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4RD3
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BU of 4rd3 by Molmil
Structure of aIF2-gamma H97A variant from Sulfolobus solfataricus bound to GDP and Pi
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E.
Deposit date:2014-09-18
Release date:2015-05-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2.
Nucleic Acids Res., 43, 2015
6EZ3
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BU of 6ez3 by Molmil
Structure of CDPS from Staphylococcus haemolyticus
Descriptor: Cyclo(L-leucyl-L-leucyl) synthase, SULFATE ION
Authors:Schmitt, E, Mechulam, Y, Bourgeois, G.
Deposit date:2017-11-14
Release date:2018-11-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for partition of the cyclodipeptide synthases into two subfamilies.
J. Struct. Biol., 203, 2018
6FQ2
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BU of 6fq2 by Molmil
Structure of minimal sequence for left -handed G-quadruplex formation
Descriptor: DNA (5'-D(*GP*TP*GP*GP*TP*GP*GP*TP*GP*GP*TP*G)-3'), POTASSIUM ION
Authors:Schmitt, E, Mechulam, Y, Phan, A.T, Heddi, B, Bakalar, B.
Deposit date:2018-02-13
Release date:2018-12-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:A Minimal Sequence for Left-Handed G-Quadruplex Formation.
Angew. Chem. Int. Ed. Engl., 58, 2019
2MS9
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BU of 2ms9 by Molmil
Solution structure of a G-quadruplex
Descriptor: DNA (28-MER)
Authors:Chung, W.J, Heddi, B, Schmitt, E, Lim, K.W, Mechulam, Y, Phan, A.T.
Deposit date:2014-07-25
Release date:2015-02-18
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of a left-handed DNA G-quadruplex
Proc.Natl.Acad.Sci.USA, 2015
1P7P
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BU of 1p7p by Molmil
Methionyl-tRNA synthetase from Escherichia coli complexed with methionine phosphonate
Descriptor: (1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHONIC ACID, Methionyl-tRNA synthetase, ZINC ION
Authors:Crepin, T, Schmitt, E, Mechulam, Y, Sampson, P.B, Vaughan, M.D, Honek, J.F, Blanquet, S.
Deposit date:2003-05-05
Release date:2004-02-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.
J.Mol.Biol., 332, 2003
1PFY
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BU of 1pfy by Molmil
METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH METHIONYL SULPHAMOYL ADENOSINE
Descriptor: 5'-O-[(L-METHIONYL)-SULPHAMOYL]ADENOSINE, Methionyl-tRNA synthetase, ZINC ION
Authors:Crepin, T, Schmitt, E, Mechulam, Y, Sampson, P.B, Vaughan, M.D, Honek, J.F, Blanquet, S.
Deposit date:2003-05-27
Release date:2004-02-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.
J.Mol.Biol., 332, 2003
1PFU
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BU of 1pfu by Molmil
METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH METHIONINE PHOSPHINATE
Descriptor: (1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC ACID, Methionyl-tRNA synthetase, ZINC ION
Authors:Crepin, T, Schmitt, E, Mechulam, Y, Sampson, P.B, Vaughan, M.D, Honek, J.F, Blanquet, S.
Deposit date:2003-05-27
Release date:2004-02-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.
J.Mol.Biol., 332, 2003
1PG0
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BU of 1pg0 by Molmil
Methionyl-trna synthetase from escherichia coli complexed with methioninyl adenylate
Descriptor: L-METHIONYL ADENYLATE, Methionyl-tRNA synthetase
Authors:Crepin, T, Schmitt, E, Mechulam, Y, Sampson, P.B, Vaughan, M.D, Honek, J.F, Blanquet, S.
Deposit date:2003-05-27
Release date:2004-02-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.
J.Mol.Biol., 332, 2003
1PFW
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BU of 1pfw by Molmil
METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH TRIFLUOROMETHIONINE
Descriptor: 2-AMINO-4-TRIFLUOROMETHYLSULFANYL-BUTYRIC ACID, Methionyl-tRNA synthetase, ZINC ION
Authors:Crepin, T, Schmitt, E, Mechulam, Y, Sampson, P.B, Vaughan, M.D, Honek, J.F, Blanquet, S.
Deposit date:2003-05-27
Release date:2004-02-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.
J.Mol.Biol., 332, 2003
1PFV
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BU of 1pfv by Molmil
METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH DIFLUOROMETHIONINE
Descriptor: Methionyl-tRNA synthetase, S-(DIFLUOROMETHYL)HOMOCYSTEINE, ZINC ION
Authors:Crepin, T, Schmitt, E, Mechulam, Y, Sampson, P.B, Vaughan, M.D, Honek, J.F, Blanquet, S.
Deposit date:2003-05-27
Release date:2004-02-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.
J.Mol.Biol., 332, 2003
1PG2
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BU of 1pg2 by Molmil
METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH METHIONINE AND ADENOSINE
Descriptor: ADENOSINE, METHIONINE, Methionyl-tRNA synthetase
Authors:Crepin, T, Schmitt, E, Mechulam, Y, Sampson, P.B, Vaughan, M.D, Honek, J.F, Blanquet, S.
Deposit date:2003-05-27
Release date:2004-02-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.
J.Mol.Biol., 332, 2003
1MKH
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BU of 1mkh by Molmil
C-terminal domain of methionyl-tRNA synthetase from Pyrococcus abyssi
Descriptor: C-terminal domain of Methionyl-tRNA synthetase
Authors:Crepin, T, Schmitt, E, Blanquet, S, Mechulam, Y.
Deposit date:2002-08-29
Release date:2003-02-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structure and function of the C-terminal domain of methionyl-tRNA synthetase
Biochemistry, 41, 2002
6GZ6
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BU of 6gz6 by Molmil
Structure of a left-handed G-quadruplex
Descriptor: DNA (27-MER), POTASSIUM ION
Authors:Bakalar, B, Heddi, B, Schmitt, E, Mechulam, Y, Phan, A.T.
Deposit date:2018-07-03
Release date:2019-04-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:A Minimal Sequence for Left-Handed G-Quadruplex Formation.
Angew.Chem.Int.Ed.Engl., 58, 2019
1KK3
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BU of 1kk3 by Molmil
Structure of the wild-type large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi complexed with GDP-Mg2+
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ZINC ION, ...
Authors:Schmitt, E, Blanquet, S, Mechulam, Y.
Deposit date:2001-12-06
Release date:2002-04-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.
EMBO J., 21, 2002
1KK2
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BU of 1kk2 by Molmil
Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi-G235D mutant complexed with GDP-Mg2+
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ZINC ION, ...
Authors:Schmitt, E, Blanquet, S, Mechulam, Y.
Deposit date:2001-12-06
Release date:2002-04-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.
EMBO J., 21, 2002
1KK1
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BU of 1kk1 by Molmil
Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi-G235D mutant complexed with GDPNP-Mg2+
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ZINC ION, ...
Authors:Schmitt, E, Blanquet, S, Mechulam, Y.
Deposit date:2001-12-06
Release date:2002-04-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.
EMBO J., 21, 2002
1KJZ
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BU of 1kjz by Molmil
Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi-G235D mutant
Descriptor: ZINC ION, eIF2gamma
Authors:Schmitt, E, Blanquet, S, Mechulam, Y.
Deposit date:2001-12-06
Release date:2002-04-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.
EMBO J., 21, 2002
1KK0
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BU of 1kk0 by Molmil
Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi
Descriptor: ZINC ION, eIF2gamma
Authors:Schmitt, E, Blanquet, S, Mechulam, Y.
Deposit date:2001-12-06
Release date:2002-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.
EMBO J., 21, 2002
1YZ7
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BU of 1yz7 by Molmil
Crystal structure of a C-terminal segment of the alpha subunit of aIF2 from Pyrococcus abyssi
Descriptor: Probable translation initiation factor 2 alpha subunit
Authors:Yatime, L, Schmitt, E, Blanquet, S, Mechulam, Y.
Deposit date:2005-02-28
Release date:2005-06-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structure-Function Relationships of the Intact aIF2alpha Subunit from the Archaeon Pyrococcus abyssi
Biochemistry, 44, 2005
1ZQ1
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BU of 1zq1 by Molmil
Structure of GatDE tRNA-Dependent Amidotransferase from Pyrococcus abyssi
Descriptor: ASPARTIC ACID, Glutamyl-tRNA(Gln) amidotransferase subunit D, Glutamyl-tRNA(Gln) amidotransferase subunit E
Authors:Schmitt, E, Panvert, M, Blanquet, S, Mechulam, Y.
Deposit date:2005-05-18
Release date:2005-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for tRNA-Dependent Amidotransferase Function
Structure, 13, 2005
1YZ6
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BU of 1yz6 by Molmil
Crystal structure of intact alpha subunit of aIF2 from Pyrococcus abyssi
Descriptor: Probable translation initiation factor 2 alpha subunit
Authors:Yatime, L, Schmitt, E, Blanquet, S, Mechulam, Y.
Deposit date:2005-02-28
Release date:2005-06-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.37 Å)
Cite:Structure-Function Relationships of the Intact aIF2alpha Subunit from the Archaeon Pyrococcus abyssi
Biochemistry, 44, 2005
2AHO
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BU of 2aho by Molmil
Structure of the archaeal initiation factor eIF2 alpha-gamma heterodimer from Sulfolobus solfataricus complexed with GDPNP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Translation initiation factor 2 alpha subunit, ...
Authors:Yatime, L, Mechulam, Y, Blanquet, S, Schmitt, E.
Deposit date:2005-07-28
Release date:2006-01-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Switch of the gamma Subunit in an Archaeal aIF2alphagamma Heterodimer
Structure, 14, 2006
3M4X
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BU of 3m4x by Molmil
Structure of a ribosomal methyltransferase
Descriptor: NOL1/NOP2/sun family protein
Authors:Galimand, M, Schmitt, E, Panvert, M, Mechulam, Y, Courvalin, P.
Deposit date:2010-03-12
Release date:2010-04-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structure of an RNA methyltransferase
To be Published
1RQG
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BU of 1rqg by Molmil
Methionyl-tRNA synthetase from Pyrococcus abyssi
Descriptor: Methionyl-tRNA synthetase, ZINC ION
Authors:Crepin, T, Schmitt, E, Blanquet, S, Mechulam, Y.
Deposit date:2003-12-05
Release date:2004-05-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Three-dimensional structure of methionyl-tRNA synthetase from Pyrococcus abyssi.
Biochemistry, 43, 2004
3H9C
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BU of 3h9c by Molmil
Structure of methionyl-tRNA synthetase: crystal form 2
Descriptor: CITRIC ACID, Methionyl-tRNA synthetase, ZINC ION
Authors:Schmitt, E, Tanrikulu, I.C, Yoo, T.H, Panvert, M, Tirrell, D.A, Mechulam, Y.
Deposit date:2009-04-30
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Switching from an induced-fit to a lock-and-key mechanism in an aminoacyl-tRNA synthetase with modified specificity.
J.Mol.Biol., 394, 2009

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