5GT8
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![BU of 5gt8 by Molmil](/molmil-images/mine/5gt8) | Crystal Structure of apo-CASTOR1 | Descriptor: | GATS-like protein 3 | Authors: | Guo, L, Deng, D. | Deposit date: | 2016-08-18 | Release date: | 2017-08-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structures of arginine sensor CASTOR1 in arginine-bound and ligand free states Biochem. Biophys. Res. Commun., 508, 2019
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3FUP
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![BU of 3fup by Molmil](/molmil-images/mine/3fup) | Crystal structures of JAK1 and JAK2 inhibitor complexes | Descriptor: | 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile, Tyrosine-protein kinase JAK2 | Authors: | Williams, N.K, Bamert, R.S, Patel, O, Fantino, E, Rossjohn, J, Lucet, I.S. | Deposit date: | 2009-01-14 | Release date: | 2009-02-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains. J.Mol.Biol., 387, 2009
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5ZGE
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![BU of 5zge by Molmil](/molmil-images/mine/5zge) | Crystal structure of NDM-1 at pH5.5 (Bis-Tris) in complex with hydrolyzed ampicillin | Descriptor: | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, HYDROXIDE ION, Metallo-beta-lactamase type 2, ... | Authors: | Zhang, H, Hao, Q. | Deposit date: | 2018-03-08 | Release date: | 2018-08-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
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5ZGR
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![BU of 5zgr by Molmil](/molmil-images/mine/5zgr) | Crystal structure of NDM-1 at pH7.3 (HEPES) in complex with hydrolyzed ampicillin | Descriptor: | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, GLYCEROL, Metallo-beta-lactamase type 2, ... | Authors: | Zhang, H, Hao, Q. | Deposit date: | 2018-03-10 | Release date: | 2018-08-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
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5ZGV
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![BU of 5zgv by Molmil](/molmil-images/mine/5zgv) | |
5GT7
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![BU of 5gt7 by Molmil](/molmil-images/mine/5gt7) | Crystal Structure of Arg-bound CASTOR1 | Descriptor: | ARGININE, GATS-like protein 3, MALONATE ION | Authors: | Guo, L, Deng, D. | Deposit date: | 2016-08-18 | Release date: | 2017-08-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.048 Å) | Cite: | Crystal structures of arginine sensor CASTOR1 in arginine-bound and ligand free states Biochem. Biophys. Res. Commun., 508, 2019
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4NA7
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![BU of 4na7 by Molmil](/molmil-images/mine/4na7) | Factor XIA in complex with the inhibitor 3'-[(2S,4R)-6-carbamimidoyl-4-methyl-4-phenyl-1,2,3,4-tetrahydroquinolin-2-yl]-4-carbamoyl-5'-[(3-methylbutanoyl)amino]biphenyl-2-carboxylic acid | Descriptor: | 3'-[(2S,4R)-6-carbamimidoyl-4-methyl-4-phenyl-1,2,3,4-tetrahydroquinolin-2-yl]-4-carbamoyl-5'-[(3-methylbutanoyl)amino]biphenyl-2-carboxylic acid, Coagulation factor XI, SULFATE ION | Authors: | Wei, A. | Deposit date: | 2013-10-21 | Release date: | 2014-02-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Tetrahydroquinoline Derivatives as Potent and Selective Factor XIa Inhibitors. J.Med.Chem., 57, 2014
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5ZGY
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![BU of 5zgy by Molmil](/molmil-images/mine/5zgy) | |
5ZGW
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![BU of 5zgw by Molmil](/molmil-images/mine/5zgw) | |
5ZGT
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![BU of 5zgt by Molmil](/molmil-images/mine/5zgt) | |
5ZH1
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![BU of 5zh1 by Molmil](/molmil-images/mine/5zh1) | |
5ZGQ
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![BU of 5zgq by Molmil](/molmil-images/mine/5zgq) | Crystal structure of NDM-1 at pH7.5 (Tris-HCl, (NH4)2SO4) in complex with hydrolyzed ampicillin | Descriptor: | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, HYDROXIDE ION, Metallo-beta-lactamase type 2, ... | Authors: | Zhang, H, Hao, Q. | Deposit date: | 2018-03-10 | Release date: | 2018-08-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
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5ZGZ
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![BU of 5zgz by Molmil](/molmil-images/mine/5zgz) | |
7E7E
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![BU of 7e7e by Molmil](/molmil-images/mine/7e7e) | The co-crystal structure of ACE2 with Fab | Descriptor: | Processed angiotensin-converting enzyme 2, ZINC ION, h11B11-Fab | Authors: | Xiao, J.Y, Zhang, Y. | Deposit date: | 2021-02-26 | Release date: | 2021-07-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | A broadly neutralizing humanized ACE2-targeting antibody against SARS-CoV-2 variants. Nat Commun, 12, 2021
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5ZGF
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![BU of 5zgf by Molmil](/molmil-images/mine/5zgf) | Crystal structure of NDM-1 Q123G mutant | Descriptor: | HYDROXIDE ION, Metallo-beta-lactamase type 2, ZINC ION | Authors: | Zhang, H, Hao, Q. | Deposit date: | 2018-03-08 | Release date: | 2018-08-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
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5ZGI
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![BU of 5zgi by Molmil](/molmil-images/mine/5zgi) | |
5ZGX
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![BU of 5zgx by Molmil](/molmil-images/mine/5zgx) | |
4NA8
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![BU of 4na8 by Molmil](/molmil-images/mine/4na8) | Factor XIa in complex with the inhibitor 5-aminocarbonyl-2-[3-[(2s,4r)-6-carbamimidoyl-4-methyl-4-phenyl-2,3-dihydro-1h-quinolin-2-yl]phenyl]benzoic acid | Descriptor: | 1,2-ETHANEDIOL, 5-aminocarbonyl-2-[3-[(2S,4R)-6-carbamimidoyl-4-methyl-4-phenyl-2,3-dihydro-1H-quinolin-2-yl]phenyl]benzoic acid, Coagulation factor XI, ... | Authors: | Wei, A. | Deposit date: | 2013-10-21 | Release date: | 2014-02-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Tetrahydroquinoline Derivatives as Potent and Selective Factor XIa Inhibitors. J.Med.Chem., 57, 2014
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3H7V
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![BU of 3h7v by Molmil](/molmil-images/mine/3h7v) | CRYSTAL STRUCTURE OF O-SUCCINYLBENZOATE SYNTHASE FROM THERMOSYNECHOCOCCUS ELONGATUS BP-1 complexed with MG in the active site | Descriptor: | MAGNESIUM ION, O-SUCCINYLBENZOATE SYNTHASE | Authors: | Fedorov, A.A, Fedorov, E.V, Sauder, J.M, Burley, S.K, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-04-28 | Release date: | 2009-05-12 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family. Proc.Natl.Acad.Sci.USA, 111, 2014
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3H70
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![BU of 3h70 by Molmil](/molmil-images/mine/3h70) | Crystal structure of o-succinylbenzoic acid synthetase from staphylococcus aureus Complexed with mg in the active site | Descriptor: | MAGNESIUM ION, O-succinylbenzoic acid (OSB) synthetase | Authors: | Fedorov, A.A, Fedorov, E.V, Sauder, J.M, Burley, S.K, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-04-24 | Release date: | 2009-05-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family. Proc.Natl.Acad.Sci.USA, 111, 2014
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8GCQ
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![BU of 8gcq by Molmil](/molmil-images/mine/8gcq) | SFX structure of oxidized cytochrome c oxidase at 2.38 Angstrom resolution | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | Authors: | Ishigami, I, Yeh, S.-R, Rousseau, D.L. | Deposit date: | 2023-03-02 | Release date: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Structural insights into functional properties of the oxidized form of cytochrome c oxidase. Nat Commun, 14, 2023
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7YKF
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![BU of 7ykf by Molmil](/molmil-images/mine/7ykf) | Crystal structure of MAGI2 PDZ0-GK/pEphexin4 complex | Descriptor: | Ephexin4, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 | Authors: | Zhang, M, Lin, L, Zhu, J. | Deposit date: | 2022-07-22 | Release date: | 2023-08-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
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7YKI
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![BU of 7yki by Molmil](/molmil-images/mine/7yki) | Crystal structure of MAGI2 PDZ0-GK domain in complex with phospho-SAPAP1 GBR3 peptide | Descriptor: | GLYCEROL, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ... | Authors: | Zhang, M, Lin, L, Zhu, J. | Deposit date: | 2022-07-22 | Release date: | 2023-08-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
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7YKG
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![BU of 7ykg by Molmil](/molmil-images/mine/7ykg) | Crystal structure of MAGI2 PDZ0-GK/pSGEF complex | Descriptor: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, SGEF | Authors: | Zhang, M, Lin, L, Zhu, J. | Deposit date: | 2022-07-22 | Release date: | 2023-08-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
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7YKH
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![BU of 7ykh by Molmil](/molmil-images/mine/7ykh) | Crystal structure of MAGI2 PDZ0-GK domain in complex with phospho-SAPAP1 GBR2 peptide | Descriptor: | GLYCEROL, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ... | Authors: | Zhang, M, Lin, L, Zhu, J. | Deposit date: | 2022-07-22 | Release date: | 2023-08-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
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