6PWP
 
 | | MscS Nanodisc | | Descriptor: | Small-conductance mechanosensitive channel | | Authors: | Reddy, B.G, Perozo, E. | | Deposit date: | 2019-07-23 | | Release date: | 2020-01-08 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Molecular basis of force-from-lipids gating in the mechanosensitive channel MscS.
Elife, 8, 2019
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6ON9
 | | Crystal Structure of the ZIG-8-RIG-5 IG1-IG1 heterodimer, tetragonal form | | Descriptor: | NeuRonal IgCAM-5, SODIUM ION, SULFATE ION, ... | | Authors: | Cheng, S, Kurleto, J.D, Ozkan, E. | | Deposit date: | 2019-04-20 | | Release date: | 2019-05-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.995 Å) | | Cite: | Family of neural wiring receptors in bilaterians defined by phylogenetic, biochemical, and structural evidence.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6ONB
 | | Crystal Structure of the ZIG-8-RIG-5 IG1-IG1 heterodimer, monoclinic form | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NeuRonal IgCAM-5, ... | | Authors: | Cheng, S, Kurleto, J.D, Ozkan, E. | | Deposit date: | 2019-04-20 | | Release date: | 2019-05-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.696 Å) | | Cite: | Family of neural wiring receptors in bilaterians defined by phylogenetic, biochemical, and structural evidence.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6ON6
 | | Crystal Structure of the RIG-5 IG1 homodimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, NeuRonal IgCAM-5 | | Authors: | Cheng, S, Kurleto, J.D, Ozkan, E. | | Deposit date: | 2019-04-20 | | Release date: | 2019-05-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.423 Å) | | Cite: | Family of neural wiring receptors in bilaterians defined by phylogenetic, biochemical, and structural evidence.
Proc.Natl.Acad.Sci.USA, 116, 2019
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7LTW
 | | Crystal structure of the mouse Kirrel2 D1 homodimer | | Descriptor: | Kin of IRRE-like protein 2, SODIUM ION | | Authors: | Roman, C.A, Pak, J.S, Wang, J, Ozkan, E. | | Deposit date: | 2021-02-20 | | Release date: | 2021-11-24 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors.
Cell Rep, 37, 2021
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7LU6
 | | Crystal structure of the mouse Kirrel3 D1 homodimer | | Descriptor: | Kin of IRRE-like protein 3, SODIUM ION | | Authors: | Roman, C.A, Pak, J.S, Wang, J, Ozkan, E. | | Deposit date: | 2021-02-21 | | Release date: | 2021-11-24 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors.
Cell Rep, 37, 2021
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5YPC
 | | p62/SQSTM1 ZZ domain with Phe-peptide | | Descriptor: | 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION | | Authors: | Kwon, D.H, Kim, L, Song, H.K. | | Deposit date: | 2017-11-01 | | Release date: | 2018-08-29 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.962 Å) | | Cite: | Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
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5YPB
 | | p62/SQSTM1 ZZ domain with His-peptide | | Descriptor: | 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION | | Authors: | Kwon, D.H, Kim, L, Song, H.K. | | Deposit date: | 2017-11-01 | | Release date: | 2018-08-29 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
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5YPH
 | | p62/SQSTM1 ZZ domain with Ile-peptide | | Descriptor: | 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION | | Authors: | Kwon, D.H, Kim, L, Song, H.K. | | Deposit date: | 2017-11-01 | | Release date: | 2018-08-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.629 Å) | | Cite: | Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
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5YP8
 | | p62/SQSTM1 ZZ domain with Arg-peptide | | Descriptor: | 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION | | Authors: | Kwon, D.H, Kim, L, Song, H.K. | | Deposit date: | 2017-11-01 | | Release date: | 2018-08-29 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.448 Å) | | Cite: | Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
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5YPG
 | | p62/SQSTM1 ZZ domain with Leu-peptide | | Descriptor: | 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION | | Authors: | Kwon, D.H, Kim, L, Song, H.K. | | Deposit date: | 2017-11-01 | | Release date: | 2018-08-29 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.199 Å) | | Cite: | Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
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5YPF
 | | p62/SQSTM1 ZZ domain with Trp-peptide | | Descriptor: | 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION | | Authors: | Kwon, D.H, Kim, L, Song, H.K. | | Deposit date: | 2017-11-01 | | Release date: | 2018-08-29 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.951 Å) | | Cite: | Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
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5YPE
 | | p62/SQSTM1 ZZ domain with Tyr-peptide | | Descriptor: | 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION | | Authors: | Kwon, D.H, Kim, L, Song, H.K. | | Deposit date: | 2017-11-01 | | Release date: | 2018-08-29 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.851 Å) | | Cite: | Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
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5YP7
 | | p62/SQSTM1 ZZ domain | | Descriptor: | Sequestosome-1, ZINC ION | | Authors: | Kwon, D.H, Kim, L, Song, H.K. | | Deposit date: | 2017-11-01 | | Release date: | 2018-08-29 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.424 Å) | | Cite: | Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
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5YPA
 | | p62/SQSTM1 ZZ domain with Lys-peptide | | Descriptor: | 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION | | Authors: | Kwon, D.H, Kim, L, Song, H.K. | | Deposit date: | 2017-11-01 | | Release date: | 2018-08-29 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
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2MUK
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5UJ2
 | | Crystal structure of HCV NS5B genotype 2A JFH-1 isolate with S15G E86Q E87Q C223H V321I mutations and Delta8 neta hairpoin loop deletion in complex with GS-639476 (diphsohate version of GS-9813), Mn2+ and symmetrical primer template 5'-AUAAAUUU | | Descriptor: | (1S)-1-(4-aminoimidazo[2,1-f][1,2,4]triazin-7-yl)-1,4-anhydro-2-deoxy-2-fluoro-5-O-[(S)-hydroxy(phosphonooxy)phosphoryl]-2-methyl-D-ribitol, CHLORIDE ION, Genome polyprotein, ... | | Authors: | Edwards, T.E, Fox III, D, Appleby, T.C, Murakami, E, Rey, A, McGrath, M.E. | | Deposit date: | 2017-01-16 | | Release date: | 2017-03-22 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Discovery of a 2'-fluoro-2'-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties.
Bioorg. Med. Chem. Lett., 27, 2017
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7EPP
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