8QDH
 
 | | Engineered LmrR carrying a cyclic boronate ester formed between Tris and p-boronophenylalanine at position 89 | | Descriptor: | GLYCEROL, Transcriptional regulator, PadR-like family | | Authors: | Thunnissen, A.M.W.H, Rozeboom, H.J, Longwitz, L, Leveson-Gower, R.B, Roelfes, G. | | Deposit date: | 2023-08-29 | | Release date: | 2024-05-01 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Boron catalysis in a designer enzyme.
Nature, 629, 2024
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8QDF
 | | Engineered LmrR with Met-89 replaced by para-boronophenylalanine | | Descriptor: | Transcriptional regulator, PadR-like family | | Authors: | Thunnissen, A.M.W.H, Rozeboom, H.J, Longwitz, L, Leveson-Gower, R.B, Roelfes, G. | | Deposit date: | 2023-08-29 | | Release date: | 2024-05-01 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Boron catalysis in a designer enzyme.
Nature, 629, 2024
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9G51
 | | Crystal structure of LmrR with V15 replaced by unnatural amino acid 4-mercaptophenylalanine, apo | | Descriptor: | Transcriptional regulator, PadR-like family | | Authors: | Thunnissen, A.M.W.H, Aalbers, F.S, Veen, M.J, Rozeboom, H.J, Roelfes, G. | | Deposit date: | 2024-07-16 | | Release date: | 2024-12-25 | | Last modified: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Artificial Gold Enzymes Using a Genetically Encoded Thiophenol-Based Noble-Metal-Binding Ligand.
Angew.Chem.Int.Ed.Engl., 64, 2025
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9G52
 | | Crystal structure of LmrR with V15 replaced by unnatural amino acid 4-mercaptophenylalanine, Au(I) bound | | Descriptor: | GOLD ION, Transcriptional regulator, PadR-like family | | Authors: | Thunnissen, A.M.W.H, Aalbers, F.S, Veen, M.J, Rozeboom, H.J, Roelfes, G. | | Deposit date: | 2024-07-16 | | Release date: | 2024-12-25 | | Last modified: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Artificial Gold Enzymes Using a Genetically Encoded Thiophenol-Based Noble-Metal-Binding Ligand.
Angew.Chem.Int.Ed.Engl., 64, 2025
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9GTV
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9GKT
 | | Crystal structure of artificial enzyme LmrR_pAF variant RGN | | Descriptor: | Transcriptional regulator, PadR-like family | | Authors: | Thunnissen, A.M.W.H, Leveson-Gower, R.B, Rozeboom, H.J, Roelfes, G. | | Deposit date: | 2024-08-26 | | Release date: | 2025-02-26 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Evolutionary Specialization of a Promiscuous Designer Enzyme.
Acs Catalysis, 15, 2025
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9GKR
 | | Crystal structure of artificial enzyme LmrR_pAF variant RMH in crystal form 1 | | Descriptor: | Transcriptional regulator, PadR-like family | | Authors: | Thunnissen, A.M.W.H, Leveson-Gower, R.B, Rozeboom, H.J, Roelfes, G. | | Deposit date: | 2024-08-26 | | Release date: | 2025-02-26 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Evolutionary Specialization of a Promiscuous Designer Enzyme.
Acs Catalysis, 15, 2025
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9GKS
 | | Crystal structure of artificial enzyme LmrR_pAF variant RMH in crystal form 2 | | Descriptor: | Transcriptional regulator, PadR-like family | | Authors: | Thunnissen, A.M.W.H, Leveson-Gower, R.B, Rozeboom, H.J, Roelfes, G. | | Deposit date: | 2024-08-26 | | Release date: | 2025-02-26 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Evolutionary Specialization of a Promiscuous Designer Enzyme.
Acs Catalysis, 15, 2025
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9H9X
 | | Crystal structure of metal-free LmrR_V15Bpy in a closed state | | Descriptor: | Transcriptional regulator, PadR-like family | | Authors: | Thunnissen, A.M.W.H, Jiang, R, Casilli, F, Aalbers, F, Roelfes, G. | | Deposit date: | 2024-11-01 | | Release date: | 2025-03-05 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | An artificial copper-Michaelase featuring a genetically encoded bipyridine ligand for asymmetric additions to nitroalkenes.
Angew.Chem.Int.Ed.Engl., 2025
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9H9Y
 | | Crystal structure of metal-free LmrR_V15Bpy variant BVS in a closed state | | Descriptor: | Transcriptional regulator, PadR-like family | | Authors: | Thunnissen, A.M.W.H, Jiang, R, Casilli, F, Aalbers, F, Roelfes, G. | | Deposit date: | 2024-11-01 | | Release date: | 2025-03-05 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | An artificial copper-Michaelase featuring a genetically encoded bipyridine ligand for asymmetric additions to nitroalkenes.
Angew.Chem.Int.Ed.Engl., 2025
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9HA0
 | | Crystal structure of Cu(II)-bound LmrR_V15Bpy variant BVS | | Descriptor: | COPPER (II) ION, GLYCEROL, IMIDAZOLE, ... | | Authors: | Thunnissen, A.M.W.H, Jiang, R, Casilli, F, Aalbers, F, Roelfes, G. | | Deposit date: | 2024-11-01 | | Release date: | 2025-03-05 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | An artificial copper-Michaelase featuring a genetically encoded bipyridine ligand for asymmetric additions to nitroalkenes.
Angew.Chem.Int.Ed.Engl., 2025
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9H9W
 | | Crystal structure of metal-free LmrR_V15Bpy in an open state | | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Transcriptional regulator, PadR-like family | | Authors: | Thunnissen, A.M.W.H, Jiang, R, Casilli, F, Aalbers, F, Roelfes, G. | | Deposit date: | 2024-11-01 | | Release date: | 2025-03-05 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | An artificial copper-Michaelase featuring a genetically encoded bipyridine ligand for asymmetric additions to nitroalkenes.
Angew.Chem.Int.Ed.Engl., 2025
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9H9Z
 | | Crystal structure of Cu(II)-bound LmrR_V15Bpy | | Descriptor: | COPPER (II) ION, MALONATE ION, Transcriptional regulator, ... | | Authors: | Thunnissen, A.M.W.H, Jiang, R, Casilli, F, Aalbers, F, Roelfes, G. | | Deposit date: | 2024-11-01 | | Release date: | 2025-03-05 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | An artificial copper-Michaelase featuring a genetically encoded bipyridine ligand for asymmetric additions to nitroalkenes.
Angew.Chem.Int.Ed.Engl., 2025
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6I8N
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6R1L
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6FUU
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