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6M2O
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BU of 6m2o by Molmil
Double mutant(H333A/I334A) crystal structure of benzoate coenzyme A ligase
Descriptor: Benzoate-coenzyme A ligase
Authors:Li, T.L, Adhikari, K.
Deposit date:2020-02-28
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Chemoenzymatic Synthesis and Biological Evaluation for Bioactive Molecules Derived from Bacterial Benzoyl Coenzyme A Ligase and Plant Type III Polyketide Synthase.
Biomolecules, 10, 2020
6IIX
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BU of 6iix by Molmil
The crystal structure of acyltransferase mutant, orf11*-W163A, in complex with octanoyl-CoA
Descriptor: OCTANOYL-COENZYME A, SULFATE ION, acyltransferase
Authors:Li, T.L, Huang, C.M.
Deposit date:2018-10-08
Release date:2019-10-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Teicoplanin Reprogrammed with the N-Acyl-Glucosamine Pharmacophore at the Penultimate Residue of Aglycone Acquires Broad-Spectrum Antimicrobial Activities Effectively Killing Gram-Positive and -Negative Pathogens.
Acs Infect Dis., 5, 2019
6IIY
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BU of 6iiy by Molmil
Crystal structure of deacetylase triple mutant (Orf2*T) that involving in teicoplanin biosynthetic pathway
Descriptor: COBALT (II) ION, IMIDAZOLE, deacetylase
Authors:Li, T.L, Huang, C.M.
Deposit date:2018-10-08
Release date:2019-10-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Teicoplanin Reprogrammed with the N-Acyl-Glucosamine Pharmacophore at the Penultimate Residue of Aglycone Acquires Broad-Spectrum Antimicrobial Activities Effectively Killing Gram-Positive and -Negative Pathogens.
Acs Infect Dis., 5, 2019
5XUF
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BU of 5xuf by Molmil
Crystal Structure of Transketolase in complex with hydroxylated TPP from Pichia Stipitis, crystal I
Descriptor: 2-[(2R)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2-oxidanyl-2H-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Li, T.L, Hsu, N.S, Wang, Y.L.
Deposit date:2017-06-23
Release date:2018-04-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (0.88 Å)
Cite:The Mesomeric Effect of Thiazolium on non-Kekule Diradicals in Pichia stipitis Transketolase.
Angew. Chem. Int. Ed. Engl., 57, 2018
5XQA
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BU of 5xqa by Molmil
Crystal Structure of Transketolase in complex with ribose-5-phosphate from Pichia Stipitis
Descriptor: 5-O-phosphono-alpha-D-ribofuranose, CALCIUM ION, THIAMINE DIPHOSPHATE, ...
Authors:Li, T.L, Hsu, N.S, Wang, Y.L.
Deposit date:2017-06-06
Release date:2018-06-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto-Transferring Reactions.
Chembiochem, 19, 2018
5XRV
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BU of 5xrv by Molmil
Crystal Structure of Transketolase in complex with TPP_V and fructose-6-phosphate from Pichia Stipitis
Descriptor: 2-[(5S)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methylidene-1,3-thiazolidin-5-yl]ethyl phosphono hydrogen phosphate, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Li, T.L, Hsu, N.S, Wang, Y.L.
Deposit date:2017-06-09
Release date:2018-06-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto-Transferring Reactions.
Chembiochem, 19, 2018
5XSB
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BU of 5xsb by Molmil
Crystal Structure of Transketolase in complex with TPP intermediate III from Pichia Stipitis
Descriptor: 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2H-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, CALCIUM ION, Transketolase
Authors:Li, T.L, Hsu, N.S, Wang, Y.L.
Deposit date:2017-06-13
Release date:2018-04-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (0.918 Å)
Cite:The Mesomeric Effect of Thiazolium on non-Kekule Diradicals in Pichia stipitis Transketolase.
Angew. Chem. Int. Ed. Engl., 57, 2018
5XQK
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BU of 5xqk by Molmil
Crystal Structure of Transketolase in complex with xylulose-5-phosphate from Pichia Stipitis
Descriptor: 2-C-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thia zol-3-ium-2-yl}-5-O-phosphono-D-xylitol, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Li, T.L, Hsu, N.S, Wang, Y.L.
Deposit date:2017-06-07
Release date:2018-06-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto-Transferring Reactions.
Chembiochem, 19, 2018
5XS6
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BU of 5xs6 by Molmil
Crystal Structure of Transketolase in complex with TPP Pichia Stipitis
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, THIAMINE DIPHOSPHATE, ...
Authors:Li, T.L, Hsu, N.S, Wang, Y.L.
Deposit date:2017-06-12
Release date:2018-04-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (0.972 Å)
Cite:The Mesomeric Effect of Thiazolium on non-Kekule Diradicals in Pichia stipitis Transketolase.
Angew. Chem. Int. Ed. Engl., 57, 2018
5XTL
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BU of 5xtl by Molmil
Crystal Structure of Transketolase in complex with aminopyrimidine and cysteine sulfonic acid adduct from Pichia Stipitis
Descriptor: 2-methylpyrimidin-4-amine, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Li, T.L, Hsu, N.S, Wang, Y.L.
Deposit date:2017-06-20
Release date:2018-04-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.101 Å)
Cite:The Mesomeric Effect of Thiazolium on non-Kekule Diradicals in Pichia stipitis Transketolase.
Angew. Chem. Int. Ed. Engl., 57, 2018
5XTV
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BU of 5xtv by Molmil
Crystal Structure of Transketolase in complex with TPP intermediate V from Pichia Stipitis
Descriptor: 2-[(5S)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methylidene-1,3-thiazolidin-5-yl]ethyl phosphono hydrogen phosphate, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Li, T.L, Hsu, N.S, Wang, Y.L.
Deposit date:2017-06-21
Release date:2018-04-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (0.931 Å)
Cite:The Mesomeric Effect of Thiazolium on non-Kekule Diradicals in Pichia stipitis Transketolase.
Angew. Chem. Int. Ed. Engl., 57, 2018
5XVT
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BU of 5xvt by Molmil
Crystal Structure of Transketolase in complex with hydroxylated TPP from Pichia Stipitis, crystal 2
Descriptor: 2-[(2R)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2-oxidanyl-2H-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Li, T.L, Hsu, N.S, Wang, Y.L.
Deposit date:2017-06-28
Release date:2018-04-25
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:The Mesomeric Effect of Thiazolium on non-Kekule Diradicals in Pichia stipitis Transketolase.
Angew. Chem. Int. Ed. Engl., 57, 2018
5XU9
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BU of 5xu9 by Molmil
Crystal Structure of Transketolase in complex with TPP intermediate IX and gauche form erythrose-4-phosphate from Pichia Stipitis
Descriptor: 2-[(2E)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-2-[1,2-bis(oxidanyl)ethylidene]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Li, T.L, Hsu, N.S, Wang, Y.L.
Deposit date:2017-06-22
Release date:2018-06-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.166 Å)
Cite:Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto-Transferring Reactions.
Chembiochem, 19, 2018
7V4M
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BU of 7v4m by Molmil
Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
Descriptor: 2-OXOGLUTARIC ACID, Beta-hydroxylase, FE (III) ION, ...
Authors:Li, T.L, Saeid, M.Z.
Deposit date:2021-08-13
Release date:2022-02-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7V4O
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BU of 7v4o by Molmil
Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
Descriptor: 3,6,9,12,15-PENTAOXAHEPTADECANE, Beta-hydroxylase
Authors:Li, T.L, Saeid, M.Z.
Deposit date:2021-08-13
Release date:2022-02-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7V4N
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BU of 7v4n by Molmil
Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
Descriptor: Beta-hydroxylase, FE (III) ION
Authors:Li, T.L, Saeid, M.Z.
Deposit date:2021-08-13
Release date:2022-02-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7V4P
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BU of 7v4p by Molmil
Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
Descriptor: Beta-hydroxylase, FE (III) ION
Authors:Li, T.L, Saeid, M.Z.
Deposit date:2021-08-13
Release date:2022-02-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7EU6
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BU of 7eu6 by Molmil
Structural and mechanistic studies of a novel non-heme iron epimerase/lyase and its utilization in chemoselective synthesis.
Descriptor: Cupin domain-containing protein, FE (III) ION, PHOSPHITE ION
Authors:Li, T.L, Li, Y.S, Chen, M.H.
Deposit date:2021-05-16
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.050108 Å)
Cite:Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions.
Acs Catalysis, 12, 2022
7EUZ
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BU of 7euz by Molmil
Structural and mechanistic studies of a novel non-heme iron epimerase/lyase and its utilization in chemoselective synthesis.
Descriptor: (2S,3R)-2-azanyl-3-(1H-indol-3-yl)butanoic acid, Cupin domain-containing protein, FE (III) ION, ...
Authors:Li, T.L, Li, Y.S, Chen, M.H.
Deposit date:2021-05-19
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.91028166 Å)
Cite:Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions.
Acs Catalysis, 12, 2022
7EUE
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BU of 7eue by Molmil
Structural and mechanistic studies of a novel non-heme iron epimerase/lyase and its utilization in chemoselective synthesis.
Descriptor: 3-(1H-INDOL-3-YL)-2-OXOPROPANOIC ACID, Cupin domain-containing protein, FE (III) ION
Authors:Li, T.L, Li, Y.S, Chen, M.H.
Deposit date:2021-05-17
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.08757067 Å)
Cite:Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions.
Acs Catalysis, 12, 2022
7F6X
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BU of 7f6x by Molmil
Structural and mechanistic studies of a novel non-heme iron epimerase/lyase and its utilization in chemoselective synthesis.
Descriptor: 1H-INDOLE-3-CARBALDEHYDE, Cupin domain-containing protein, FE (III) ION, ...
Authors:Li, T.L, Li, Y.S, Chen, M.H.
Deposit date:2021-06-26
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structural and Mechanistic Bases for StnK3 and Its Mutant-MediatedLewis-Acid-Dependent Epimerization and Retro-Aldol Reactions.
Acs Catalysis, 12, 2022
7EQK
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BU of 7eqk by Molmil
Structural and mechanistic studies of a novel non-heme iron epimerase/lyase and its utilization in chemoselective synthesis.
Descriptor: (E)-3-(1H-indol-3-yl)-2-oxidanyl-but-2-enoic acid, 1-(1~{H}-indol-3-yl)ethanone, Cupin domain-containing protein, ...
Authors:Li, T.L, Li, Y.S, Chen, M.H.
Deposit date:2021-05-03
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.04001021 Å)
Cite:Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions.
Acs Catalysis, 12, 2022
7EUP
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BU of 7eup by Molmil
Structural and mechanistic studies of a novel non-heme iron epimerase/lyase and its utilization in chemoselective synthesis.
Descriptor: (2S,3R)-2-azanyl-3-phenyl-butanoic acid, Cupin domain-containing protein, FE (III) ION
Authors:Li, T.L, Li, Y.S, Chen, M.H.
Deposit date:2021-05-18
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.11043429 Å)
Cite:Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions.
Acs Catalysis, 12, 2022
7V4F
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BU of 7v4f by Molmil
Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
Descriptor: (2S,3S)-2-azanyl-4-(2-hydroxy-2-oxoethylamino)-3-oxidanyl-butanoic acid, Beta-hydroxylase, CARBON DIOXIDE, ...
Authors:Li, T.L, Saeid, M.Z.
Deposit date:2021-08-13
Release date:2022-02-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7F0A
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BU of 7f0a by Molmil
Crystal structure of capreomycin phosphotransferase
Descriptor: Capreomycin phosphotransferase
Authors:Chang, C.Y, Pan, Y.C, Wang, Y.L, Toh, S.I.
Deposit date:2021-06-03
Release date:2022-05-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Dual-Mechanism Confers Self-Resistance to the Antituberculosis Antibiotic Capreomycin.
Acs Chem.Biol., 17, 2022

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