7NCS
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8BWC
| E. coli BAM complex (BamABCDE) wild-type | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | Authors: | Machin, J.M, Radford, S.E, Ranson, N.A. | Deposit date: | 2022-12-06 | Release date: | 2023-05-24 | Last modified: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Darobactin B Stabilises a Lateral-Closed Conformation of the BAM Complex in E. coli Cells. Angew.Chem.Int.Ed.Engl., 62, 2023
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6SSZ
| Structure of the Plasmodium falciparum falcipain 2 protease in complex with an (E)-chalcone inhibitor. | Descriptor: | (~{E})-3-(1,3-benzodioxol-5-yl)-1-(3-nitrophenyl)prop-2-en-1-one, Cysteine proteinase falcipain 2a | Authors: | Machin, J, Kantsadi, A, Vakonakis, I. | Deposit date: | 2019-09-09 | Release date: | 2019-12-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | The complex of Plasmodium falciparum falcipain-2 protease with an (E)-chalcone-based inhibitor highlights a novel, small, molecule-binding site. Malar.J., 18, 2019
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7BNQ
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7BM5
| Crystal structure of Fab1, the Fab fragment of the anti-BamA monoclonal antibody MAB1 | Descriptor: | Fab1 heavy chain, Fab1 light chain | Authors: | White, P, Storek, K.M, Rutherford, S.T, Radford, S.E. | Deposit date: | 2021-01-19 | Release date: | 2021-06-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding. Nat Commun, 12, 2021
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7NBX
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7ND0
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8QPZ
| CryoEM structure of recombinant DeltaN7 alpha-synuclein in PBS | Descriptor: | Alpha-synuclein | Authors: | Thacker, D, Wilkinson, M, Dewison, K.M, Ranson, N.A, Brockwell, D.J, Radford, S.E. | Deposit date: | 2023-10-03 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Residues 2 to 7 of alpha-synuclein regulate amyloid formation via lipid-dependent and lipid-independent pathways. Proc.Natl.Acad.Sci.USA, 121, 2024
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