5FEM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fem by Molmil](/molmil-images/mine/5fem) | |
6U9D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u9d by Molmil](/molmil-images/mine/6u9d) | |
6WO1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wo1 by Molmil](/molmil-images/mine/6wo1) | |
5WJ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wj1 by Molmil](/molmil-images/mine/5wj1) | Crystal structure of Arabidopsis thaliana acetohydroxyacid synthase in complex with a triazolopyrimidine herbicide, penoxsulam | Descriptor: | (3Z)-4-{[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]AMINO}-3-MERCAPTOPENT-3-EN-1-YL TRIHYDROGEN DIPHOSPHATE, 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide, Acetolactate synthase, ... | Authors: | Garcia, M.D, Lonhienne, T, Guddat, L.W. | Deposit date: | 2017-07-21 | Release date: | 2018-02-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.522 Å) | Cite: | Structural insights into the mechanism of inhibition of AHAS by herbicides. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6BD3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bd3 by Molmil](/molmil-images/mine/6bd3) | Saccharomyces cerevisiae acetohydroxyacid synthase | Descriptor: | 2-ACETYL-THIAMINE DIPHOSPHATE, ACETATE ION, Acetolactate synthase catalytic subunit, ... | Authors: | Guddat, L.W, Lonhienne, T. | Deposit date: | 2017-10-21 | Release date: | 2017-11-08 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | High resolution crystal structures of the acetohydroxyacid synthase-pyruvate complex provide new insights into its catalytic mechanism Chemistryselect, 2017
|
|
6BD9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bd9 by Molmil](/molmil-images/mine/6bd9) | Saccharomyces cerevisiae acetohydroxyacid synthase | Descriptor: | Acetolactate synthase catalytic subunit, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Guddat, L.W, Lonhienne, T. | Deposit date: | 2017-10-22 | Release date: | 2017-11-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.982 Å) | Cite: | High resolution crystal structures of the acetohydroxyacid synthase-pyruvate complex provide new insights into its catalytic mechanism Chemistryselect, 2017
|
|
4ZM1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zm1 by Molmil](/molmil-images/mine/4zm1) | Shigella flexneri lipopolysaccharide O-antigen chain-length regulator WzzBSF - wild type | Descriptor: | CITRIC ACID, Chain length determinant protein, MAGNESIUM ION | Authors: | Ericsson, D.J, Chang, C.-W, Lonhienne, T, Casey, L, Benning, F, Kobe, B, Tran, E.N.H, Morona, R. | Deposit date: | 2015-05-02 | Release date: | 2016-03-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural and Biochemical Analysis of a Single Amino-Acid Mutant of WzzBSF That Alters Lipopolysaccharide O-Antigen Chain Length in Shigella flexneri. Plos One, 10, 2015
|
|
4ZM5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zm5 by Molmil](/molmil-images/mine/4zm5) | Shigella flexneri lipopolysaccharide O-antigen chain-length regulator WzzBSF - A107P mutant | Descriptor: | CHLORIDE ION, Chain length determinant protein, MAGNESIUM ION | Authors: | Ericsson, D.J, Chang, C.-W, Lonhienne, T, Casey, L, Benning, F, Kobe, B, Tran, E.N.H, Morona, R. | Deposit date: | 2015-05-02 | Release date: | 2016-03-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structural and Biochemical Analysis of a Single Amino-Acid Mutant of WzzBSF That Alters Lipopolysaccharide O-Antigen Chain Length in Shigella flexneri. Plos One, 10, 2015
|
|
8SWM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8swm by Molmil](/molmil-images/mine/8swm) | |
8SXD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sxd by Molmil](/molmil-images/mine/8sxd) | |
8EPZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8epz by Molmil](/molmil-images/mine/8epz) | |
8EJ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ej0 by Molmil](/molmil-images/mine/8ej0) | |
8UPP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8upp by Molmil](/molmil-images/mine/8upp) | Campylobacter jejuni ketol-acid reductoisomerase in complex with NADPH and Hoe704 | Descriptor: | (2R)-(dimethylphosphoryl)(hydroxy)acetic acid, Ketol-acid reductoisomerase, MAGNESIUM ION, ... | Authors: | Lin, X, Lv, Y, Lonhienne, T, Guddat, L.W. | Deposit date: | 2023-10-23 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase Acs Catalysis, 2024
|
|
8UPN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8upn by Molmil](/molmil-images/mine/8upn) | |
8UPQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8upq by Molmil](/molmil-images/mine/8upq) | Campylobacter jejuni ketol-acid reductoisomerase in complex with 2,3-dihydroxy-3-isovalerate. | Descriptor: | (2R)-2,3-dihydroxy-3-methylbutanoic acid, Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION | Authors: | Lin, X, Lonhienne, T, Guddat, L.W. | Deposit date: | 2023-10-23 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase Acs Catalysis, 2024
|
|
5IMS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ims by Molmil](/molmil-images/mine/5ims) | |
5K6Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5k6q by Molmil](/molmil-images/mine/5k6q) | Crystal structure of Arabidopsis thaliana acetohydroxyacid synthase catalytic subunit | Descriptor: | 2-[(2E)-3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-HYDROXYETHYLIDENE)-4-METHYL-2,3-DIHYDRO-1,3-THIAZOL-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Acetolactate synthase, ... | Authors: | Garcia, M.D, Wang, J.-G, Lonhienne, T, Guddat, L.W. | Deposit date: | 2016-05-25 | Release date: | 2017-05-31 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.952 Å) | Cite: | Crystal structure of plant acetohydroxyacid synthase, the target for several commercial herbicides. FEBS J., 284, 2017
|
|
5WKC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wkc by Molmil](/molmil-images/mine/5wkc) | Saccharomyces cerevisiae acetohydroxyacid synthase in complex with the herbicide penoxsulam | Descriptor: | (3Z)-4-{[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]AMINO}-3-MERCAPTOPENT-3-EN-1-YL TRIHYDROGEN DIPHOSPHATE, 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide, 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-2-[(1~{S})-1-(dioxidanyl)-1-oxidanyl-ethyl]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, ... | Authors: | Guddat, W.L, Lonhienne, G.T. | Deposit date: | 2017-07-25 | Release date: | 2018-02-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.334 Å) | Cite: | Structural insights into the mechanism of inhibition of AHAS by herbicides. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6U9H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u9h by Molmil](/molmil-images/mine/6u9h) | Arabidopsis thaliana acetohydroxyacid synthase complex | Descriptor: | Acetolactate synthase small subunit 2, chloroplastic, Acetolactate synthase, ... | Authors: | Guddat, L.W, Low, Y.S, Rao, Z. | Deposit date: | 2019-09-08 | Release date: | 2020-07-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of fungal and plant acetohydroxyacid synthases. Nature, 586, 2020
|
|
6VZ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vz8 by Molmil](/molmil-images/mine/6vz8) | |
7STQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7stq by Molmil](/molmil-images/mine/7stq) | Crystal structure of arabidopsis thaliana acetohydroxyacid synthase W574L mutant in complex with chlorimuron-ethyl | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-[[[[(4-CHLORO-6-METHOXY-2-PYRIMIDINYL)AMINO]CARBONYL]AMINO]SULFONYL]BENZOIC ACID ETHYL ESTER, 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, ... | Authors: | Guddat, L.W, Cheng, Y. | Deposit date: | 2021-11-15 | Release date: | 2022-06-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis of resistance to herbicides that target acetohydroxyacid synthase. Nat Commun, 13, 2022
|
|
7U1D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7u1d by Molmil](/molmil-images/mine/7u1d) | |
7U25
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7u25 by Molmil](/molmil-images/mine/7u25) | Crystal structure of arabidopsis thaliana acetohydroxyacid synthase W574L mutant in complex with bispyribac-sodium | Descriptor: | 2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, ... | Authors: | Guddat, L.W, Cheng, Y. | Deposit date: | 2022-02-23 | Release date: | 2022-06-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Structural basis of resistance to herbicides that target acetohydroxyacid synthase. Nat Commun, 13, 2022
|
|
7U1U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7u1u by Molmil](/molmil-images/mine/7u1u) | |
7TZZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tzz by Molmil](/molmil-images/mine/7tzz) | Crystal structure of arabidopsis thaliana acetohydroxyacid synthase P197T mutant in complex with bispyribac-sodium | Descriptor: | 2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid, 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-2-[(1~{S})-1-(dioxidanyl)-1-oxidanyl-ethyl]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... | Authors: | Guddat, L.W, Cheng, Y. | Deposit date: | 2022-02-16 | Release date: | 2022-06-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structural basis of resistance to herbicides that target acetohydroxyacid synthase. Nat Commun, 13, 2022
|
|