia-Michael addition catalyzed by LanC enzymes.
Proc.Natl.Acad.Sci.USA, 120, 2023
8CZL
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BU of 8czl by Molmil
Human LanCL1 bound to methyl glutathione (MeGSH)
Descriptor: Glutathione S-transferase LANCL1, L-GAMMA-GLUTAMYL-S-METHYLCYSTEINYLGLYCINE, ZINC ION
Authors:Ongpipattanakul, C, Nair, S.K.
Deposit date:2022-05-24
Release date:2023-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:The mechanism of thia-Michael addition catalyzed by LanC enzymes.
Proc.Natl.Acad.Sci.USA, 120, 2023

 

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