2F9A
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![BU of 2f9a by Molmil](/molmil-images/mine/2f9a) | HMG-CoA synthase from Brassica juncea in complex with F-244 | Descriptor: | (7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid, 3-Hydroxy-3-methylglutaryl coenzyme A synthase 1 | Authors: | Pojer, F, Ferrer, J.L, Richard, S.B, Noel, J.P. | Deposit date: | 2005-12-05 | Release date: | 2006-07-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structural basis for the design of potent and species-specific inhibitors of 3-hydroxy-3-methylglutaryl CoA synthases. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2FA0
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![BU of 2fa0 by Molmil](/molmil-images/mine/2fa0) | HMG-CoA synthase from Brassica juncea in complex with HMG-CoA and covalently bound to HMG-CoA | Descriptor: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, HMG-CoA synthase | Authors: | Pojer, F, Ferrer, J.L, Richard, S.B, Noel, J.P. | Deposit date: | 2005-12-06 | Release date: | 2006-07-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structural basis for the design of potent and species-specific inhibitors of 3-hydroxy-3-methylglutaryl CoA synthases. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2O7B
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![BU of 2o7b by Molmil](/molmil-images/mine/2o7b) | Tyrosine ammonia-lyase from Rhodobacter sphaeroides, complexed with coumarate | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Putative histidine ammonia-lyase | Authors: | Louie, G.V, Bowman, M.E, Moffitt, M.C, Baiga, T.J, Moore, B.S, Noel, J.P. | Deposit date: | 2006-12-10 | Release date: | 2007-01-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases. Chem.Biol., 13, 2006
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2O7F
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![BU of 2o7f by Molmil](/molmil-images/mine/2o7f) | Tyrosine ammonia-lyase from Rhodobacter sphaeroides (His89Phe variant), complexed with coumaric acid | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Putative histidine ammonia-lyase | Authors: | Louie, G.V, Bowman, M.E, Moffitt, M.C, Baiga, T.J, Moore, B.S, Noel, J.P. | Deposit date: | 2006-12-11 | Release date: | 2007-01-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases. Chem.Biol., 13, 2006
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2O78
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![BU of 2o78 by Molmil](/molmil-images/mine/2o78) | Tyrosine ammonia-lyase from Rhodobacter sphaeroides (His89Phe variant) complexed with cinnamic acid | Descriptor: | PHENYLETHYLENECARBOXYLIC ACID, Putative histidine ammonia-lyase | Authors: | Louie, G.V, Bowman, M.E, Moffitt, M.C, Baiga, T.J, Moore, B.S, Noel, J.P. | Deposit date: | 2006-12-10 | Release date: | 2007-01-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases. Chem.Biol., 13, 2006
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2NYF
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![BU of 2nyf by Molmil](/molmil-images/mine/2nyf) | Crystal structure of phenylalanine ammonia-lyase from Nostoc punctiforme | Descriptor: | Nostoc punctiforme phenylalanine ammonia lyase | Authors: | Louie, G.V, Moffitt, M.C, Bowman, M.E, Pence, J, Noel, J.P, Moore, B.S. | Deposit date: | 2006-11-20 | Release date: | 2007-02-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Discovery of Two Cyanobacterial Phenylalanine Ammonia Lyases: Kinetic and Structural Characterization. Biochemistry, 46, 2007
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2O7E
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![BU of 2o7e by Molmil](/molmil-images/mine/2o7e) | Tyrosine ammonia-lyase from Rhodobacter sphaeroides (His89Phe variant), bound to 2-aminoindan-2-phosphonic acid | Descriptor: | (2-AMINO-2,3-DIHYDRO-1H-INDEN-2-YL)PHOSPHONIC ACID, Putative histidine ammonia-lyase | Authors: | Louie, G.V, Bowman, M.E, Moffitt, M.C, Baiga, T.J, Moore, B.S, Noel, J.P. | Deposit date: | 2006-12-11 | Release date: | 2007-01-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases. Chem.Biol., 13, 2006
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2O7D
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![BU of 2o7d by Molmil](/molmil-images/mine/2o7d) | Tyrosine ammonia-lyase from Rhodobacter sphaeroides, complexed with caffeate | Descriptor: | CAFFEIC ACID, Putative histidine ammonia-lyase | Authors: | Louie, G.V, Bowman, M.E, Moffitt, M.C, Baiga, T.J, Moore, B.S, Noel, J.P. | Deposit date: | 2006-12-10 | Release date: | 2007-01-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases. Chem.Biol., 13, 2006
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2O6Y
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![BU of 2o6y by Molmil](/molmil-images/mine/2o6y) | Tyrosine ammonia-lyase from Rhodobacter sphaeroides | Descriptor: | Putative histidine ammonia-lyase | Authors: | Louie, G.V, Bowman, M.E, Moffitt, M.C, Baiga, T.J, Moore, B.S, Noel, J.P. | Deposit date: | 2006-12-09 | Release date: | 2007-01-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases. Chem.Biol., 13, 2006
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2NYN
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![BU of 2nyn by Molmil](/molmil-images/mine/2nyn) | Crystal structure of phenylalanine ammonia-lyase from Anabaena variabilis | Descriptor: | Phenylalanine/histidine ammonia-lyase | Authors: | Louie, G.V, Moffitt, M.C, Bowman, M.E, Pence, J, Noel, J.P, Moore, B.S. | Deposit date: | 2006-11-21 | Release date: | 2007-02-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of Two Cyanobacterial Phenylalanine Ammonia Lyases: Kinetic and Structural Characterization. Biochemistry, 46, 2007
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1JX1
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![BU of 1jx1 by Molmil](/molmil-images/mine/1jx1) | Chalcone Isomerase--T48A mutant | Descriptor: | 7-HYDROXY-2-(4-HYDROXY-PHENYL)-CHROMAN-4-ONE, CHALCONE--FLAVONONE ISOMERASE 1, SULFATE ION | Authors: | Jez, J.M, Bowman, M.E, Noel, J.P. | Deposit date: | 2001-09-05 | Release date: | 2002-07-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Role of Hydrogen Bonds in the Reaction Mechanism of Chalcone Isomerase Biochemistry, 41, 2002
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1JX0
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![BU of 1jx0 by Molmil](/molmil-images/mine/1jx0) | Chalcone Isomerase--Y106F mutant | Descriptor: | 7-HYDROXY-2-(4-HYDROXY-PHENYL)-CHROMAN-4-ONE, CHALCONE--FLAVONONE ISOMERASE 1, SULFATE ION | Authors: | Jez, J.M, Bowman, M.E, Noel, J.P. | Deposit date: | 2001-09-05 | Release date: | 2002-07-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Role of Hydrogen Bonds in the Reaction Mechanism of Chalcone Isomerase Biochemistry, 41, 2002
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1ZGD
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![BU of 1zgd by Molmil](/molmil-images/mine/1zgd) | Chalcone Reductase Complexed With NADP+ at 1.7 Angstrom Resolution | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, chalcone reductase | Authors: | Bomati, E.K, Austin, M.B, Bowman, M.E, Dixon, R.A, Noel, J.P. | Deposit date: | 2005-04-21 | Release date: | 2005-06-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural elucidation of chalcone reductase and implications for deoxychalcone biosynthesis J.Biol.Chem., 280, 2005
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1YFO
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1ZGA
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![BU of 1zga by Molmil](/molmil-images/mine/1zga) | Crystal structure of isoflavanone 4'-O-methyltransferase complexed with (+)-6a-hydroxymaackiain | Descriptor: | (6AR,12AR)-6H-[1,3]DIOXOLO[5,6][1]BENZOFURO[3,2-C]CHROMENE-3,6A(12AH)-DIOL, Isoflavanone 4'-O-methyltransferase', S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Liu, C.-J, Deavours, B.E, Richard, S, Ferrer, J.-L, Dixon, R.A, Noel, J.P. | Deposit date: | 2005-04-20 | Release date: | 2006-08-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural basis for dual functionality of isoflavonoid O-methyltransferases in the evolution of plant defense responses. Plant Cell, 18, 2006
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1ZB6
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![BU of 1zb6 by Molmil](/molmil-images/mine/1zb6) | Co-Crystal Structure of ORF2 an Aromatic Prenyl Transferase from Streptomyces sp. strain cl190 complexed with GSPP and 1,6-dihydroxynaphtalene | Descriptor: | 1,6-DIHYDROXY NAPHTHALENE, Aromatic prenyltransferase, GERANYL S-THIOLODIPHOSPHATE, ... | Authors: | Kuzuyama, T, Noel, J.P, Richard, S.B. | Deposit date: | 2005-04-07 | Release date: | 2005-06-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products. Nature, 435, 2005
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1ZCN
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![BU of 1zcn by Molmil](/molmil-images/mine/1zcn) | human Pin1 Ng mutant | Descriptor: | PENTAETHYLENE GLYCOL, PHOSPHATE ION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Authors: | Jager, M, Zhang, Y, Nguyen, H, Dendel, G, Bowman, M.E, Gruebele, M, Noel, J.P, Kelly, J.W. | Deposit date: | 2005-04-12 | Release date: | 2006-06-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-function-folding relationship in a WW domain. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1ZG3
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![BU of 1zg3 by Molmil](/molmil-images/mine/1zg3) | Crystal structure of the isoflavanone 4'-O-methyltransferase complexed with SAH and 2,7,4'-trihydroxyisoflavanone | Descriptor: | (2S,3R)-2,7-DIHYDROXY-3-(4-HYDROXYPHENYL)-2,3-DIHYDRO-4H-CHROMEN-4-ONE, S-ADENOSYL-L-HOMOCYSTEINE, isoflavanone 4'-O-methyltransferase | Authors: | Liu, C.-J, Deavours, B.E, Richard, S, Ferrer, J.-L, Dixon, R.A, Noel, J.P. | Deposit date: | 2005-04-20 | Release date: | 2006-08-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural basis for dual functionality of isoflavonoid O-methyltransferases in the evolution of plant defense responses. Plant Cell, 18, 2006
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1ZDW
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![BU of 1zdw by Molmil](/molmil-images/mine/1zdw) | Co-crystal structure of Orf2 an aromatic prenyl transferase from Streptomyces sp. strain CL190 complexed with GSPP and Flaviolin | Descriptor: | Aromatic prenyltransferase, FLAVIOLIN, GERANYL S-THIOLODIPHOSPHATE, ... | Authors: | Kuzuyama, T, Noel, J.P, Richard, S.B. | Deposit date: | 2005-04-15 | Release date: | 2005-06-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products. Nature, 435, 2005
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1ZCW
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![BU of 1zcw by Molmil](/molmil-images/mine/1zcw) | Co-crystal structure of Orf2 an aromatic prenyl transferase from Streptomyces sp. strain CL190 complexed with GPP | Descriptor: | Aromatic prenyltransferase, GERANYL DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Kuzuyama, T, Noel, J.P, Richard, S.B. | Deposit date: | 2005-04-13 | Release date: | 2005-06-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products. Nature, 435, 2005
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1ZGJ
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![BU of 1zgj by Molmil](/molmil-images/mine/1zgj) | Crystal structure of isoflavanone 4'-O-methyltransferase complexed with (+)-pisatin | Descriptor: | (6AR,12AR)-3-(HYDROXYMETHYL)-6H-[1,3]DIOXOLO[5,6][1]BENZOFURO[3,2-C]CHROMEN-6A(12AH)-OL, Isoflavanone 4'-O-methyltransferase', S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Liu, C.-J, Deavours, B.E, Richard, S, Ferrer, J.-L, Dixon, R.A, Noel, J.P. | Deposit date: | 2005-04-21 | Release date: | 2006-08-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for dual functionality of isoflavonoid O-methyltransferases in the evolution of plant defense responses. Plant Cell, 18, 2006
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1ZDY
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1ZHF
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![BU of 1zhf by Molmil](/molmil-images/mine/1zhf) | Crystal structure of selenomethionine substituted isoflavanone 4'-O-methyltransferase | Descriptor: | Isoflavanone 4'-O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Liu, C.-J, Deavours, B.E, Richard, S, Ferrer, J.-L, Dixon, R.A, Noel, J.P. | Deposit date: | 2005-04-25 | Release date: | 2006-08-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for dual functionality of isoflavonoid O-methyltransferases in the evolution of plant defense responses. Plant Cell, 18, 2006
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3STX
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![BU of 3stx by Molmil](/molmil-images/mine/3stx) | |
3STY
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![BU of 3sty by Molmil](/molmil-images/mine/3sty) | |