Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1DVF
DownloadVisualize
BU of 1dvf by Molmil
IDIOTOPIC ANTIBODY D1.3 FV FRAGMENT-ANTIIDIOTOPIC ANTIBODY E5.2 FV FRAGMENT COMPLEX
Descriptor: FV D1.3, FV E5.2, ZINC ION
Authors:Braden, B.C, Fields, B.A, Ysern, X, Dall'Acqua, W, Goldbaum, F.A, Poljak, R.J, Mariuzza, R.A.
Deposit date:1996-04-13
Release date:1996-08-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of an Fv-Fv idiotope-anti-idiotope complex at 1.9 A resolution.
J.Mol.Biol., 264, 1996
1A2Y
DownloadVisualize
BU of 1a2y by Molmil
HEN EGG WHITE LYSOZYME, D18A MUTANT, IN COMPLEX WITH MOUSE MONOCLONAL ANTIBODY D1.3
Descriptor: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN), LYSOZYME, ...
Authors:Tsuchiya, D, Mariuzza, R.A.
Deposit date:1998-01-13
Release date:1998-04-29
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A mutational analysis of binding interactions in an antigen-antibody protein-protein complex.
Biochemistry, 37, 1998
6ATT
DownloadVisualize
BU of 6att by Molmil
39S Fab bound to HER2 ecd
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 39S Fab heavy chain, ...
Authors:Oganesyan, V.Y, Dall'Acqua, W.F.
Deposit date:2017-08-29
Release date:2018-04-25
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.77 Å)
Cite:Structural insights into the mechanism of action of a biparatopic anti-HER2 antibody.
J. Biol. Chem., 293, 2018
1KIP
DownloadVisualize
BU of 1kip by Molmil
FV MUTANT Y(B 32)A (VH DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME
Descriptor: LYSOZYME, MONOCLONAL ANTIBODY D1.3
Authors:Fields, B.A, Poljak, R.J, Mariuzza, R.A.
Deposit date:1996-10-23
Release date:1996-12-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme.
Biochemistry, 35, 1996
1KIQ
DownloadVisualize
BU of 1kiq by Molmil
FV MUTANT Y(B 101)F (VH DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME
Descriptor: LYSOZYME, MONOCLONAL ANTIBODY D1.3
Authors:Fields, B.A, Poljak, R.J, Mariuzza, R.A.
Deposit date:1996-10-23
Release date:1996-12-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme.
Biochemistry, 35, 1996
1KIR
DownloadVisualize
BU of 1kir by Molmil
FV MUTANT Y(A 50)S (VL DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME
Descriptor: LYSOZYME, MONOCLONAL ANTIBODY D1.3
Authors:Fields, B.A, Poljak, R.J, Mariuzza, R.A.
Deposit date:1996-10-23
Release date:1996-12-23
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme.
Biochemistry, 35, 1996
4UB0
DownloadVisualize
BU of 4ub0 by Molmil
New design for monovalent bispecific IgG through cysteine engineering of the CH1-CL interface
Descriptor: IgG1, heavy chain, light chain
Authors:Oganesyan, V.Y, Dall'Acqua, W.F.
Deposit date:2014-08-11
Release date:2015-07-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Improving target cell specificity using a novel monovalent bispecific IgG design.
Mabs, 7, 2015
6WIB
DownloadVisualize
BU of 6wib by Molmil
Next generation monomeric IgG4 Fc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin heavy constant gamma 4, ZINC ION
Authors:Oganesyan, V.Y, Shan, L, Dall'Acqua, W, van Dyk, N.
Deposit date:2020-04-09
Release date:2021-09-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Commun Biol, 4, 2021
1VFB
DownloadVisualize
BU of 1vfb by Molmil
BOUND WATER MOLECULES AND CONFORMATIONAL STABILIZATION HELP MEDIATE AN ANTIGEN-ANTIBODY ASSOCIATION
Descriptor: HEN EGG WHITE LYSOZYME, IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN)
Authors:Bhat, T.N, Poljak, R.J.
Deposit date:1993-12-03
Release date:1994-05-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Bound water molecules and conformational stabilization help mediate an antigen-antibody association.
Proc.Natl.Acad.Sci.USA, 91, 1994
1VFA
DownloadVisualize
BU of 1vfa by Molmil
BOUND WATER MOLECULES AND CONFORMATIONAL STABILIZATION HELP MEDIATE AN ANTIGEN-ANTIBODY ASSOCIATION
Descriptor: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN)
Authors:Bhat, T.N, Poljak, R.J.
Deposit date:1993-12-03
Release date:1994-05-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Bound water molecules and conformational stabilization help mediate an antigen-antibody association.
Proc.Natl.Acad.Sci.USA, 91, 1994
1A7N
DownloadVisualize
BU of 1a7n by Molmil
FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) VARIANT FOR CHAIN L GLU81->ASP AND CHAIN H LEU312->VAL
Descriptor: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN)
Authors:Marks, C, Henrick, K, Winter, G.
Deposit date:1998-03-16
Release date:1998-04-29
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:X-Ray Structures of D1.3 Fv Mutants
To be Published
1A7Q
DownloadVisualize
BU of 1a7q by Molmil
FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) HIGH AFFINITY EXPRESSED VARIANT CONTAINING SER26L->GLY, ILE29L->THR, GLU81L->ASP, THR97L->SER, PRO240H->LEU, ASP258H->ALA, LYS281H->GLU, ASN283H->ASP AND LEU312H->VAL
Descriptor: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN)
Authors:Marks, C, Henrick, K, Winter, G.
Deposit date:1998-03-16
Release date:1998-04-29
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-Ray Structures of D1.3 Fv Mutants
To be Published
1A7O
DownloadVisualize
BU of 1a7o by Molmil
FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) R96L DELETION MUTANT ON VARIANT FOR CHAIN L GLU81->ASP AND CHAIN H LEU312->VAL
Descriptor: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN)
Authors:Marks, C, Henrick, K, Winter, G.
Deposit date:1998-03-16
Release date:1998-04-29
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-Ray Structures of D1.3 Fv Mutants
To be Published
1A7R
DownloadVisualize
BU of 1a7r by Molmil
FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) VARIANT CHAIN L GLU81->ASP
Descriptor: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN)
Authors:Marks, C, Henrick, K, Winter, G.
Deposit date:1998-03-16
Release date:1998-04-29
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:X-Ray Structures of D1.3 Fv Mutants
To be Published
1A7P
DownloadVisualize
BU of 1a7p by Molmil
FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) ENGINEERED MUTANT PRO95L->SER ON VARIANT CHAIN L GLU81->ASP AND CHAIN H LEU312->VAL
Descriptor: ACETIC ACID, IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN)
Authors:Marks, C, Henrick, K, Winter, G.
Deposit date:1998-03-16
Release date:1998-04-29
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:X-Ray Structures of D1.3 Fv Mutants
To be Published

226707

건을2024-10-30부터공개중

PDB statisticsPDBj update infoContact PDBjnumon