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4ECA
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BU of 4eca by Molmil
ASPARAGINASE FROM E. COLI, MUTANT T89V WITH COVALENTLY BOUND ASPARTATE
Descriptor: L-ASPARAGINE AMIDOHYDROLASE
Authors:Palm, G.J, Lubkowski, J, Wlodawer, A.
Deposit date:1997-02-21
Release date:1997-06-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A covalently bound catalytic intermediate in Escherichia coli asparaginase: crystal structure of a Thr-89-Val mutant.
FEBS Lett., 390, 1996
4EXH
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BU of 4exh by Molmil
The crystal structure of xmrv protease complexed with acetyl-pepstatin
Descriptor: ACETYL-PEPSTATIN, FORMIC ACID, Putative gag-pro-pol polyprotein
Authors:Li, M, Wlodawer, A.
Deposit date:2012-04-30
Release date:2012-08-01
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inhibition of XMRV and HIV-1 proteases by pepstatin A and acetyl-pepstatin.
Febs J., 279, 2012
6WZ8
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BU of 6wz8 by Molmil
Complex of Pseudomonas 7A Glutaminase-Asparaginase with Citrate Anion at pH 5.5. Covalent Acyl-Enzyme Intermediate
Descriptor: CITRIC ACID, Glutaminase-asparaginase
Authors:Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J.
Deposit date:2020-05-13
Release date:2020-10-14
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
6WYY
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BU of 6wyy by Molmil
Crystal structure of Pseudomonas 7A Glutaminase-Asparaginase in complex with L-Glu at pH 6.5
Descriptor: 1,2-ETHANEDIOL, GLUTAMIC ACID, GLYCEROL, ...
Authors:Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J.
Deposit date:2020-05-13
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
6X5M
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BU of 6x5m by Molmil
Crystal structure of a stabilized PAN ENE bimolecular triplex with a GC-clamped polyA tail, in complex with Fab-BL-3,6.
Descriptor: Heavy chain Fab Bl-3 6, Light chain Fab BL-3 6, SULFATE ION, ...
Authors:Swain, M, Li, M, Wlodawer, A, Le Grice, S.F.J.
Deposit date:2020-05-26
Release date:2020-06-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dynamic bulge nucleotides in the KSHV PAN ENE triple helix provide a unique binding platform for small molecule ligands.
Nucleic Acids Res., 49, 2021
6WZ4
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BU of 6wz4 by Molmil
Complex of mutant (K173M) of Pseudomonas 7A Glutaminase-Asparaginase with L-Asp at pH 6. Covalent acyl-enzyme intermediate
Descriptor: ASPARTIC ACID, Glutaminase-asparaginase
Authors:Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J.
Deposit date:2020-05-13
Release date:2020-10-14
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
6WYZ
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BU of 6wyz by Molmil
Crystal structure of Pseudomonas 7A Glutaminase-Asparaginase (mutant K173M) in complex with D-Glu at pH 5.5
Descriptor: D-GLUTAMIC ACID, Glutaminase-asparaginase
Authors:Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J.
Deposit date:2020-05-13
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
1HFK
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BU of 1hfk by Molmil
Asparaginase from Erwinia chrysanthemi, hexagonal form with weak sulfate
Descriptor: L-ASPARAGINE AMIDOHYDROLASE, SULFATE ION
Authors:Lubkowski, J, Palm, G.J, Kozak, M, Jaskolski, M, Wlodawer, A.
Deposit date:2000-12-05
Release date:2000-12-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structures of Two Highly Homologous Bacterial L-Asparaginases: A Case of Enantiomorphic Space Groups
Acta Crystallogr.,Sect.D, 57, 2001
6RIZ
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BU of 6riz by Molmil
Crystal structure of gp41-1 intein (C1A, F65W, D107C)
Descriptor: gp41-1 intein
Authors:Beyer, H.M, Lountos, G.T, Mikula, M.K, Wlodawer, A, Iwai, H.
Deposit date:2019-04-25
Release date:2020-04-29
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The Convergence of the Hedgehog/Intein Fold in Different Protein Splicing Mechanisms.
Int J Mol Sci, 21, 2020
6RIX
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BU of 6rix by Molmil
Crystal structure of MchDnaB-1 intein
Descriptor: CHLORIDE ION, Replicative DNA helicase
Authors:Beyer, H.M, Lountos, G.T, Mikula, M.K, Wlodawer, A, Iwai, H.
Deposit date:2019-04-25
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.655 Å)
Cite:The Convergence of the Hedgehog/Intein Fold in Different Protein Splicing Mechanisms.
Int J Mol Sci, 21, 2020
6RIY
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BU of 6riy by Molmil
Crystal structure of MchDnaB-1 intein (N145AA)
Descriptor: CHLORIDE ION, Replicative DNA helicase
Authors:Beyer, H.M, Lountos, G.T, Mikula, M.K, Wlodawer, A, Iwai, H.
Deposit date:2019-04-25
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:The Convergence of the Hedgehog/Intein Fold in Different Protein Splicing Mechanisms.
Int J Mol Sci, 21, 2020
5NBK
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BU of 5nbk by Molmil
NDM-1 metallo-beta-lactamase: a parsimonious interpretation of the diffraction data
Descriptor: CHLORIDE ION, HEXAETHYLENE GLYCOL, Metallo-beta-lactamase type 2, ...
Authors:Raczynska, J.E, Shabalin, I.G, Jaskolski, M, Minor, W, Wlodawer, A.
Deposit date:2017-03-02
Release date:2018-10-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A close look onto structural models and primary ligands of metallo-beta-lactamases.
Drug Resist. Updat., 40, 2018
1HFJ
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BU of 1hfj by Molmil
Asparaginase from Erwinia chrysanthemi, hexagonal form with sulfate
Descriptor: L-ASPARAGINE AMIDOHYDROLASE, SULFATE ION
Authors:Palm, G.J, Lubkowski, J, Kozak, M, Jaskolski, M, Wlodawer, A.
Deposit date:2000-12-05
Release date:2000-12-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of Two Highly Homologous Bacterial L-Asparaginases: A Case of Enantiomorphic Space Groups
Acta Crystallogr.,Sect.D, 57, 2001
6WZ6
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BU of 6wz6 by Molmil
Complex of mutant (K173M) of Pseudomonas 7A Glutaminase-Asparaginase with L-Glu at pH 5. Covalent acyl-enzyme intermediate
Descriptor: 1,2-ETHANEDIOL, GLUTAMIC ACID, Glutaminase-asparaginase
Authors:Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J.
Deposit date:2020-05-13
Release date:2020-10-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
6N2I
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BU of 6n2i by Molmil
Lon protease AAA+ domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA-binding ATP-dependent protease La
Authors:Botos, I, Li, M, Wlodawer, A, Gustchina, A.
Deposit date:2018-11-13
Release date:2019-07-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:New insights into structural and functional relationships between LonA proteases and ClpB chaperones.
Febs Open Bio, 9, 2019
1JSR
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BU of 1jsr by Molmil
CRYSTAL STRUCTURE OF ERWINIA CHRYSANTHEMI L-ASPARAGINASE COMPLEXED WITH 6-HYDROXY-L-NORLEUCINE
Descriptor: 6-HYDROXY-L-NORLEUCINE, GLYCEROL, L-asparaginase, ...
Authors:Aghaiypour, K, Wlodawer, A, Lubkowski, J.
Deposit date:2001-08-17
Release date:2002-01-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Do bacterial L-asparaginases utilize a catalytic triad Thr-Tyr-Glu?
Biochim.Biophys.Acta, 1550, 2001
6WYW
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BU of 6wyw by Molmil
Crystal structure of Pseudomonas 7A Glutaminase-Asparaginase in complex with L-Asp at pH 4.5
Descriptor: ASPARTIC ACID, Glutaminase-asparaginase
Authors:Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J.
Deposit date:2020-05-13
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
6WYX
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BU of 6wyx by Molmil
Crystal structure of Pseudomonas 7A Glutaminase-Asparaginase in complex with L-Asp at pH 5.0
Descriptor: ASPARTIC ACID, GLYCEROL, Glutaminase-asparaginase
Authors:Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J.
Deposit date:2020-05-13
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
1JSL
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BU of 1jsl by Molmil
Crystal structure of Erwinia chrysanthemi L-asparaginase complexed with 6-HYDROXY-D-NORLEUCINE
Descriptor: 6-HYDROXY-D-NORLEUCINE, GLYCEROL, L-asparaginase, ...
Authors:Aghaiypour, K, Wlodawer, A, Lubkowski, J.
Deposit date:2001-08-17
Release date:2002-01-09
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Do bacterial L-asparaginases utilize a catalytic triad Thr-Tyr-Glu?
Biochim.Biophys.Acta, 1550, 2001
1HFW
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BU of 1hfw by Molmil
X-ray structure of the complex between Erwinia chrysanthemi L-asparaginase and L-Glutamate
Descriptor: GLUTAMIC ACID, L-ASPARAGINASE
Authors:Lubkowski, J, Wlodawer, A, Kolyani, K.A.
Deposit date:2000-12-08
Release date:2001-08-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Stuctural Basis for the Activity and Substrate Specificity of Erwinia Chrysanthemi L-Asparaginase
Biochemistry, 40, 2001
6V25
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BU of 6v25 by Molmil
Complex of mutant (K162M) of E. coli L-asparaginase II with L-Asp
Descriptor: ASPARTIC ACID, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-11-22
Release date:2020-05-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020
6V24
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BU of 6v24 by Molmil
Complex of mutant (K162M) of E. coli L-asparaginase II with L-Asp. Covalent acyl-enzyme intermediate.
Descriptor: ASPARTIC ACID, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-11-22
Release date:2020-05-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020
6V2G
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BU of 6v2g by Molmil
Complex of mutant (K162M) of E. coli L-asparaginase II with L-Asp. Covalent acyl-enzyme intermediate and tetrahedral intermediate.
Descriptor: L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-11-22
Release date:2020-05-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020
6V23
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BU of 6v23 by Molmil
Ligand-free L-aspraginase II from E. coli (EcAII)
Descriptor: L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-11-22
Release date:2020-05-20
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020
6V2B
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BU of 6v2b by Molmil
Complex of double mutant (T89V,K162T) of E. coli L-asparaginase II with L-Asn
Descriptor: ASPARAGINE, CITRIC ACID, L-asparaginase 2
Authors:Lubkowski, J, Wlodawer, A.
Deposit date:2019-11-22
Release date:2020-05-20
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020

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