3QPK
| Probing oxygen channels in Melanocarpus albomyces laccase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Kallio, J.P, Rouvinen, J, Hakulinen, N. | Deposit date: | 2011-02-14 | Release date: | 2011-05-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing the Dioxygen Route in Melanocarpus albomyces Laccase with Pressurized Xenon Gas. Biochemistry, 50, 2011
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3FU8
| Melanocarpus albomyces laccase crystal soaked (10 sec) with 2,6-dimethoxyphenol | Descriptor: | 2,6-dimethoxyphenol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kallio, J.P, Hakulinen, N, Rouvinen, J. | Deposit date: | 2009-01-14 | Release date: | 2009-09-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure-Function Studies of a Melanocarpus albomyces Laccase Suggest a Pathway for Oxidation of Phenolic Compounds. J.Mol.Biol., 392, 2009
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3FU9
| Melanocarpus albomyces laccase crystal soaked (20 min) with 2,6-dimethoxyphenol | Descriptor: | 2,6-dimethoxybenzene-1,4-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kallio, J.P, Hakulinen, N, Rouvinen, J. | Deposit date: | 2009-01-14 | Release date: | 2009-09-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-Function Studies of a Melanocarpus albomyces Laccase Suggest a Pathway for Oxidation of Phenolic Compounds. J.Mol.Biol., 392, 2009
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2R56
| Crystal Structure of a Recombinant IgE Fab Fragment in Complex with Bovine Beta-Lactoglobulin Allergen | Descriptor: | Beta-lactoglobulin, DODECYL-BETA-D-MALTOSIDE, IgE Fab Fragment, ... | Authors: | Niemi, M, Kallio, J.M, Hakulinen, N, Rouvinen, J. | Deposit date: | 2007-09-03 | Release date: | 2007-11-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular interactions between a recombinant IgE antibody and the beta-lactoglobulin allergen. Structure, 15, 2007
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3FU7
| Melanocarpus albomyces laccase crystal soaked (4 sec) with 2,6-dimethoxyphenol | Descriptor: | 2,6-dimethoxycyclohexa-2,5-diene-1,4-dione, 2,6-dimethoxyphenol, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kallio, J.P, Hakulinen, N, Rouvinen, J. | Deposit date: | 2009-01-14 | Release date: | 2009-09-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structure Function Studies of a Melanocarpus albomyces Laccase Suggest a Pathway for Oxidation of Phenolic Compounds. J.Mol.Biol., 392, 2009
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3ZZQ
| Engineered 12-subunit Bacillus subtilis trp RNA-binding attenuation protein (TRAP) | Descriptor: | TRANSCRIPTION ATTENUATION PROTEIN MTRB, TRYPTOPHAN | Authors: | Chen, C, Smits, C, Dodson, G.G, Shevtsov, M.B, Merlino, N, Gollnick, P, Antson, A.A. | Deposit date: | 2011-09-02 | Release date: | 2011-10-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | How to Change the Oligomeric State of a Circular Protein Assembly: Switch from 11-Subunit to 12-Subunit Trap Suggests a General Mechanism Plos One, 6, 2011
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3ZZS
| Engineered 12-subunit Bacillus stearothermophilus trp RNA-binding attenuation protein (TRAP) | Descriptor: | TRANSCRIPTION ATTENUATION PROTEIN MTRB, TRYPTOPHAN | Authors: | Chen, C, Smits, C, Dodson, G.G, Shevtsov, M.B, Merlino, N, Gollnick, P, Antson, A.A. | Deposit date: | 2011-09-02 | Release date: | 2011-10-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | How to Change the Oligomeric State of a Circular Protein Assembly: Switch from 11-Subunit to 12-Subunit Trap Suggests a General Mechanism Plos One, 6, 2011
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3ZZL
| Bacillus halodurans trp RNA-binding attenuation protein (TRAP): a 12- subunit assembly | Descriptor: | TRANSCRIPTION ATTENUATION PROTEIN MTRB, TRYPTOPHAN | Authors: | Chen, C, Smits, C, Dodson, G.G, Shevtsov, M.B, Merlino, N, Gollnick, P, Antson, A.A. | Deposit date: | 2011-09-01 | Release date: | 2011-10-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | How to Change the Oligomeric State of a Circular Protein Assembly: Switch from 11-Subunit to 12-Subunit Trap Suggests a General Mechanism Plos One, 6, 2011
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2O8Z
| Bound Structure of CRF1 Extracellular Domain Antagonist | Descriptor: | cCRF(30-41) Peptide | Authors: | Mesleh, M.F, Shirley, W.A, Heise, C.E, Ling, N, Maki, R.A, Laura, R.P. | Deposit date: | 2006-12-12 | Release date: | 2006-12-26 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | NMR structural characterization of a minimal peptide antagonist bound to the extracellular domain of the corticotropin-releasing factor1 receptor. J.Biol.Chem., 282, 2007
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5OYN
| Crystal structure of D-xylonate dehydratase in holo-form | Descriptor: | Dehydratase, IlvD/Edd family, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Rahman, M.M, Rouvinen, J, Hakulinen, N. | Deposit date: | 2017-09-11 | Release date: | 2018-01-24 | Last modified: | 2018-04-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The crystal structure of D-xylonate dehydratase reveals functional features of enzymes from the Ilv/ED dehydratase family. Sci Rep, 8, 2018
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6GS3
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6FG4
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6FHC
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6FGR
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7Q3N
| Cryo-EM of the complex between human uromodulin (UMOD)/Tamm-Horsfall protein (THP) and the FimH lectin domain from uropathogenic E. coli | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Type 1 fimbiral adhesin FimH, ... | Authors: | Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B. | Deposit date: | 2021-10-28 | Release date: | 2022-03-16 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (7.4 Å) | Cite: | Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH. Nat.Struct.Mol.Biol., 29, 2022
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7BYF
| The crystal structure of mouse ORF10-Rae1-Nup98 complex | Descriptor: | 10 protein, MERCURY (II) ION, Peptidase S59 domain-containing protein, ... | Authors: | Gao, P, Feng, H. | Deposit date: | 2020-04-22 | Release date: | 2021-03-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10. Proc.Natl.Acad.Sci.USA, 117, 2020
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5A2T
| The Molecular Basis for Flexibility in the Flexible Filamentous Plant Viruses | Descriptor: | BAMBOO MOSAIC VIRUS, COAT PROTEIN | Authors: | DiMaio, F, Chen, C.C, Yu, X, Frenz, B, Hsu, Y.H, Lin, N.S, Egelman, E.H. | Deposit date: | 2015-05-23 | Release date: | 2015-07-22 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (5.6 Å) | Cite: | The Molecular Basis for Flexibility in the Flexible Filamentous Plant Viruses. Nat.Struct.Mol.Biol., 22, 2015
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6TQL
| Cryo-EM of elastase-treated human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Stsiapanava, A, Xu, C, Carroni, M, Wu, B, Jovine, L. | Deposit date: | 2019-12-16 | Release date: | 2020-11-04 | Last modified: | 2021-03-03 | Method: | ELECTRON MICROSCOPY (3.96 Å) | Cite: | Cryo-EM structure of native human uromodulin, a zona pellucida module polymer. Embo J., 39, 2020
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2IH4
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2IH5
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2IZG
| STREPTAVIDIN-BIOTIN PH 2.0 I222 COMPLEX | Descriptor: | BIOTIN, STREPTAVIDIN, SULFATE ION | Authors: | Katz, B.A. | Deposit date: | 1997-08-13 | Release date: | 1998-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH. J.Mol.Biol., 274, 1997
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7VKB
| Crystal structure of the a bacterial kinase complex | Descriptor: | DI(HYDROXYETHYL)ETHER, HipA (Persistence to inhibition of murein or DNA biosynthesis), HipA_C domain-containing protein, ... | Authors: | Zhen, X, Ouyang, S.Y. | Deposit date: | 2021-09-29 | Release date: | 2022-06-29 | Last modified: | 2022-08-03 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila. Nat Commun, 13, 2022
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7VB8
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7VKC
| Crystal structure of a bacterial Ser/Thr kinase | Descriptor: | HipA_C domain-containing protein | Authors: | Zhen, X, Ouyang, S.Y. | Deposit date: | 2021-09-29 | Release date: | 2022-06-29 | Last modified: | 2022-08-03 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila. Nat Commun, 13, 2022
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7OLX
| MerTK kinase domain with type 1.5 inhibitor containing a tri-methyl pyrazole group | Descriptor: | CHLORIDE ION, Tyrosine-protein kinase Mer, ~{N}-[[3-[4-[(dimethylamino)methyl]phenyl]imidazo[1,2-a]pyridin-6-yl]methyl]-~{N}-methyl-5-[3-methyl-5-(1,3,5-trimethylpyrazol-4-yl)pyridin-2-yl]-1,3,4-oxadiazol-2-amine | Authors: | Pflug, A, Schimpl, M, McCoull, W, Nissink, J.W.M, Winter-Holt, J. | Deposit date: | 2021-05-20 | Release date: | 2021-09-15 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Optimization of an Imidazo[1,2- a ]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy. J.Med.Chem., 64, 2021
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