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8FHW
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BU of 8fhw by Molmil
Cryo-EM structure of Cryptococcus neoformans trehalose-6-phosphate synthase homotetramer in complex with uridine diphosphate and glucose-6-phosphate
Descriptor: 6-O-phosphono-alpha-D-glucopyranose, Alpha,alpha-trehalose-phosphate synthase (UDP-forming), URIDINE-5'-DIPHOSPHATE
Authors:Washington, E.J, Brennan, R.G.
Deposit date:2022-12-15
Release date:2023-12-20
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans : a target for novel antifungals.
Biorxiv, 2024
8FO1
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BU of 8fo1 by Molmil
Cryo-EM structure of Cryptococcus neoformans trehalose-6-phosphate synthase homotetramer in apo form
Descriptor: Alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Authors:Washington, E.J, Brennan, R.G.
Deposit date:2022-12-29
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of Cryptococcus neoformans trehalose-6-phosphate synthase homotetramer in apo form
To Be Published
5DXN
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BU of 5dxn by Molmil
Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 2
Descriptor: MAGNESIUM ION, trehalose-6-phosphate phosphatase
Authors:Miao, Y, Brennan, R.G.
Deposit date:2015-09-23
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DXI
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BU of 5dxi by Molmil
Structure of C. albicans Trehalose-6-phosphate phosphatase C-terminal domain
Descriptor: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, ...
Authors:Miao, Y, Brennan, R.G.
Deposit date:2015-09-23
Release date:2016-06-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DXF
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BU of 5dxf by Molmil
Structure of Candida albicans trehalose-6-phosphate phosphatase N-terminal domain
Descriptor: trehalose-6-phosphate phosphatase
Authors:Miao, Y, Brennan, R.G.
Deposit date:2015-09-23
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.563 Å)
Cite:Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DXL
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BU of 5dxl by Molmil
Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 1
Descriptor: trehalose-6-phosphate phosphatase
Authors:Miao, Y, Brennan, R.G.
Deposit date:2015-09-23
Release date:2016-06-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.573 Å)
Cite:Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DX9
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BU of 5dx9 by Molmil
Structure of trehalose-6-phosphate phosphatase from Cryptococcus neoformans
Descriptor: 6-O-phosphono-alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ...
Authors:Miao, Y, Brennan, R.G.
Deposit date:2015-09-23
Release date:2016-06-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DXO
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BU of 5dxo by Molmil
Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 3
Descriptor: MAGNESIUM ION, trehalose-6-phosphate phosphatase
Authors:Miao, Y, Brennan, R.G.
Deposit date:2015-09-23
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016

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