2YII
| Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution | Descriptor: | BETA-MERCAPTOETHANOL, FORMIC ACID, GLYCEROL, ... | Authors: | Wu, B, Szymanski, W, Wybenga, G.G, Heberling, M.M, Bartsch, S, Wildeman, S, Poelarends, G.J, Feringa, B.L, Dijkstra, B.W, Janssen, D.B. | Deposit date: | 2011-05-13 | Release date: | 2011-11-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Mechanism-Inspired Engineering of Phenylalanine Aminomutase for Enhanced Beta-Regioselective Asymmetric Amination of Cinnamates. Angew.Chem.Int.Ed.Engl., 51, 2012
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6G4B
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6G4E
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6G4F
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6G4C
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6G4D
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5NH6
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5NH8
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5NHM
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5NH5
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5NHA
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5NH7
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5NH9
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5NH4
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5NHD
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5NHC
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5NHB
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5NHE
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2B4K
| Acetobacter turbidans alpha-amino acid ester hydrolase complexed with phenylglycine | Descriptor: | Alpha-amino acid ester hydrolase, D-PHENYLGLYCINE, GLYCEROL | Authors: | Barends, T.R.M, Polderman-Tijmes, J.J, Jekel, P.A, Williams, C, Wybenga, G, Janssen, D.B, Dijkstra, B.W. | Deposit date: | 2005-09-26 | Release date: | 2005-12-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Acetobacter turbidans alpha-amino acid ester hydrolase: how a single mutation improves an antibiotic-producing enzyme. J.Biol.Chem., 281, 2006
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1MPX
| ALPHA-AMINO ACID ESTER HYDROLASE LABELED WITH SELENOMETHIONINE | Descriptor: | CALCIUM ION, GLYCEROL, alpha-amino acid ester hydrolase | Authors: | Barends, T.R.M, Polderman-Tijmes, J.J, Jekel, P.A, Hensgens, C.M.H, de Vries, E.J, Janssen, D.B, Dijkstra, B.W. | Deposit date: | 2002-09-13 | Release date: | 2003-04-15 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The sequence and crystal structure of the alpha-amino acid ester hydrolase from Xanthomonas citri define a new family of beta-lactam antibiotic acylases. J.Biol.Chem., 278, 2003
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4V2R
| Ironing out their differences: Dissecting the structural determinants of a phenylalanine aminomutase and ammonia lyase | Descriptor: | PHENYLALANINE AMINOMUTASE (L-BETA-PHENYLALANINE FORMING) | Authors: | Heberling, M, Masman, M, Bartsch, S, Wybenga, G.G, Dijkstra, B.W, Marrink, S, Janssen, D. | Deposit date: | 2014-10-14 | Release date: | 2014-12-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Ironing out their differences: dissecting the structural determinants of a phenylalanine aminomutase and ammonia lyase. ACS Chem. Biol., 10, 2015
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4V2Q
| Ironing out their differences: Dissecting the structural determinants of a phenylalanine aminomutase and ammonia lyase | Descriptor: | PHENYLALANINE AMMONIA-LYASE | Authors: | Heberling, M, Masman, M, Bartsch, S, Wybenga, G.G, Dijkstra, B.W, Marrink, S, Janssen, D. | Deposit date: | 2014-10-14 | Release date: | 2014-12-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Ironing Out Their Differences: Dissecting the Structural Determinants of a Phenylalanine Aminomutase and Ammonia Lyase. Acs Chem.Biol., 10, 2015
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4ZI5
| Crystal Structure of Dienelactone Hydrolase-like Promiscuous Phospotriesterase P91 from Metagenomic Libraries | Descriptor: | CHLORIDE ION, MAGNESIUM ION, P91 | Authors: | Colin, P.-Y, Fischer, G, Hyvonen, M, Hollfelder, F. | Deposit date: | 2015-04-27 | Release date: | 2016-02-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.702 Å) | Cite: | Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics. Nat Commun, 6, 2015
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1HDE
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7AM6
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