4FX7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4fx7 by Molmil](/molmil-images/mine/4fx7) | |
6YMU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ymu by Molmil](/molmil-images/mine/6ymu) | Imidazole Glycerol Phosphate Synthase | Descriptor: | Imidazole glycerol phosphate synthase subunit HisF, Imidazole glycerol phosphate synthase subunit HisH | Authors: | Sterner, R, Rajendran, C, Andrea, K. | Deposit date: | 2020-04-09 | Release date: | 2020-07-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Significance of the Protein Interface Configuration for Allostery in Imidazole Glycerol Phosphate Synthase. Biochemistry, 59, 2020
|
|
5NDY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ndy by Molmil](/molmil-images/mine/5ndy) | |
5NEZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5nez by Molmil](/molmil-images/mine/5nez) | |
4J35
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4j35 by Molmil](/molmil-images/mine/4j35) | Molecular Engineering of Organophosphate Hydrolysis Activity from a Weak Promiscuous Lactonase Template | Descriptor: | COBALT (II) ION, Phosphotriesterase, putative | Authors: | Sterner, R, Raushel, F, Meier, M, Rajendran, C, Malisi, C, Fox, N, Schlee, S, Barondeau, D, Cker, B.H. | Deposit date: | 2013-02-05 | Release date: | 2013-07-24 | Last modified: | 2013-09-04 | Method: | X-RAY DIFFRACTION (1.783 Å) | Cite: | Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template. J.Am.Chem.Soc., 135, 2013
|
|
4J9J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4j9j by Molmil](/molmil-images/mine/4j9j) | Structure of designed HisF | Descriptor: | Imidazole glycerol phosphate synthase subunit HisF | Authors: | Sterner, R, Rajendran, C, Sperl, J. | Deposit date: | 2013-02-16 | Release date: | 2013-07-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Establishing catalytic activity on an artificial ( beta alpha )8-barrel protein designed from identical half-barrels. Febs Lett., 587, 2013
|
|
8BYW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8byw by Molmil](/molmil-images/mine/8byw) | Rut B structure | Descriptor: | Ureidoacrylate amidohydrolase RutB | Authors: | Rajendran, C, Sterner, R, Busch, M. | Deposit date: | 2022-12-14 | Release date: | 2023-01-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Structural and Functional Characterization of the Ureidoacrylate Amidohydrolase RutB from Escherichia coli . Biochemistry, 62, 2023
|
|
3ZR4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zr4 by Molmil](/molmil-images/mine/3zr4) | STRUCTURAL EVIDENCE FOR AMMONIA TUNNELING ACROSS THE (BETA-ALPHA)8 BARREL OF THE IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE BIENZYME COMPLEX | Descriptor: | GLUTAMINE, GLYCEROL, IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF, ... | Authors: | Vega, M.C, Kuper, J, Haeger, M.C, Mohrlueder, J, Marquardt, S, Sterner, R, Wilmanns, M. | Deposit date: | 2011-06-13 | Release date: | 2012-10-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Catalysis Uncoupling in a Glutamine Amidotransferase Bienzyme by Unblocking the Glutaminase Active Site. Chem.Biol., 19, 2012
|
|
4QYS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qys by Molmil](/molmil-images/mine/4qys) | TrpB2 enzymes | Descriptor: | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, PHOSPHOSERINE, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Busch, F, Rajendran, C, Loeffler, P, Merkl, R, Sterner, R. | Deposit date: | 2014-07-25 | Release date: | 2015-02-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.939 Å) | Cite: | TrpB2 enzymes are O-phospho-l-serine dependent tryptophan synthases Biochemistry, 53, 2014
|
|
4MM1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mm1 by Molmil](/molmil-images/mine/4mm1) | GGGPS from Methanothermobacter thermautotrophicus | Descriptor: | Geranylgeranylglyceryl phosphate synthase, SN-GLYCEROL-1-PHOSPHATE, TRIETHYLENE GLYCOL | Authors: | Rajendran, C, Peterhoff, D, Beer, B, Kumpula, E.P, Kapetaniou, E, Guldan, H, Wierenga, R.K, Sterner, R, Babinger, P. | Deposit date: | 2013-09-07 | Release date: | 2014-06-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8004 Å) | Cite: | A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization. Mol.Microbiol., 92, 2014
|
|
4NAF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4naf by Molmil](/molmil-images/mine/4naf) | PrcB from Geobacillus kaustophilus, apo structure | Descriptor: | Heptaprenylglyceryl phosphate synthase | Authors: | Peterhoff, D, Beer, B, Rajendran, C, Kumpula, E.P, Kapetaniou, E, Guldan, H, Wierenga, R.K, Sterner, R, Babinger, P. | Deposit date: | 2013-10-22 | Release date: | 2014-06-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization. Mol.Microbiol., 92, 2014
|
|
1DL3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dl3 by Molmil](/molmil-images/mine/1dl3) | CRYSTAL STRUCTURE OF MUTUALLY GENERATED MONOMERS OF DIMERIC PHOSPHORIBOSYLANTRANILATE ISOMERASE FROM THERMOTOGA MARITIMA | Descriptor: | PROTEIN (PHOSPHORIBOSYLANTRANILATE ISOMERASE), SULFATE ION | Authors: | Thoma, R, Hennig, M, Sterner, R, Kirschner, K. | Deposit date: | 1999-12-08 | Release date: | 1999-12-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure and function of mutationally generated monomers of dimeric phosphoribosylanthranilate isomerase from Thermotoga maritima. Structure Fold.Des., 8, 2000
|
|
4NAE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nae by Molmil](/molmil-images/mine/4nae) | PcrB from Geobacillus kaustophilus, with bound G1P | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Heptaprenylglyceryl phosphate synthase, SN-GLYCEROL-1-PHOSPHATE | Authors: | Peterhoff, D, Beer, B, Rajendran, C, Kumpula, E.P, Kapetaniou, E, Guldan, H, Wierenga, R.K, Sterner, R, Babinger, P. | Deposit date: | 2013-10-22 | Release date: | 2014-06-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization. Mol.Microbiol., 92, 2014
|
|
1QO2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qo2 by Molmil](/molmil-images/mine/1qo2) | Crystal structure of N-((5'-phosphoribosyl)-formimino)-5-aminoimidazol-4-carboxamid ribonucleotid isomerase (EC 3.1.3.15, HisA) | Descriptor: | | Authors: | Wilmanns, M, Lang, D, Thoma, R, Sterner, R. | Deposit date: | 1999-11-01 | Release date: | 2000-07-12 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural Evidence for Evolution of the Beta/Alpha-Barrel Scaffold by Repeated Gene Duplication and Fusion Science, 289, 2000
|
|
2GVQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gvq by Molmil](/molmil-images/mine/2gvq) | Anthranilate phosphoribosyl-transferase (TRPD) from S. solfataricus in complex with anthranilate | Descriptor: | 2-AMINOBENZOIC ACID, Anthranilate phosphoribosyltransferase | Authors: | Marino, M, Deuss, M, Sterner, R, Mayans, O. | Deposit date: | 2006-05-03 | Release date: | 2006-05-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structural and mutational analysis of substrate complexation by anthranilate phosphoribosyltransferase from Sulfolobus solfataricus. J.Biol.Chem., 281, 2006
|
|
2W79
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2w79 by Molmil](/molmil-images/mine/2w79) | Establishing wild-type levels of catalytic activity on natural and artificial (ba)8-barrel protein scaffolds | Descriptor: | 1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE, CHLORIDE ION | Authors: | Claren, J, Malisi, C, Hocker, B, Sterner, R. | Deposit date: | 2008-12-21 | Release date: | 2009-02-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Establishing Wild-Type Levels of Catalytic Activity on Natural and Artificial (Beta Alpha)8- Barrel Protein Scaffolds. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
7A20
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7a20 by Molmil](/molmil-images/mine/7a20) | Azobenzene-Based Inhibitors for Tryptophan Synthase | Descriptor: | SODIUM ION, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM, Tryptophan synthase alpha chain,Tryptophan synthase beta chain | Authors: | Rajendran, C, Sterner, R. | Deposit date: | 2020-08-14 | Release date: | 2020-11-04 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Towards Photochromic Azobenzene-Based Inhibitors for Tryptophan Synthase. Chemistry, 27, 2021
|
|
1LBM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lbm by Molmil](/molmil-images/mine/1lbm) | |
3OG3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3og3 by Molmil](/molmil-images/mine/3og3) | Crystal structure of an artificial thermostable (BA)8-barrel protein from identical half barrels | Descriptor: | CHLORIDE ION, Imidazole glycerol phosphate synthase subunit hisF, SULFATE ION | Authors: | Sperl, J.M, Bocola, M, List, F, Kellerer, B, Sterner, R. | Deposit date: | 2010-08-16 | Release date: | 2011-08-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Design of an artificial thermostable (BA)8-barrel protein from identical half barrels To be Published
|
|
6RTZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rtz by Molmil](/molmil-images/mine/6rtz) | |
6RU0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ru0 by Molmil](/molmil-images/mine/6ru0) | |
1VJW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1vjw by Molmil](/molmil-images/mine/1vjw) | STRUCTURE OF OXIDOREDUCTASE (NADP+(A),FERREDOXIN(A)) | Descriptor: | FERREDOXIN(A), IRON/SULFUR CLUSTER | Authors: | Macedo-Ribeiro, S, Darimont, B, Sterner, R, Huber, R. | Deposit date: | 1996-10-09 | Release date: | 1996-12-23 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Small structural changes account for the high thermostability of 1[4Fe-4S] ferredoxin from the hyperthermophilic bacterium Thermotoga maritima. Structure, 4, 1996
|
|
2W6R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2w6r by Molmil](/molmil-images/mine/2w6r) | Crystal structure of an artificial (ba)8-barrel protein designed from identical half barrels | Descriptor: | IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF | Authors: | Hocker, B, Lochner, A, Seitz, T, Claren, J, Sterner, R. | Deposit date: | 2008-12-18 | Release date: | 2009-02-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | High-Resolution Crystal Structure of an Artificial (Betaalpha)(8)-Barrel Protein Designed from Identical Half-Barrels. Biochemistry, 48, 2009
|
|
2WJZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wjz by Molmil](/molmil-images/mine/2wjz) | Crystal structure of (HisH) K181A Y138A mutant of imidazoleglycerolphosphate synthase (HisH HisF) which displays constitutive glutaminase activity | Descriptor: | IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE HISF, IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISH, PHOSPHATE ION | Authors: | Vega, M.C, List, F, Razeto, A, Haeger, M.C, Babinger, K, Kuper, J, Sterner, R, Wilmanns, M. | Deposit date: | 2009-06-02 | Release date: | 2010-08-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Catalysis Uncoupling in a Glutamine Amidotransferase Bienzyme by Unblocking the Glutaminase Active Site. Chem.Biol., 19, 2012
|
|
3MNP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mnp by Molmil](/molmil-images/mine/3mnp) | Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by (A611V, V708A, E711G) mutations at 1.50A | Descriptor: | DEXAMETHASONE, GLYCEROL, Glucocorticoid receptor, ... | Authors: | Schoch, G.A, Seitz, T, Benz, J, Banner, D, Stihle, M, D'Arcy, B, Thoma, R, Sterner, R, Hennig, M, Ruf, A. | Deposit date: | 2010-04-22 | Release date: | 2010-09-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening. J.Mol.Biol., 403, 2010
|
|