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6PSU
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BU of 6psu by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi2) with TraR and rpsT P2 promoter
Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-07-13
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
6PSR
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BU of 6psr by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1) with TraR and rpsT P2 promoter
Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-07-13
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
6PSW
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BU of 6psw by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TRPo) with TraR and rpsT P2 promoter
Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-07-13
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
6PSS
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BU of 6pss by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5a) with TraR and mutant rpsT P2 promoter
Descriptor: DNA (85-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-07-13
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
6PSQ
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BU of 6psq by Molmil
Escherichia coli RNA polymerase closed complex (TRPc) with TraR and rpsT P2 promoter
Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-07-13
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
6PST
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BU of 6pst by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5b) with TraR and mutant rpsT P2 promoter
Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-07-13
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
6PSV
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BU of 6psv by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TpreRPo) with TraR and rpsT P2 promoter
Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-07-13
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
6OUL
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BU of 6oul by Molmil
Cryo-EM structure of Escherichia coli RNAP polymerase bound to rpsTP2 promoter DNA
Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-05-04
Release date:2020-02-26
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation.
Elife, 8, 2019
1TH8
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BU of 1th8 by Molmil
Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: inhibitory complex with ADP, crystal form II
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ...
Authors:Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigian, J, Leon, F, Darst, S.A, Campbell, E.A.
Deposit date:2004-06-01
Release date:2004-06-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA.
J.Mol.Biol., 340, 2004
1RIO
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BU of 1rio by Molmil
Structure of bacteriophage lambda cI-NTD in complex with sigma-region4 of Thermus aquaticus bound to DNA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 27-MER, CALCIUM ION, ...
Authors:Jain, D, Nickels, B.E, Sun, L, Hochschild, A, Darst, S.A.
Deposit date:2003-11-17
Release date:2004-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a ternary transcription activation complex.
Mol.Cell, 13, 2004
1RP3
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BU of 1rp3 by Molmil
Cocrystal structure of the flagellar sigma/anti-sigma complex, Sigma-28/FlgM
Descriptor: RNA polymerase sigma factor SIGMA-28 (FliA), anti sigma factor FlgM
Authors:Sorenson, M.K, Ray, S.S, Darst, S.A.
Deposit date:2003-12-02
Release date:2004-04-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the Flagellar Sigma/Anti-Sigma Complex Sigma(28)/FlgM Reveals an Intact Sigma Factor in an Inactive Conformation
Mol.Cell, 14, 2004
1SC5
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BU of 1sc5 by Molmil
Sigma-28(FliA)/FlgM complex
Descriptor: RNA polymerase sigma factor FliA, anti-sigma factor FlgM
Authors:Sorenson, M.K, Ray, S.S, Darst, S.A.
Deposit date:2004-02-11
Release date:2004-04-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Crystal structure of the flagellar sigma/anti-sigma complex sigma(28)/FlgM reveals an intact sigma factor in an inactive conformation.
Mol.Cell, 14, 2004
1THN
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BU of 1thn by Molmil
Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: inhibitory complex with ADP, crystal form I
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ...
Authors:Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigan, J, Leon, F, Darst, S.A, Campbell, E.A.
Deposit date:2004-06-01
Release date:2004-06-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA.
J.Mol.Biol., 340, 2004
1TID
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BU of 1tid by Molmil
Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: Poised for phosphorylation complex with ATP, crystal form I
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ...
Authors:Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigan, J, Leon, F, Darst, S.A, Campbell, E.A.
Deposit date:2004-06-02
Release date:2004-06-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA.
J.Mol.Biol., 340, 2004
1TIL
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BU of 1til by Molmil
Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA:Poised for phosphorylation complex with ATP, crystal form II
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ...
Authors:Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigan, J, Leon, F, Darst, S.A, Campbell, E.A.
Deposit date:2004-06-02
Release date:2004-06-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA.
J.Mol.Biol., 340, 2004
8E8M
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BU of 8e8m by Molmil
Mycobacterium tuberculosis RNAP paused elongation complex
Descriptor: DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Delbeau, M, Darst, S.A, Campbell, E.A.
Deposit date:2022-08-25
Release date:2023-03-22
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
8E79
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BU of 8e79 by Molmil
Mycobacterium tuberculosis RNAP paused elongation complex with Escherichia coli NusG transcription factor
Descriptor: DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Delbeau, M, Darst, S.A, Campbell, E.A.
Deposit date:2022-08-23
Release date:2023-03-22
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
8E95
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BU of 8e95 by Molmil
Mycobacterium tuberculosis RNAP elongation complex
Descriptor: DNA (25-MER), DNA (33-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Delbeau, M, Darst, S.A, Campbell, E.A.
Deposit date:2022-08-26
Release date:2023-03-22
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
8E74
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BU of 8e74 by Molmil
Mycobacterium tuberculosis RNAP paused elongation complex with NusG transcription factor
Descriptor: DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Delbeau, M, Darst, S.A, Campbell, E.A.
Deposit date:2022-08-23
Release date:2023-03-22
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
8E82
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BU of 8e82 by Molmil
Mycobacterium tuberculosis RNAP elongation complex with NusG transcription factor
Descriptor: DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Delbeau, M, Darst, S.A, Campbell, E.A.
Deposit date:2022-08-25
Release date:2023-03-22
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
6ALH
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BU of 6alh by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex
Descriptor: DNA (29-MER), DNA (5'-D(*GP*GP*GP*CP*TP*AP*AP*TP*GP*AP*CP*GP*GP*CP*GP*AP*AP*TP*AP*CP*CP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Kang, J.Y, Darst, S.A.
Deposit date:2017-08-07
Release date:2017-08-16
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural basis of transcription arrest by coliphage HK022 Nun in anEscherichia coliRNA polymerase elongation complex.
Elife, 6, 2017
6ASX
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BU of 6asx by Molmil
CryoEM structure of E.coli his pause elongation complex
Descriptor: DNA (32-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Kang, J.Y, Landick, R, Darst, S.A.
Deposit date:2017-08-25
Release date:2018-03-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:RNA Polymerase Accommodates a Pause RNA Hairpin by Global Conformational Rearrangements that Prolong Pausing.
Mol. Cell, 69, 2018
6CCE
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BU of 6cce by Molmil
Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with inhibitor Kanglemycin A
Descriptor: 1,2-ETHANEDIOL, DNA (57-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lilic, M, Darst, S.A, Campbell, E.A.
Deposit date:2018-02-07
Release date:2018-08-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.
Nat Commun, 9, 2018
6CCV
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BU of 6ccv by Molmil
Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with inhibitor Rifampicin
Descriptor: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ...
Authors:Lilic, M, Darst, S.A, Campbell, E.A.
Deposit date:2018-02-07
Release date:2018-08-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.
Nat Commun, 9, 2018
6C6S
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BU of 6c6s by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound with RfaH
Descriptor: DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Kang, J.Y, Artsimovitch, I, Landick, R, Darst, S.A.
Deposit date:2018-01-19
Release date:2018-07-25
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators.
Cell, 173, 2018

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