8OGI
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![BU of 8ogi by Molmil](/molmil-images/mine/8ogi) | Structure of native human eosinophil peroxidase | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Pfanzagl, V, Obinger, C. | Deposit date: | 2023-03-20 | Release date: | 2024-01-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.547 Å) | Cite: | Posttranslational modification and heme cavity architecture of human eosinophil peroxidase-insights from first crystal structure and biochemical characterization. J.Biol.Chem., 299, 2023
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5CJH
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![BU of 5cjh by Molmil](/molmil-images/mine/5cjh) | Crystal Structure of Eukaryotic Oxoiron MagKatG2 at pH 8.5 | Descriptor: | Catalase-peroxidase 2, HYDROXIDE ION, Peroxidized Heme | Authors: | Gasselhuber, B, Obinger, C, Fita, I, Carpena, X. | Deposit date: | 2015-07-14 | Release date: | 2015-09-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Eukaryotic Catalase-Peroxidase: The Role of the Trp-Tyr-Met Adduct in Protein Stability, Substrate Accessibility, and Catalysis of Hydrogen Peroxide Dismutation. Biochemistry, 54, 2015
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3UT2
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![BU of 3ut2 by Molmil](/molmil-images/mine/3ut2) | Crystal Structure of Fungal MagKatG2 | Descriptor: | Catalase-peroxidase 2, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Zamocky, M, Garcia-Fernandez, M.Q, Gasselhuber, B, Jakopitsch, C, Furtmuller, P.G, Loewen, P.C, Fita, I, Obinger, C, Carpena, X. | Deposit date: | 2011-11-24 | Release date: | 2012-07-25 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.549 Å) | Cite: | High Conformational Stability of Secreted Eukaryotic Catalase-peroxidases: ANSWERS FROM FIRST CRYSTAL STRUCTURE AND UNFOLDING STUDIES. J.Biol.Chem., 287, 2012
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3F9P
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![BU of 3f9p by Molmil](/molmil-images/mine/3f9p) | Crystal structure of myeloperoxidase from human leukocytes | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | Authors: | Carpena, X, Fita, I, Obinger, C. | Deposit date: | 2008-11-14 | Release date: | 2009-07-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.93 Å) | Cite: | Essential role of proximal histidine-asparagine interaction in Mammalian peroxidases. J.Biol.Chem., 284, 2009
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6XUC
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![BU of 6xuc by Molmil](/molmil-images/mine/6xuc) | Structure of coproheme decarboxylase from Corynebacterium diphteriae in complex with coproheme | Descriptor: | 1,3,5,8-TETRAMETHYL-PORPHINE-2,4,6,7-TETRAPROPIONIC ACID FERROUS COMPLEX, Chlorite dismutase | Authors: | Michlits, H, Lier, B, Pfanzagl, V, Djinovic-Carugo, K, Furtmueller, P.G, Oostenbrink, C, Obinger, C, Hofbauer, S. | Deposit date: | 2020-01-17 | Release date: | 2020-04-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8702 Å) | Cite: | Actinobacterial Coproheme Decarboxylases Use Histidine as a Distal Base to Promote Compound I Formation. Acs Catalysis, 10, 2020
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6XUB
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![BU of 6xub by Molmil](/molmil-images/mine/6xub) | Structure of coproheme decarboxylase from Corynebacterium diphteriae in complex with monovinyl monopropionyl deuteroheme | Descriptor: | Chlorite dismutase, harderoheme (III) | Authors: | Michlits, H, Lier, B, Pfanzagl, V, Djinovic-Carugo, K, Furtmueller, P.G, Oostenbrink, C, Obinger, C, Hofbauer, S. | Deposit date: | 2020-01-17 | Release date: | 2020-04-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Actinobacterial Coproheme Decarboxylases Use Histidine as a Distal Base to Promote Compound I Formation. Acs Catalysis, 10, 2020
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1GV3
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![BU of 1gv3 by Molmil](/molmil-images/mine/1gv3) | The 2.0 Angstrom resolution structure of the catalytic portion of a cyanobacterial membrane-bound manganese superoxide dismutase | Descriptor: | MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE | Authors: | Atzenhofer, W, Regelsberger, G, Jacob, U, Huber, R, Peschek, G.A, Obinger, C. | Deposit date: | 2002-02-05 | Release date: | 2002-08-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The 2.0A Resolution Structure of the Catalytic Portion of a Cyanobacterial Membrane-Bound Manganese Superoxide Dismutase J.Mol.Biol., 321, 2002
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7ATI
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![BU of 7ati by Molmil](/molmil-images/mine/7ati) | Crystal structure of dimeric chlorite dismutase variant Q74V (CCld Q74V) from Cyanothece sp. PCC7425 | Descriptor: | Chlorite dismutase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Schmidt, D, Mlynek, G, Djinovic-Carugo, K, Obinger, C. | Deposit date: | 2020-10-30 | Release date: | 2021-02-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Arresting the Catalytic Arginine in Chlorite Dismutases: Impact on Heme Coordination, Thermal Stability, and Catalysis. Biochemistry, 60, 2021
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7ASB
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![BU of 7asb by Molmil](/molmil-images/mine/7asb) | Crystal structure of dimeric chlorite dismutase variant Q74E (CCld Q74E) from Cyanothece sp. PCC7425 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Chlorite dismutase, DI(HYDROXYETHYL)ETHER, ... | Authors: | Schmidt, D, Mlynek, G, Djinovic-Carugo, K, Obinger, C. | Deposit date: | 2020-10-27 | Release date: | 2021-02-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Arresting the Catalytic Arginine in Chlorite Dismutases: Impact on Heme Coordination, Thermal Stability, and Catalysis. Biochemistry, 60, 2021
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5JHX
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![BU of 5jhx by Molmil](/molmil-images/mine/5jhx) | Crystal Structure of Fungal MagKatG2 at pH 3.0 | Descriptor: | CITRATE ANION, Catalase-peroxidase 2, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Gasselhuber, B, Obinger, C, Carpena, X. | Deposit date: | 2016-04-21 | Release date: | 2016-06-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Interaction with the Redox Cofactor MYW and Functional Role of a Mobile Arginine in Eukaryotic Catalase-Peroxidase. Biochemistry, 55, 2016
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5JHY
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![BU of 5jhy by Molmil](/molmil-images/mine/5jhy) | |
5JHZ
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![BU of 5jhz by Molmil](/molmil-images/mine/5jhz) | |
3NN4
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![BU of 3nn4 by Molmil](/molmil-images/mine/3nn4) | Structure of chlorite dismutase from Candidatus Nitrospira defluvii R173K mutant | Descriptor: | Chlorite dismutase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Kostan, J, Sjoeblom, B, Maixner, F, Mlynek, G, Furtmueller, P.G, Obinger, C, Wagner, M, Daims, H, Djinovic-Carugo, K. | Deposit date: | 2010-06-23 | Release date: | 2010-07-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and functional characterisation of the chlorite dismutase from the nitrite-oxidizing bacterium "Candidatus Nitrospira defluvii": Identification of a catalytically important amino acid residue J.Struct.Biol., 172, 2010
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5JIK
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![BU of 5jik by Molmil](/molmil-images/mine/5jik) | Crystal structure of HER2 binding IgG1-Fc (Fcab H10-03-6) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Humm, A, Lobner, E, Mlynek, G, Obinger, C, Djinovic-Carugo, K. | Deposit date: | 2016-04-22 | Release date: | 2017-04-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies. Structure, 25, 2017
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5JIH
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![BU of 5jih by Molmil](/molmil-images/mine/5jih) | Crystal structure of HER2 binding IgG1-Fc (Fcab STAB19) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region | Authors: | Humm, A, Lobner, E, Mlynek, G, Obinger, C, Djinovic-Carugo, K. | Deposit date: | 2016-04-22 | Release date: | 2017-04-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.663 Å) | Cite: | Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies. Structure, 25, 2017
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5JII
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![BU of 5jii by Molmil](/molmil-images/mine/5jii) | Crystal structure of human IgG1-Fc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ig gamma-1 chain C region, ... | Authors: | Humm, A, Lobner, E, Mlynek, G, Obinger, C, Djinovic-Carugo, K. | Deposit date: | 2016-04-22 | Release date: | 2017-04-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies. Structure, 25, 2017
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3NN2
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![BU of 3nn2 by Molmil](/molmil-images/mine/3nn2) | Structure of chlorite dismutase from Candidatus Nitrospira defluvii in complex with cyanide | Descriptor: | CYANIDE ION, Chlorite dismutase, GLYCEROL, ... | Authors: | Kostan, J, Sjoeblom, B, Maixner, F, Mlynek, G, Furtmueller, P.G, Obinger, C, Wagner, M, Daims, H, Djinovic-Carugo, K. | Deposit date: | 2010-06-23 | Release date: | 2010-07-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structural and functional characterisation of the chlorite dismutase from the nitrite-oxidizing bacterium "Candidatus Nitrospira defluvii": Identification of a catalytically important amino acid residue J.Struct.Biol., 172, 2010
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3NN1
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![BU of 3nn1 by Molmil](/molmil-images/mine/3nn1) | Structure of chlorite dismutase from Candidatus Nitrospira defluvii in complex with imidazole | Descriptor: | 1,2-ETHANEDIOL, Chlorite dismutase, IMIDAZOLE, ... | Authors: | Kostan, J, Sjoeblom, B, Maixner, F, Mlynek, G, Furtmueller, P.G, Obinger, C, Wagner, M, Daims, H, Djinovic-Carugo, K. | Deposit date: | 2010-06-23 | Release date: | 2010-07-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural and functional characterisation of the chlorite dismutase from the nitrite-oxidizing bacterium "Candidatus Nitrospira defluvii": Identification of a catalytically important amino acid residue J.Struct.Biol., 172, 2010
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3NN3
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![BU of 3nn3 by Molmil](/molmil-images/mine/3nn3) | Structure of chlorite dismutase from Candidatus Nitrospira defluvii R173A mutant | Descriptor: | Chlorite dismutase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Kostan, J, Sjoeblom, B, Maixner, F, Mlynek, G, Furtmueller, P.G, Obinger, C, Wagner, M, Daims, H, Djinovic-Carugo, K. | Deposit date: | 2010-06-23 | Release date: | 2010-07-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and functional characterisation of the chlorite dismutase from the nitrite-oxidizing bacterium "Candidatus Nitrospira defluvii": Identification of a catalytically important amino acid residue J.Struct.Biol., 172, 2010
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5K33
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![BU of 5k33 by Molmil](/molmil-images/mine/5k33) | Crystal structure of extracellular domain of HER2 in complex with Fcab STAB19 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ig gamma-1 chain C region, ... | Authors: | Humm, A, Lobner, E, Goritzer, K, Mlynek, G, Obinger, C, Djinovic-Carugo, K. | Deposit date: | 2016-05-19 | Release date: | 2017-04-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies. Structure, 25, 2017
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5KWG
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![BU of 5kwg by Molmil](/molmil-images/mine/5kwg) | Crystal structure of extracellular domain of HER2 in complex with Fcab H10-03-6 | Descriptor: | Ig gamma-1 chain C region, Receptor tyrosine-protein kinase erbB-2 | Authors: | Humm, A, Lobner, E, Goritzer, K, Mlynek, G, Obinger, C, Djinovic-Carugo, K. | Deposit date: | 2016-07-18 | Release date: | 2017-04-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (4.3 Å) | Cite: | Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies. Structure, 25, 2017
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5NKV
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![BU of 5nkv by Molmil](/molmil-images/mine/5nkv) | Crystal structure of dimeric chlorite dismutase from Cyanothece sp. PCC7425 at pH 9.0 and 293 K. | Descriptor: | CHLORIDE ION, Chlorite Dismutase, GLYCEROL, ... | Authors: | Puehringer, D, Schaffner, I, Mlynek, G, Obinger, C, Djinovic-Carugo, K. | Deposit date: | 2017-04-03 | Release date: | 2018-01-31 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular Mechanism of Enzymatic Chlorite Detoxification: Insights from Structural and Kinetic Studies. ACS Catal, 7, 2017
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5MFA
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![BU of 5mfa by Molmil](/molmil-images/mine/5mfa) | Crystal structure of human promyeloperoxidase (proMPO) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Grishkovskaya, I, Furtmueller, P.G, Obinger, C, Djinovic-Carugo, K. | Deposit date: | 2016-11-17 | Release date: | 2017-04-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structure of human promyeloperoxidase (proMPO) and the role of the propeptide in processing and maturation. J. Biol. Chem., 292, 2017
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5O4E
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![BU of 5o4e by Molmil](/molmil-images/mine/5o4e) | Crystal structure of VEGF in complex with heterodimeric Fcab JanusCT6 | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | Authors: | Mlynek, G, Lobner, E, Kubinger, K, Humm, A, Obinger, C, Djinovic-Carugo, K. | Deposit date: | 2017-05-29 | Release date: | 2017-08-30 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 angstrom crystal structure of the complex. MAbs, 9, 2017
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5NKU
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![BU of 5nku by Molmil](/molmil-images/mine/5nku) | Joint neutron/X-ray structure of dimeric chlorite dismutase from Cyanothece sp. PCC7425 | Descriptor: | CHLORIDE ION, Chlorite Dismutase, GLYCEROL, ... | Authors: | Puehringer, D, Schaffner, I, Mlynek, G, Obinger, C, Djinovic-Carugo, K. | Deposit date: | 2017-04-03 | Release date: | 2018-02-28 | Last modified: | 2024-05-01 | Method: | NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION | Cite: | Molecular Mechanism of Enzymatic Chlorite Detoxification: Insights from Structural and Kinetic Studies. ACS Catal, 7, 2017
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