2GS2
| Crystal Structure of the active EGFR kinase domain | Descriptor: | Epidermal growth factor receptor | Authors: | Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J. | Deposit date: | 2006-04-25 | Release date: | 2006-06-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. Cell(Cambridge,Mass.), 125, 2006
|
|
1HQK
| CRYSTAL STRUCTURE ANALYSIS OF LUMAZINE SYNTHASE FROM AQUIFEX AEOLICUS | Descriptor: | 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE | Authors: | Zhang, X, Meining, W, Fischer, M, Bacher, A, Ladenstein, R. | Deposit date: | 2000-12-18 | Release date: | 2001-12-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | X-ray structure analysis and crystallographic refinement of lumazine synthase from the hyperthermophile Aquifex aeolicus at 1.6 A resolution: determinants of thermostability revealed from structural comparisons. J.Mol.Biol., 306, 2001
|
|
8HI5
| |
8HI6
| |
3IYL
| Atomic CryoEM Structure of a Nonenveloped Virus Suggests How Membrane Penetration Protein is Primed for Cell Entry | Descriptor: | Core protein VP6, MYRISTIC ACID, Outer capsid VP4, ... | Authors: | Zhang, X, Jin, L, Fang, Q, Hui, W, Zhou, Z.H. | Deposit date: | 2010-02-02 | Release date: | 2010-05-12 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | 3.3 A cryo-EM structure of a nonenveloped virus reveals a priming mechanism for cell entry. Cell(Cambridge,Mass.), 141, 2010
|
|
5XBM
| Structure of SCARB2-JL2 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosome membrane protein 2, ... | Authors: | Zhang, X, Yang, P, Wang, N, Zhang, J, Li, J, Guo, H, Yin, X, Rao, Z, Wang, X, Zhang, L. | Deposit date: | 2017-03-20 | Release date: | 2018-06-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.501 Å) | Cite: | The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection. Protein Cell, 8, 2017
|
|
1KJS
| NMR SOLUTION STRUCTURE OF C5A AT PH 5.2, 303K, 20 STRUCTURES | Descriptor: | C5A | Authors: | Zhang, X, Boyar, W, Toth, M, Wennogle, L, Gonnella, N.C. | Deposit date: | 1997-01-09 | Release date: | 1997-05-15 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Structural definition of the C5a C terminus by two-dimensional nuclear magnetic resonance spectroscopy. Proteins, 28, 1997
|
|
3J4U
| A new topology of the HK97-like fold revealed in Bordetella bacteriophage: non-covalent chainmail secured by jellyrolls | Descriptor: | cementing protein, major capsid protein | Authors: | Zhang, X, Guo, H, Jin, L, Czornyj, E, Hodes, A, Hui, W.H, Nieh, A.W, Miller, J.F, Zhou, Z.H. | Deposit date: | 2013-10-09 | Release date: | 2013-12-25 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | A new topology of the HK97-like fold revealed in Bordetella bacteriophage by cryoEM at 3.5 A resolution. Elife, 2, 2013
|
|
3F4M
| Crystal structure of TIPE2 | Descriptor: | CHLORIDE ION, Tumor necrosis factor, alpha-induced protein 8-like protein 2 | Authors: | Zhang, X, Wang, J, Shi, Y. | Deposit date: | 2008-11-01 | Release date: | 2009-03-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.696 Å) | Cite: | Crystal structure of TIPE2 provides insights into immune homeostasis Nat.Struct.Mol.Biol., 16, 2009
|
|
5YB3
| Crystal structure of HP23L/N36 | Descriptor: | Envelope glycoprotein, HP23L | Authors: | Zhang, X, Wang, X, He, Y. | Deposit date: | 2017-09-03 | Release date: | 2018-02-28 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.043 Å) | Cite: | Structural Insights into the Mechanisms of Action of Short-Peptide HIV-1 Fusion Inhibitors Targeting the Gp41 Pocket Front Cell Infect Microbiol, 8, 2018
|
|
5YB2
| Crystal structure of LP-11/N44 | Descriptor: | Envelope glycoprotein, LP-11 | Authors: | Zhang, X, Wang, X, He, Y. | Deposit date: | 2017-09-03 | Release date: | 2018-02-28 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural Insights into the Mechanisms of Action of Short-Peptide HIV-1 Fusion Inhibitors Targeting the Gp41 Pocket Front Cell Infect Microbiol, 8, 2018
|
|
5YB4
| Crystal structure of HP23LN36KR | Descriptor: | HP23L, N36KR | Authors: | Zhang, X, Wang, X, He, Y. | Deposit date: | 2017-09-03 | Release date: | 2018-02-28 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Insights into the Mechanisms of Action of Short-Peptide HIV-1 Fusion Inhibitors Targeting the Gp41 Pocket Front Cell Infect Microbiol, 8, 2018
|
|
1E32
| Structure of the N-Terminal domain and the D1 AAA domain of membrane fusion ATPase p97 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, P97 | Authors: | Zhang, X, Shaw, A, Bates, P.A, Gorman, M.A, Kondo, H, Dokurno, P, Leonard M, G, Sternberg, J.E, Freemont, P.S. | Deposit date: | 2000-06-05 | Release date: | 2001-05-31 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of the Aaa ATPase P97 Mol.Cell, 6, 2000
|
|
1CDZ
| BRCT DOMAIN FROM DNA-REPAIR PROTEIN XRCC1 | Descriptor: | PROTEIN (DNA-REPAIR PROTEIN XRCC1) | Authors: | Zhang, X, Morera, S, Bates, P, Whitehead, P, Coffer, A, Hainbucher, K, Nash, R, Sternberg, M, Lindahl, T, Freemont, P. | Deposit date: | 1999-03-04 | Release date: | 2000-02-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure of an XRCC1 BRCT domain: a new protein-protein interaction module. EMBO J., 17, 1998
|
|
5ZMD
| Crystal structure of FTO in complex with m6dA modified ssDNA | Descriptor: | Alpha-ketoglutarate-dependent dioxygenase FTO, DNA (5'-D(P*TP*CP*TP*(6MA)P*TP*AP*TP*CP*G)-3'), MANGANESE (II) ION, ... | Authors: | Zhang, X, Wei, L.H, Luo, J, Xiao, Y, Liu, J, Zhang, W, Zhang, L, Jia, G.F. | Deposit date: | 2018-04-02 | Release date: | 2019-04-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural insights into FTO's catalytic mechanism for the demethylation of multiple RNA substrates. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
|
|
1EUB
| SOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN COLLAGENASE-3 (MMP-13) COMPLEXED TO A POTENT NON-PEPTIDIC SULFONAMIDE INHIBITOR | Descriptor: | 1-METHYLOXY-4-SULFONE-BENZENE, 3-METHYLPYRIDINE, CALCIUM ION, ... | Authors: | Zhang, X, Gonnella, N.C, Koehn, J, Pathak, N, Ganu, V, Melton, R, Parker, D, Hu, S.I, Nam, K.Y. | Deposit date: | 2000-04-14 | Release date: | 2001-04-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the catalytic domain of human collagenase-3 (MMP-13) complexed to a potent non-peptidic sulfonamide inhibitor: binding comparison with stromelysin-1 and collagenase-1. J.Mol.Biol., 301, 2000
|
|
4KSY
| |
6AHF
| CryoEM Reconstruction of Hsp104 N728A Hexamer | Descriptor: | Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Zhang, X, Zhang, L, Zhang, S. | Deposit date: | 2018-08-17 | Release date: | 2019-02-13 | Last modified: | 2019-04-10 | Method: | ELECTRON MICROSCOPY (6.78 Å) | Cite: | Heat shock protein 104 (HSP104) chaperones soluble Tau via a mechanism distinct from its disaggregase activity. J. Biol. Chem., 294, 2019
|
|
1CFA
| SOLUTION STRUCTURE OF A SEMI-SYNTHETIC C5A RECEPTOR ANTAGONIST AT PH 5.2, 303K, NMR, 20 STRUCTURES | Descriptor: | COMPLEMENT 5A SEMI-SYNTHETIC ANTAGONIST, SYNTHETIC N-TERMINAL TAIL | Authors: | Zhang, X, Boyar, W, Galakatos, N, Gonnella, N.C. | Deposit date: | 1996-09-21 | Release date: | 1997-09-17 | Last modified: | 2024-06-05 | Method: | SOLUTION NMR | Cite: | Solution structure of a unique C5a semi-synthetic antagonist: implications in receptor binding. Protein Sci., 6, 1997
|
|
7W5B
| The cryo-EM structure of human C* complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
|
|
7W5A
| The cryo-EM structure of human pre-C*-II complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
|
|
7W59
| The cryo-EM structure of human pre-C*-I complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
|
|
6J4A
| |
7KI0
| Semaglutide-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in Complex with Gs protein | Descriptor: | 17-amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecan-1-oic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhang, X, Belousoff, M.J, Danev, R, Sexton, P.M, Wootten, D. | Deposit date: | 2020-10-22 | Release date: | 2021-08-04 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes. Cell Rep, 36, 2021
|
|
7KI1
| Taspoglutide-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in Complex with Gs Protein | Descriptor: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhang, X, Belousoff, M.J, Danev, R, Sexton, P.M, Wootten, D. | Deposit date: | 2020-10-22 | Release date: | 2021-08-04 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes. Cell Rep, 36, 2021
|
|