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1U3W
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BU of 1u3w by Molmil
Crystal Structure of Human Alcohol Dehydrogenase Gamma-2-Gamma-2 Isoform Complexed with N-1-Methylheptylformamide Determined to 1.45 Angstrom Resolution
Descriptor: 1-METHYLHEPTYLFORMAMIDE, Alcohol dehydrogenase gamma chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Gibbons, B.J, Hurley, T.D.
Deposit date:2004-07-23
Release date:2004-10-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of three class I human alcohol dehydrogenases complexed with isoenzyme specific formamide inhibitors
Biochemistry, 43, 2004
1U3T
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BU of 1u3t by Molmil
Crystal Structure of Human Alcohol Dehydrogenase Alpha-Alpha Isoform Complexed with N-Cyclopentyl-N-Cyclobutylformamide Determined to 2.5 Angstrom Resolution
Descriptor: Alcohol dehydrogenase alpha chain, CYCLOBUTYL(CYCLOPENTYL)FORMAMIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Gibbons, B.J, Hurley, T.D.
Deposit date:2004-07-23
Release date:2004-10-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structure of three class I human alcohol dehydrogenases complexed with isoenzyme specific formamide inhibitors
Biochemistry, 43, 2004
3O3C
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BU of 3o3c by Molmil
Glycogen synthase basal state UDP complex
Descriptor: Glycogen [starch] synthase isoform 2, SULFATE ION, URIDINE-5'-DIPHOSPHATE
Authors:Baskaran, S, Hurley, T.D.
Deposit date:2010-07-23
Release date:2010-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.512 Å)
Cite:Structural basis for glucose-6-phosphate activation of glycogen synthase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3NCH
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BU of 3nch by Molmil
Yeast Glycogen Synthase (Gsy2p) Basal State Conformation
Descriptor: Glycogen [starch] synthase isoform 2, SULFATE ION
Authors:Baskaran, S, Hurley, T.D.
Deposit date:2010-06-04
Release date:2010-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Structural basis for glucose-6-phosphate activation of glycogen synthase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3NAZ
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BU of 3naz by Molmil
Basal state form of Yeast Glycogen Synthase
Descriptor: Glycogen [starch] synthase isoform 2, PEPTIDE, SULFATE ION
Authors:Baskaran, S, Hurley, T.D.
Deposit date:2010-06-02
Release date:2010-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for glucose-6-phosphate activation of glycogen synthase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3RSZ
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BU of 3rsz by Molmil
Maltodextran bound basal state conformation of yeast glycogen synthase isoform 2
Descriptor: Glycogen [starch] synthase isoform 2, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Baskaran, S, Hurley, T.D.
Deposit date:2011-05-02
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.009 Å)
Cite:Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen.
J.Biol.Chem., 286, 2011
3RT1
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Maltodextarn bound activated state form of yeast glycogen synthase isoform 2
Descriptor: 6-O-phosphono-alpha-D-glucopyranose, DI(HYDROXYETHYL)ETHER, PROTEIN (Glycogen [starch] synthase isoform 2), ...
Authors:Baskaran, S, Hurley, T.D.
Deposit date:2011-05-02
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen.
J.Biol.Chem., 286, 2011
4KQ2
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BU of 4kq2 by Molmil
Glucose1,2cyclic phosphate bound activated state of Yeast Glycogen Synthase
Descriptor: (2R,3aR,5R,6S,7S,7aR)-5-(hydroxymethyl)tetrahydro-3aH-[1,3,2]dioxaphospholo[4,5-b]pyran-2,6,7-triol 2-oxide, 6-O-phosphono-alpha-D-glucopyranose, BARIUM ION, ...
Authors:Chikwana, V.M, Hurley, T.D.
Deposit date:2013-05-14
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural basis for 2'-phosphate incorporation into glycogen by glycogen synthase.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KQM
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BU of 4kqm by Molmil
Crystal structure of yeast glycogen synthase E169Q mutant in complex with glucose and UDP
Descriptor: 6-O-phosphono-alpha-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Gsy2p, ...
Authors:Chikwana, V.M, Hurley, T.D.
Deposit date:2013-05-15
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Structural basis for 2'-phosphate incorporation into glycogen by glycogen synthase.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KQ1
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BU of 4kq1 by Molmil
Crystal structure of yeast glycogen synthase in complex with uridine-5'-monophosphate
Descriptor: 6-O-phosphono-alpha-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Gsy2p, ...
Authors:Chikwana, V.M, Hurley, T.D.
Deposit date:2013-05-14
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Structural basis for 2'-phosphate incorporation into glycogen by glycogen synthase.
Proc.Natl.Acad.Sci.USA, 110, 2013
1A4Z
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BU of 1a4z by Molmil
ALDEHYDE DEHYDROGENASE FROM BOVINE MITOCHONDRIA COMPLEX WITH NAD (REDUCED) AND SAMARIUM (III)
Descriptor: ALDEHYDE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SAMARIUM (III) ION
Authors:Steinmetz, C.G, Hurley, T.D.
Deposit date:1998-02-10
Release date:1998-04-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of mitochondrial aldehyde dehydrogenase: the genetic component of ethanol aversion.
Structure, 5, 1997
1AG8
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BU of 1ag8 by Molmil
ALDEHYDE DEHYDROGENASE FROM BOVINE MITOCHONDRIA
Descriptor: ALDEHYDE DEHYDROGENASE
Authors:Steinmetz, C.G, Hurley, T.D.
Deposit date:1997-04-03
Release date:1997-10-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of mitochondrial aldehyde dehydrogenase: the genetic component of ethanol aversion.
Structure, 5, 1997
1M6W
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BU of 1m6w by Molmil
Binary complex of Human glutathione-dependent formaldehyde dehydrogenase and 12-Hydroxydodecanoic acid
Descriptor: 12-HYDROXYDODECANOIC ACID, Glutathione-dependent formaldehyde dehydrogenase, PHOSPHATE ION, ...
Authors:Sanghani, P.C, Robinson, H, Bosron, W.F, Hurley, T.D.
Deposit date:2002-07-17
Release date:2002-07-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Human glutathione-dependent formaldehyde dehydrogenase. Structures of apo, binary, and inhibitory ternary complexes.
Biochemistry, 41, 2002
1MC5
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BU of 1mc5 by Molmil
Ternary complex of Human glutathione-dependent formaldehyde dehydrogenase with S-(hydroxymethyl)glutathione and NADH
Descriptor: 2-AMINO-4-[1-CARBOXYMETHYL-CARBAMOYL)-2-HYDROXYMETHYLSULFANYL-ETHYLCARBAMOYL]-BUTYRIC ACID, Alcohol dehydrogenase class III chi chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Sanghani, P.C, Bosron, W.F, Hurley, T.D.
Deposit date:2002-08-05
Release date:2003-03-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human glutathione-dependent formaldehyde dehydrogenase. Structural changes associated with Ternary Complex formation
Biochemistry, 41, 2002
1MP0
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BU of 1mp0 by Molmil
Binary Complex of Human Glutathione-Dependent Formaldehyde Dehydrogenase with NAD(H)
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Sanghani, P.C, Robinson, H, Hurley, T.D, Bosron, W.F.
Deposit date:2002-09-10
Release date:2002-09-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-function relationships in human Class III alcohol dehydrogenase (formaldehyde dehydrogenase)
Chem.Biol.Interact., 143, 2003
1LL3
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BU of 1ll3 by Molmil
Crystal Structure of Rabbit Muscle Glycogenin
Descriptor: GLYCEROL, GLYCOGENIN-1
Authors:Gibbons, B.J, Roach, P.J, Hurley, T.D.
Deposit date:2002-04-26
Release date:2002-05-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the autocatalytic initiator of glycogen biosynthesis, glycogenin.
J.Mol.Biol., 319, 2002
1LL2
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BU of 1ll2 by Molmil
Crystal Structure of Rabbit Muscle Glycogenin Complexed with UDP-glucose and Manganese
Descriptor: GLYCOGENIN-1, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Gibbons, B.J, Roach, P.J, Hurley, T.D.
Deposit date:2002-04-26
Release date:2002-05-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the autocatalytic initiator of glycogen biosynthesis, glycogenin.
J.Mol.Biol., 319, 2002
1M6H
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BU of 1m6h by Molmil
Human glutathione-dependent formaldehyde dehydrogenase
Descriptor: Glutathione-dependent formaldehyde dehydrogenase, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Sanghani, P.C, Robinson, H, Bosron, W.F, Hurley, T.D.
Deposit date:2002-07-16
Release date:2002-07-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human glutathione-dependent formaldehyde dehydrogenase. Structures of apo, binary, and inhibitory ternary complexes.
Biochemistry, 41, 2002
1MA0
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BU of 1ma0 by Molmil
Ternary complex of Human glutathione-dependent formaldehyde dehydrogenase with NAD+ and dodecanoic acid
Descriptor: Glutathione-dependent formaldehyde dehydrogenase, LAURIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Sanghani, P.C, Robinson, H, Bosron, W.F, Hurley, T.D.
Deposit date:2002-07-30
Release date:2002-08-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Human glutathione-dependent formaldehyde dehydrogenase. Structures of apo, binary, and inhibitory ternary complexes.
Biochemistry, 41, 2002
1LL0
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BU of 1ll0 by Molmil
Crystal Structure of Rabbit Muscle Glycogenin
Descriptor: GLYCOGENIN-1
Authors:Gibbons, B.J, Roach, P.J, Hurley, T.D.
Deposit date:2002-04-26
Release date:2002-05-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.43 Å)
Cite:Crystal structure of the autocatalytic initiator of glycogen biosynthesis, glycogenin.
J.Mol.Biol., 319, 2002
2PS1
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BU of 2ps1 by Molmil
S. cerevisiae orotate phosphoribosyltransferase complexed with orotic acid and PRPP
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, OROTIC ACID, ...
Authors:Gonzalez-Segura, L, Hurley, T.D, McClard, R.W.
Deposit date:2007-05-04
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Ternary complex formation and induced asymmetry in orotate phosphoribosyltransferase.
Biochemistry, 46, 2007
1HSO
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BU of 1hso by Molmil
HUMAN ALPHA ALCOHOL DEHYDROGENASE (ADH1A)
Descriptor: 4-IODOPYRAZOLE, CLASS I ALCOHOL DEHYDROGENASE 1, ALPHA SUBUNIT, ...
Authors:Niederhut, M.S, Gibbons, B.J, Perez-Miller, S, Hurley, T.D.
Deposit date:2000-12-27
Release date:2001-01-10
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structures of the three human class I alcohol dehydrogenases.
Protein Sci., 10, 2001
1HT0
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BU of 1ht0 by Molmil
HUMAN GAMMA-2 ALCOHOL DEHYDROGENSE
Descriptor: CLASS I ALCOHOL DEHYDROGENASE 3, GAMMA SUBUNIT, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Niederhut, M.S, Gibbons, B.J, Perez-Miller, S, Hurley, T.D.
Deposit date:2000-12-27
Release date:2001-01-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structures of the three human class I alcohol dehydrogenases.
Protein Sci., 10, 2001
1HSZ
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BU of 1hsz by Molmil
HUMAN BETA-1 ALCOHOL DEHYDROGENASE (ADH1B*1)
Descriptor: CLASS I ALCOHOL DEHYDROGENASE 1, BETA SUBUNIT, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Niederhut, M.S, Gibbons, B.J, Perez-Miller, S, Hurley, T.D.
Deposit date:2000-12-27
Release date:2001-01-10
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three-dimensional structures of the three human class I alcohol dehydrogenases.
Protein Sci., 10, 2001
2ONO
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BU of 2ono by Molmil
Arg475Gln Mutant of Mitochondrial Aldehyde Dehydrogenase, apo form, pseudo-merohedrally twinned
Descriptor: Aldehyde dehydrogenase
Authors:Larson, H.N, Hurley, T.D.
Deposit date:2007-01-24
Release date:2007-03-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487.
J.Biol.Chem., 282, 2007

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