1Y2M
| Crystal structure of phenylalanine ammonia-lyase from yeast Rhododporidium toruloides | Descriptor: | Phenylalanine ammonia-lyase | Authors: | Wang, L, Gamez, A, Sarkissian, C.N, Straub, M, Patch, M.G, Han, G.W, Scriver, C.R, Stevens, R.C. | Deposit date: | 2004-11-22 | Release date: | 2005-11-01 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure-based chemical modification strategy for enzyme replacement treatment of phenylketonuria. Mol.Genet.Metab., 86, 2005
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1TG2
| Crystal structure of phenylalanine hydroxylase A313T mutant with 7,8-dihydrobiopterin bound | Descriptor: | 2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-7,8-DIHYDRO-6H-PTERIDIN-4-ONE, FE (III) ION, Phenylalanine-4-hydroxylase | Authors: | Erlandsen, H, Pey, A.L, Gamez, A, Perez, B, Desviat, L.R, Aguado, C, Koch, R, Surendran, S, Tyring, S, Matalon, R, Scriver, C.R, Ugarte, M, Martinez, A, Stevens, R.C. | Deposit date: | 2004-05-28 | Release date: | 2004-11-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations. Proc.Natl.Acad.Sci.Usa, 101, 2004
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1TDW
| Crystal structure of double truncated human phenylalanine hydroxylase BH4-responsive PKU mutant A313T. | Descriptor: | FE (III) ION, Phenylalanine-4-hydroxylase | Authors: | Erlandsen, H, Pey, A.L, Gamez, A, Perez, B, Desviat, L.R, Aguado, C, Koch, R, Surendran, S, Tyring, S, Matalon, R, Scriver, C.R, Ugarte, M, Martinez, A, Stevens, R.C. | Deposit date: | 2004-05-24 | Release date: | 2004-11-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations. Proc.Natl.Acad.Sci.Usa, 101, 2004
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3CZO
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