3MG2
| Crystal structure of the orange carotenoid protein Y44S mutant from cyanobacteria synechocystis sp. PCC 6803 | Descriptor: | Orange carotenoid protein, beta,beta-caroten-4-one | Authors: | Wilson, A, Kinney, J, Zwart, P.H, Punginelli, C, D'Haen, S, Perreau, F, Klein, M.G, Kirilovsky, D, Kerfeld, C.A. | Deposit date: | 2010-04-05 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.653 Å) | Cite: | Structural determinants underlying photoprotection in the photoactive orange carotenoid protein of cyanobacteria. J.Biol.Chem., 285, 2010
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1KYJ
| Tumor Associated Mucin Motif from CD43 protein | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, Leukosialin (CD43) fragment | Authors: | Coltart, D.M, Williams, L.J, Glunz, P.W, Sames, D, Kuduk, S.D, Schwarz, J.B, Chen, X.-T, Royyuru, A.K, Danishefsky, S.D, Live, D.H. | Deposit date: | 2002-02-04 | Release date: | 2002-02-20 | Last modified: | 2020-07-29 | Method: | SOLUTION NMR | Cite: | Principles of Mucin Architecture: Structural Studies on Synthetic Glycopeptides Bearing Clustered Mono-, Di-, Tri-, and Hexasaccharide Glycodomains J.Am.Chem.Soc., 124, 2002
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1L2I
| Human Estrogen Receptor alpha Ligand-binding Domain in Complex with (R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol and a Glucocorticoid Receptor Interacting Protein 1 NR box II Peptide | Descriptor: | (R,R)-5,11-CIS-DIETHYL-5,6,11,12-TETRAHYDROCHRYSENE-2,8-DIOL, CHLORIDE ION, ESTROGEN RECEPTOR, ... | Authors: | Shiau, A.K, Barstad, D, Radek, J.T, Meyers, M.J, Nettles, K.W, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Agard, D.A, Greene, G.L. | Deposit date: | 2002-02-21 | Release date: | 2002-05-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism. Nat.Struct.Biol., 9, 2002
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6KJ3
| 120kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.60 A | Descriptor: | RNA-binding protein FUS | Authors: | Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X. | Deposit date: | 2019-07-20 | Release date: | 2019-10-02 | Last modified: | 2024-03-27 | Method: | ELECTRON CRYSTALLOGRAPHY (0.6 Å) | Cite: | Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules. Anal.Chem., 91, 2019
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3FXU
| Crystal structure of TsaR in complex with its effector p-toluenesulfonate | Descriptor: | CHLORIDE ION, FORMIC ACID, GLYCEROL, ... | Authors: | Monferrer, D, Tralau, T, Kertesz, M.A, Kikhney, A, Svergun, D, Uson, I. | Deposit date: | 2009-01-21 | Release date: | 2010-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural studies on the full-length LysR-type regulator TsaR from Comamonas testosteroni T-2 reveal a novel open conformation of the tetrameric LTTR fold Mol.Microbiol., 75, 2010
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1LR4
| Room Temperature Crystal Structure of the Apo-form of the catalytic subunit of protein kinase CK2 from Zea mays | Descriptor: | BENZAMIDINE, Protein kinase CK2 | Authors: | Niefind, K, Puetter, M, Guerra, B, Issinger, O.-G, Schomburg, D. | Deposit date: | 2002-05-14 | Release date: | 2002-05-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Inclining the purine base binding plane in protein kinase CK2 by exchanging the flanking side-chains generates a preference for ATP as a cosubstrate. J.Mol.Biol., 347, 2005
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1LJO
| CRYSTAL STRUCTURE OF AN SM-LIKE PROTEIN (AF-SM2) FROM ARCHAEOGLOBUS FULGIDUS AT 1.95A RESOLUTION | Descriptor: | ACETIC ACID, Archaeal Sm-like protein AF-Sm2, CADMIUM ION | Authors: | Toro, I, Basquin, J, Teo-Dreher, H, Suck, D. | Deposit date: | 2002-04-22 | Release date: | 2002-07-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Archaeal Sm proteins form heptameric and hexameric complexes: crystal structures of the Sm1 and Sm2 proteins from the hyperthermophile Archaeoglobus fulgidus. J.Mol.Biol., 320, 2002
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1KKS
| Structure of the histone mRNA hairpin required for cell cycle regulation of histone gene expression | Descriptor: | 5'-R(*GP*GP*AP*AP*GP*GP*CP*CP*CP*UP*UP*UP*UP*CP*AP*GP*GP*GP*CP*CP*AP*CP*CP*C)-3' | Authors: | Zanier, K, Luyten, I, Crombie, C, Muller, B, Schuemperli, D, Linge, J.P, Nilges, M, Sattler, M. | Deposit date: | 2001-12-10 | Release date: | 2002-03-13 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of the histone mRNA hairpin required for cell cycle regulation of histone gene expression. RNA, 8, 2002
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1KCZ
| Crystal Structure of beta-methylaspartase from Clostridium tetanomorphum. Mg-complex. | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, beta-methylaspartase | Authors: | Asuncion, M, Blankenfeldt, W, Barlow, J.N, Gani, D, Naismith, J.H. | Deposit date: | 2001-11-12 | Release date: | 2001-12-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step. J.Biol.Chem., 277, 2002
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1XJO
| STRUCTURE OF AMINOPEPTIDASE | Descriptor: | AMINOPEPTIDASE, CALCIUM ION, PHOSPHATE ION, ... | Authors: | Greenblatt, H.M, Barra, D, Blumberg, S, Shoham, G. | Deposit date: | 1996-10-09 | Release date: | 1997-04-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Streptomyces griseus aminopeptidase: X-ray crystallographic structure at 1.75 A resolution. J.Mol.Biol., 265, 1997
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1BY5
| FHUA FROM E. COLI, WITH ITS LIGAND FERRICHROME | Descriptor: | FE (III) ION, FERRIC HYDROXAMATE UPTAKE PROTEIN, FERRICHROME, ... | Authors: | Locher, K.P, Rees, B, Koebnik, R, Mitschler, A, Moulinier, L, Rosenbusch, J.P, Moras, D. | Deposit date: | 1998-10-23 | Release date: | 1999-01-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Transmembrane signaling across the ligand-gated FhuA receptor: crystal structures of free and ferrichrome-bound states reveal allosteric changes. Cell(Cambridge,Mass.), 95, 1998
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3DSD
| Crystal structure of P. furiosus Mre11-H85S bound to a branched DNA and manganese | Descriptor: | DNA (5'-D(*DCP*DGP*DCP*DGP*DCP*DAP*DCP*DAP*DAP*DGP*DCP*DTP*DTP*DTP*DTP*DGP*DCP*DTP*DTP*DGP*DTP*DGP*DGP*DAP*DTP*DA)-3'), DNA double-strand break repair protein mre11, MANGANESE (II) ION | Authors: | Williams, R.S, Moiani, D, Tainer, J.A. | Deposit date: | 2008-07-11 | Release date: | 2008-10-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair. Cell(Cambridge,Mass.), 135, 2008
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1ZUR
| Crystal structure of spin labeled T4 Lysozyme (V131R1F) | Descriptor: | CHLORIDE ION, Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-4-phenyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | Authors: | Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L. | Deposit date: | 2005-05-31 | Release date: | 2006-10-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of spin labeled T4 Lysozyme (V131R1F) To be Published
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6I3S
| Crystal structure of MDM2 in complex with compound 13. | Descriptor: | (3~{S},3'~{R},3'~{a}~{S},6'~{a}~{R})-6-chloranyl-3'-(3-chloranyl-2-fluoranyl-phenyl)-1'-(cyclopropylmethyl)spiro[1~{H}-indole-3,2'-3~{a},6~{a}-dihydro-3~{H}-pyrrolo[3,4-b]pyrrole]-2,4'-dione, E3 ubiquitin-protein ligase Mdm2, GLYCEROL, ... | Authors: | Bader, G, Kessler, D. | Deposit date: | 2018-11-07 | Release date: | 2018-12-19 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Targeted Synthesis of Complex Spiro[3H-indole-3,2'-pyrrolidin]-2(1H)-ones by Intramolecular Cyclization of Azomethine Ylides: Highly Potent MDM2-p53 Inhibitors. ChemMedChem, 14, 2019
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7FDS
| High resolution crystal structure of LpqH from Mycobacterium tuberculosis | Descriptor: | Lipoprotein LpqH | Authors: | Kundapura, S.V, Chatterjee, S, Samanta, D, Ramagopal, U.A. | Deposit date: | 2021-07-17 | Release date: | 2021-12-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.258 Å) | Cite: | High-resolution crystal structure of LpqH, an immunomodulatory surface lipoprotein of Mycobacterium tuberculosis reveals a distinct fold and a conserved cleft on its surface. Int.J.Biol.Macromol., 210, 2022
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1L6H
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1ZS2
| Amylosucrase Mutant E328Q in a ternary complex with sucrose and maltoheptaose | Descriptor: | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, amylosucrase, ... | Authors: | Skov, L.K, Mirza, O, Sprogoe, D, van der Veen, B.A, Remaud-Simeon, M, Albenne, C, Monsan, P, Gajhede, M. | Deposit date: | 2005-05-23 | Release date: | 2006-05-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Crystal structure of the Glu328Gln mutant of Neisseria polysaccharea amylosucrase in complex with sucrose and maltoheptaose BIOCATAL.BIOTRANSFOR., 24, 2006
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1LJ0
| Structure of quintuple mutant of the rat outer mitocondrial cytochrome b5. | Descriptor: | Cytochrome B5 outer mitochondrial membrane isoform, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Cowley, A.B, Altuve, A, Kuchment, O, Terzyan, S, Zhang, X.C, Rivera, M, Benson, D. | Deposit date: | 2002-04-18 | Release date: | 2002-11-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Toward engineering the stability and hemin binding properties
of microsomal cytochromes b5 into rat outer mitochondrial cytochrome b5:
Examining the influence of residues 25 and 71. Biochemistry, 41, 2002
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6IC9
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2ACU
| TYROSINE-48 IS THE PROTON DONOR AND HISTIDINE-110 DIRECTS SUBSTRATE STEREOCHEMICAL SELECTIVITY IN THE REDUCTION REACTION OF HUMAN ALDOSE REDUCTASE: ENZYME KINETICS AND THE CRYSTAL STRUCTURE OF THE Y48H MUTANT ENZYME | Descriptor: | ALDOSE REDUCTASE, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Bohren, K.M, Grimshaw, C.E, Lai, C.-J, Gabbay, K.H, Petsko, G.A, Harrison, D.H, Ringe, D. | Deposit date: | 1994-04-15 | Release date: | 1994-07-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Tyrosine-48 is the proton donor and histidine-110 directs substrate stereochemical selectivity in the reduction reaction of human aldose reductase: enzyme kinetics and crystal structure of the Y48H mutant enzyme. Biochemistry, 33, 1994
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1DAW
| CRYSTAL STRUCTURE OF A BINARY COMPLEX OF PROTEIN KINASE CK2 (ALPHA-SUBUNIT) AND MG-AMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROTEIN KINASE CK2 | Authors: | Niefind, K, Puetter, M, Guerra, B, Issinger, O.G, Schomburg, D. | Deposit date: | 1999-11-01 | Release date: | 2000-05-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | GTP plus water mimic ATP in the active site of protein kinase CK2. Nat.Struct.Biol., 6, 1999
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1DJ9
| CRYSTAL STRUCTURE OF 8-AMINO-7-OXONANOATE SYNTHASE (OR 7-KETO-8AMINIPELARGONATE OR KAPA SYNTHASE) COMPLEXED WITH PLP AND THE PRODUCT 8(S)-AMINO-7-OXONANONOATE (OR KAPA). THE ENZYME OF BIOTIN BIOSYNTHETIC PATHWAY. | Descriptor: | 8-AMINO-7-OXONONANOATE SYNTHASE, MAGNESIUM ION, N-[7-KETO-8-AMINOPELARGONIC ACID]-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], ... | Authors: | Webster, S.P, Alexeev, D, Campopiano, D.J, Watt, R.M, Alexeeva, M, Sawyer, L, Baxter, R.L. | Deposit date: | 1999-12-02 | Release date: | 2000-12-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies. Biochemistry, 39, 2000
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1DDT
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2A86
| Crystal structure of A Pantothenate synthetase complexed with AMP and beta-alanine | Descriptor: | ADENOSINE MONOPHOSPHATE, BETA-ALANINE, ETHANOL, ... | Authors: | Wang, S, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2005-07-07 | Release date: | 2006-02-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal Structure of the Pantothenate Synthetase from Mycobacterium tuberculosis, Snapshots of the Enzyme in Action. Biochemistry, 45, 2006
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1DLA
| NOVEL NADPH-BINDING DOMAIN REVEALED BY THE CRYSTAL STRUCTURE OF ALDOSE REDUCTASE | Descriptor: | ALDOSE REDUCTASE | Authors: | Rondeau, J.-M, Tete-Favier, F, Podjarny, A, Reymann, J.-M, Barth, P, Biellmann, J.-F, Moras, D. | Deposit date: | 1993-02-08 | Release date: | 1994-04-30 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Novel NADPH-binding domain revealed by the crystal structure of aldose reductase. Nature, 355, 1992
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