1LK3
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![BU of 1lk3 by Molmil](/molmil-images/mine/1lk3) | ENGINEERED HUMAN INTERLEUKIN-10 MONOMER COMPLEXED TO 9D7 FAB FRAGMENT | Descriptor: | 9D7 Heavy Chain, 9D7 Light Chain, Interleukin-10 | Authors: | Josephson, K, Jones, B.C, Walter, L.J, DiGiacomo, R, Indelicato, S.R, Walter, M.R. | Deposit date: | 2002-04-23 | Release date: | 2002-07-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Noncompetitive antibody neutralization of IL-10 revealed by protein engineering and x-ray crystallography. Structure, 10, 2002
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1J7V
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![BU of 1j7v by Molmil](/molmil-images/mine/1j7v) | HUMAN IL-10 / IL-10R1 COMPLEX | Descriptor: | INTERLEUKIN-10, INTERLEUKIN-10 RECEPTOR ALPHA CHAIN | Authors: | Josephson, K, Logsdon, N, Walter, M.R. | Deposit date: | 2001-05-18 | Release date: | 2001-09-19 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site. Immunity, 15, 2001
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4JAI
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![BU of 4jai by Molmil](/molmil-images/mine/4jai) | Crystal Structure of Aurora Kinase A in complex with N-{4-[(6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridin-1-yl)amino]phenyl}benzamide | Descriptor: | Aurora kinase A, N-{4-[(6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridin-1-yl)amino]phenyl}benzamide | Authors: | Jiang, X, Josephson, K, Huck, B, Goutopoulos, A, Karra, S. | Deposit date: | 2013-02-18 | Release date: | 2013-05-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
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4JAJ
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![BU of 4jaj by Molmil](/molmil-images/mine/4jaj) | Crystal Structure of Aurora Kinase A in complex with BENZO[C][1,8]NAPHTHYRIDIN-6(5H)-ONE | Descriptor: | Aurora kinase A, benzo[c][1,8]naphthyridin-6(5H)-one | Authors: | Jiang, X, Josephson, K, Huck, B, Goutopoulos, A, Karra, S. | Deposit date: | 2013-02-18 | Release date: | 2013-05-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
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1LQS
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![BU of 1lqs by Molmil](/molmil-images/mine/1lqs) | CRYSTAL STRUCTURE OF HUMAN CYTOMEGALOVIRUS IL-10 BOUND TO SOLUBLE HUMAN IL-10R1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, INTERLEUKIN-10 RECEPTOR ALPHA CHAIN, INTERLEUKIN-10-LIKE PROTEIN | Authors: | Jones, B.C, Logsdon, N.J, Josephson, K, Cook, J, Barry, P.A, Walter, M.R. | Deposit date: | 2002-05-13 | Release date: | 2002-07-17 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1. Proc.Natl.Acad.Sci.USA, 99, 2002
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