7GDC
| Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with LON-WEI-0a73fcb8-7 (Mpro-x10942) | Descriptor: | (4R)-6-chloro-N-[4-(hydroxymethyl)pyridin-3-yl]-3,4-dihydro-2H-1-benzopyran-4-carboxamide, 3C-like proteinase, DIMETHYL SULFOXIDE | Authors: | Fearon, D, Aimon, A, Aschenbrenner, J.C, Balcomb, B.H, Bertram, F.K.R, Brandao-Neto, J, Dias, A, Douangamath, A, Dunnett, L, Godoy, A.S, Gorrie-Stone, T.J, Koekemoer, L, Krojer, T, Lithgo, R.M, Lukacik, P, Marples, P.G, Mikolajek, H, Nelson, E, Owen, C.D, Powell, A.J, Rangel, V.L, Skyner, R, Strain-Damerell, C.M, Thompson, W, Tomlinson, C.W.E, Wild, C, Walsh, M.A, von Delft, F. | Deposit date: | 2023-08-11 | Release date: | 2023-11-08 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors. Science, 382, 2023
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6HKR
| Human Cellular Retinoic Acid Binding Protein II (CRABPII) with bound synthetic retinoid DC271. | Descriptor: | 1,2-ETHANEDIOL, 4-[2-(4,4-dimethyl-1-propan-2-yl-2,3-dihydroquinolin-6-yl)ethynyl]benzoic acid, Cellular retinoic acid-binding protein 2, ... | Authors: | Tomlinson, C, Chisholm, D, Whiting, A, Pohl, E. | Deposit date: | 2018-09-07 | Release date: | 2018-11-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Novel Fluorescence Competition Assay for Retinoic Acid Binding Proteins. ACS Med Chem Lett, 9, 2018
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5OGB
| Human Cellular Retinoic Acid Binding Protein II (CRABPII) with bound synthetic retinoid DC360. | Descriptor: | 4-[2-(4,4-dimethyl-1-propan-2-yl-quinolin-6-yl)ethynyl]benzoic acid, Cellular retinoic acid-binding protein 2 | Authors: | Chisholm, D, Tomlinson, C, Whiting, A, Pohl, E. | Deposit date: | 2017-07-12 | Release date: | 2018-10-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Fluorescent Retinoic Acid Analogues as Probes for Biochemical and Intracellular Characterization of Retinoid Signaling Pathways. Acs Chem.Biol., 14, 2019
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7OXW
| CrabP2 mutant R30DK31D | Descriptor: | ACETATE ION, Cellular retinoic acid-binding protein 2, SULFATE ION | Authors: | Pastok, M.W, Basle, A, Endicott, J.A. | Deposit date: | 2021-06-23 | Release date: | 2022-07-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.16 Å) | Cite: | Structural requirements for the specific binding of CRABP2 to cyclin D3 To Be Published
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8CO8
| Structure of West Nile Virus NS2B-NS3 protease | Descriptor: | Serine protease subunit NS2B,Serine protease/Helicase NS3 | Authors: | Fairhead, M, Godoy, A.S, Koekemoer, L, Balcomb, B.H, Lithgo, R.M, Aschenbrenner, J.C, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Fearon, D, Walsh, M.A, von Delft, F. | Deposit date: | 2023-02-27 | Release date: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Structure of West Nile Virus NS2B-NS3 protease - to be published To Be Published
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8CNX
| Structure of Enterovirus D68 3C protease | Descriptor: | Protease 3C | Authors: | Lithgo, R.M, Fairhead, M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Godoy, A.S, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Fearon, D, Walsh, M.A, von Delft, F. | Deposit date: | 2023-02-24 | Release date: | 2023-04-05 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Structure of EV D68 3C protease To Be Published
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8CNY
| Structure of Enterovirus A71 3C protease | Descriptor: | Protease 3C | Authors: | Lithgo, R.M, Fairhead, M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Godoy, A.S, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Fearon, D, Walsh, M.A, von Delft, F. | Deposit date: | 2023-02-24 | Release date: | 2023-04-05 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Structure of EV D68 3C protease - to be published To Be Published
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7GAL
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z291279160 | Descriptor: | 1,2-ETHANEDIOL, 1-[2-(trifluoromethyloxy)phenyl]thiourea, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAN
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z56767614 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAB
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1255402624 | Descriptor: | 1,2-ETHANEDIOL, 2-tert-butylbenzene-1,4-diol, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAM
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z373768900 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAQ
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z755044716 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GA8
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1198158918 | Descriptor: | 1,2-ETHANEDIOL, 1H-indazole-3-carbonitrile, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAE
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1688504114 | Descriptor: | 1,2-ETHANEDIOL, 2-cyano-~{N}-(1,3,5-trimethylpyrazol-4-yl)ethanamide, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAG
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z198195770 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAO
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z57450788 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAU
| PanDDA analysis group deposition of ground-state model of MAP1LC3B | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-11 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | PanDDA analysis group deposition of ground-state model To Be Published
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7GAH
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z2033637875 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAP
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z728939702 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GA9
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1198177230 | Descriptor: | (2M)-2-(2-methoxyphenyl)-1,3,4-oxadiazole, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAR
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z820676436 | Descriptor: | 1,2-ETHANEDIOL, 2-(4-bromanylpyrazol-1-yl)-~{N}-cyclopropyl-~{N}-methyl-ethanamide, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAD
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1667545918 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAS
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z952016136 | Descriptor: | 1,2-ETHANEDIOL, 4-chloro-1H-benzimidazole, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAI
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z212122838 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated proteins 1A/1B light chain 3B, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7GAJ
| PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z285233820 | Descriptor: | (5M)-5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-amine, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Kumar, A, Marples, P.G, Tomlinson, C.W.E, Fearon, D, von-Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-08-10 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | PanDDA analysis group deposition To Be Published
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