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4PXM
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BU of 4pxm by Molmil
The Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant in Complex with Estradiol and a glucocorticoid receptor-interacting protein 1 NR box II peptide
Descriptor: ESTRADIOL, Estrogen receptor, Nuclear receptor coactivator 2
Authors:Fanning, S.W, Panchamukhi, S, Greene, G.L.
Deposit date:2014-03-24
Release date:2015-04-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.
Elife, 5, 2016
4Q50
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BU of 4q50 by Molmil
The Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant in Complex with 4-hydroxytamoxifen
Descriptor: 4-HYDROXYTAMOXIFEN, Estrogen receptor, SULFATE ION
Authors:Fanning, S.W, Greene, G.L.
Deposit date:2014-04-15
Release date:2015-04-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.
Elife, 5, 2016
8EEB
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BU of 8eeb by Molmil
Cryo-EM structure of human ABCA7 in Digitonin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Phospholipid-transporting ATPase ABCA7, ...
Authors:Alam, A, Le, L.T.M, Thompson, J.R.
Deposit date:2022-09-06
Release date:2022-12-21
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
8EE6
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BU of 8ee6 by Molmil
Cryo-EM Structure of human ABCA7 in PE/Ch nanodiscs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Phospholipid-transporting ATPase ABCA7, ...
Authors:Alam, A, Le, L.T.M, Thompson, J.R.
Deposit date:2022-09-06
Release date:2022-12-21
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
8EDW
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BU of 8edw by Molmil
Cryo-EM Structure of human ABCA7 in BPL/Ch Nanodiscs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Alam, A, Le, L.T.M, Thompson, J.R.
Deposit date:2022-09-06
Release date:2022-12-21
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
3CLL
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BU of 3cll by Molmil
Crystal structure of the Spinach Aquaporin SoPIP2;1 S115E mutant
Descriptor: Aquaporin
Authors:Nyblom, M, Alfredsson, A, Hallgren, K, Hedfalk, K, Neutze, R, Trnroth-Horsefield, S.
Deposit date:2008-03-19
Release date:2009-02-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional analysis of SoPIP2;1 mutants adds insight into plant aquaporin gating.
J.Mol.Biol., 387, 2009
3CN5
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BU of 3cn5 by Molmil
Crystal structure of the Spinach Aquaporin SoPIP2;1 S115E, S274E mutant
Descriptor: Aquaporin
Authors:Nyblom, M, Alfredsson, A, Hallgren, K, Hedfalk, K, Neutze, R, Tornroth-Horsefield, S.
Deposit date:2008-03-25
Release date:2009-02-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural and functional analysis of SoPIP2;1 mutants adds insight into plant aquaporin gating.
J.Mol.Biol., 387, 2009
8EOP
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BU of 8eop by Molmil
Cryo-EM Structure of Nanodisc reconstituted human ABCA7 EQ mutant in ATP bound closed state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Alam, A, Le, L.T.M, Thompson, J.R.
Deposit date:2022-10-04
Release date:2022-12-21
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
3CN6
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BU of 3cn6 by Molmil
Crystal structure of the Spinach Aquaporin SoPIP2;1 S274E mutant
Descriptor: Aquaporin, CADMIUM ION
Authors:Nyblom, M, Alfredsson, A, Hallgren, K, Hedfalk, K, Neutze, R, Tornroth-Horsefield, S.
Deposit date:2008-03-25
Release date:2009-02-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural and functional analysis of SoPIP2;1 mutants adds insight into plant aquaporin gating.
J.Mol.Biol., 387, 2009
7N9Z
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BU of 7n9z by Molmil
E. coli cytochrome bo3 in MSP nanodisc
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ...
Authors:Vallese, F, Clarke, O.B.
Deposit date:2021-06-19
Release date:2021-09-01
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.19 Å)
Cite:Cryo-EM structures of Escherichia coli cytochrome bo 3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site.
Proc.Natl.Acad.Sci.USA, 118, 2021
6N1G
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BU of 6n1g by Molmil
Crystal structure of Aquaglyceroporin AQP7
Descriptor: Aquaporin-7, GLYCEROL
Authors:Vahedi-Faridi, A, Lodowski, D, Kowatz, T.
Deposit date:2018-11-08
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.995 Å)
Cite:Aquaporin-7: A Dynamic Aquaglyceroporin With Greater Water and Glycerol Permeability Than Its Bacterial Homolog GlpF.
Front Physiol, 11, 2020
6MH9
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BU of 6mh9 by Molmil
The crystal structure of the Staphylococcus aureus Fatty acid Kinase (Fak) B1 protein A121I mutant to 2.02 Angstrom resolution
Descriptor: Fatty Acid Kinase (Fak) B1 protein, PALMITIC ACID
Authors:Cuypers, M.G, Ericson, M, Subramanian, C, White, S.W, Rock, C.O.
Deposit date:2018-09-17
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Identification of structural transitions in bacterial fatty acid binding proteins that permit ligand entry and exit at membranes.
J.Biol.Chem., 298, 2022
6NM1
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BU of 6nm1 by Molmil
The crystal structure of the Staphylococcus aureus Fatty acid Kinase (Fak) B1 protein A158L mutant to 2.33 Angstrom resolution exhibits a conformation change compared to the wild type form
Descriptor: Fatty acid Kinase (Fak) B1 protein, MYRISTIC ACID
Authors:Cuypers, M.G, Gullett, J.M, Subramanian, C, Ericson, M, White, S.W, Rock, C.O.
Deposit date:2019-01-10
Release date:2020-01-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Identification of structural transitions in bacterial fatty acid binding proteins that permit ligand entry and exit at membranes.
J.Biol.Chem., 298, 2022
6O3E
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BU of 6o3e by Molmil
mouse aE-catenin 82-883
Descriptor: Catenin alpha-1
Authors:Pokutta, S, Weis, W.I.
Deposit date:2019-02-26
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.001 Å)
Cite:Binding partner- and force-promoted changes in alpha E-catenin conformation probed by native cysteine labeling.
Sci Rep, 9, 2019
6O30
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BU of 6o30 by Molmil
Lipid A transporter MsbA from Salmonella typhimurium
Descriptor: Lipid A export ATP-binding/permease protein MsbA
Authors:Padayatti, P.S, Zhang, Q, Wilson, I.A, Lee, S.C, Stanfield, R.L.
Deposit date:2019-02-25
Release date:2019-06-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.47 Å)
Cite:Structural Insights into the Lipid A Transport Pathway in MsbA.
Structure, 27, 2019
6OL0
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BU of 6ol0 by Molmil
Structure of VcINDY bound to Malate
Descriptor: (2S)-2-hydroxybutanedioic acid, SODIUM ION, Transporter, ...
Authors:Sauer, D.B, Marden, J.J, Wang, D.N.
Deposit date:2019-04-15
Release date:2020-10-28
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.502 Å)
Cite:Elevator mechanism dynamics in a sodium-coupled dicarboxylate transporter
Biorxiv, 2022
6OKZ
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BU of 6okz by Molmil
Structure of VcINDY bound to Fumarate
Descriptor: FUMARIC ACID, SODIUM ION, Transporter, ...
Authors:Sauer, D.B, Marden, J, Wang, D.N.
Deposit date:2019-04-15
Release date:2020-10-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.292 Å)
Cite:Elevator mechanism dynamics in a sodium-coupled dicarboxylate transporter
Biorxiv, 2022
3SLO
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BU of 3slo by Molmil
Pre-cleavage Structure of the Autotransporter EspP - N1023D mutant
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Serine protease espP
Authors:Barnard, T.B, Noinaj, N, Easley, N.C, Kuszak, A.J, Buchanan, S.K.
Deposit date:2011-06-24
Release date:2011-11-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Molecular basis for the activation of a catalytic asparagine residue in a self-cleaving bacterial autotransporter.
J.Mol.Biol., 415, 2012
3SLT
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BU of 3slt by Molmil
Pre-cleavage Structure of the Autotransporter EspP - N1023S Mutant
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Serine protease espP
Authors:Barnard, T.B, Noinaj, N, Easley, N.C, Kuszak, A.J, Buchanan, S.K.
Deposit date:2011-06-25
Release date:2011-11-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Molecular basis for the activation of a catalytic asparagine residue in a self-cleaving bacterial autotransporter.
J.Mol.Biol., 415, 2012
3SLJ
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BU of 3slj by Molmil
Pre-cleavage Structure of the Autotransporter EspP - N1023A mutant
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Serine protease espP
Authors:Barnard, T.B, Noinaj, N, Easley, N.C, Kuszak, A.J, Buchanan, S.K.
Deposit date:2011-06-24
Release date:2011-11-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.481 Å)
Cite:Molecular basis for the activation of a catalytic asparagine residue in a self-cleaving bacterial autotransporter.
J.Mol.Biol., 415, 2012
5D6M
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BU of 5d6m by Molmil
Mn(II)-loaded MnCcP.1
Descriptor: Cytochrome c peroxidase, mitochondrial, MANGANESE (II) ION, ...
Authors:Robinson, H, Gao, Y.-G, Hosseinzadeh, P, Lu, Y.
Deposit date:2015-08-12
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.653 Å)
Cite:Enhancing Mn(II)-Binding and Manganese Peroxidase Activity in a Designed Cytochrome c Peroxidase through Fine-Tuning Secondary-Sphere Interactions.
Biochemistry, 55, 2016
8UR3
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BU of 8ur3 by Molmil
Cryo-EM reconstruction of Staphylococcus aureus Oleate hydratase (OhyA) dimer with an ordered C-terminal membrane-association domain
Descriptor: Oleate hydratase
Authors:Oldham, M.L, Qayyum, M.Z.
Deposit date:2023-10-25
Release date:2024-01-10
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:The carboxy terminus causes interfacial assembly of oleate hydratase on a membrane bilayer.
J.Biol.Chem., 300, 2024
8UR6
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BU of 8ur6 by Molmil
Cryo-EM reconstruction of Staphylococcus aureus oleate hydratase (OhyA) dimer with a disordered C-terminal membrane-association domain
Descriptor: Oleate hydratase
Authors:Oldham, M.L, Qayyum, M.Z.
Deposit date:2023-10-25
Release date:2024-01-10
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:The carboxy terminus causes interfacial assembly of oleate hydratase on a membrane bilayer.
J.Biol.Chem., 300, 2024
8UM2
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BU of 8um2 by Molmil
Carboxy terminus of Oleate Hydratase in phosphate buffer
Descriptor: Myosin-cross-reactive antigen
Authors:Grace, C.R, Radka, C.
Deposit date:2023-10-17
Release date:2024-01-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The carboxy terminus causes interfacial assembly of oleate hydratase on a membrane bilayer.
J.Biol.Chem., 300, 2024
8UM1
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BU of 8um1 by Molmil
Structure of the Carboxy terminus of Oleate Hydratase
Descriptor: Myosin-cross-reactive antigen
Authors:Grace, C.R, Radka, C.
Deposit date:2023-10-17
Release date:2024-01-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The carboxy terminus causes interfacial assembly of oleate hydratase on a membrane bilayer.
J.Biol.Chem., 300, 2024

221051

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