8IKV
 
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8IKM
 | | Trans complex of phospho parkin | | Descriptor: | DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... | | Authors: | Lenka, D.R, Kumar, A. | | Deposit date: | 2023-02-28 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Additional feedforward mechanism of Parkin activation via binding of phospho-UBL and RING0 in trans.
Elife, 13, 2024
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8IKT
 | | Ternary trans-complex of phospho-parkin with cis ACT and pUb | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-AMINOPROPANE, E3 ubiquitin-protein ligase parkin, ... | | Authors: | Lenka, D.R, Kumar, A. | | Deposit date: | 2023-03-01 | | Release date: | 2024-09-11 | | Last modified: | 2024-09-18 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Additional feedforward mechanism of Parkin activation via binding of phospho-UBL and RING0 in trans.
Elife, 13, 2024
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8JWV
 | | Untethered R0RBR | | Descriptor: | BARIUM ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... | | Authors: | Lenka, D.R, Kumar, A. | | Deposit date: | 2023-06-29 | | Release date: | 2024-07-03 | | Last modified: | 2024-09-18 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Additional feedforward mechanism of Parkin activation via binding of phospho-UBL and RING0 in trans.
Elife, 13, 2024
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8IK6
 | | pUbl depleted Parkin complex with pUbiquitin | | Descriptor: | E3 ubiquitin-protein ligase parkin, SULFATE ION, Ubiquitin, ... | | Authors: | Lenka, D.R, Kumar, A. | | Deposit date: | 2023-02-28 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Additional feedforward mechanism of Parkin activation via binding of phospho-UBL and RING0 in trans.
Elife, 13, 2024
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8WZN
 | | ParkinK211N in complex with phospho NEDD8 | | Descriptor: | DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase parkin, NEDD8, ... | | Authors: | Lenka, D.R, Kumar, A. | | Deposit date: | 2023-11-02 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Parkin in complex with phospho NEDD8
Structure
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8WZO
 | | Parkin in complex with phospho NEDD8 | | Descriptor: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase parkin, NEDD8, ... | | Authors: | Lenka, D.R, Kumar, A. | | Deposit date: | 2023-11-02 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Parkin in complex with phospho NEDD8
Structure
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7XQ7
 | | The complex structure of WT-Mpro | | Descriptor: | 3C-like proteinase nsp5, SODIUM ION | | Authors: | Sahoo, P, Lenka, D.R, Kumar, A. | | Deposit date: | 2022-05-06 | | Release date: | 2023-03-01 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Detailed Insights into the Inhibitory Mechanism of New Ebselen Derivatives against Main Protease (M pro ) of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2).
Acs Pharmacol Transl Sci, 6, 2023
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7XQ6
 | | The complex structure of mutant Mpro with inhibitor | | Descriptor: | 3C-like proteinase nsp5, CHLORIDE ION | | Authors: | Sahoo, P, Lenka, D.R, Kumar, A. | | Deposit date: | 2022-05-06 | | Release date: | 2023-03-01 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Detailed Insights into the Inhibitory Mechanism of New Ebselen Derivatives against Main Protease (M pro ) of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2).
Acs Pharmacol Transl Sci, 6, 2023
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7W9G
 | | Complex structure of Mpro with ebselen-derivative inhibitor | | Descriptor: | 3C-like proteinase nsp5, SELENIUM ATOM | | Authors: | Sahoo, P, Kumar, A. | | Deposit date: | 2021-12-09 | | Release date: | 2022-12-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Detailed Insights into the Inhibitory Mechanism of New Ebselen Derivatives against Main Protease (M pro ) of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2).
Acs Pharmacol Transl Sci, 6, 2023
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