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6MZJ
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BU of 6mzj by Molmil
Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 2 Fabs bound, sharpened map
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ...
Authors:Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D.
Deposit date:2018-11-05
Release date:2018-11-14
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
7PHC
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BU of 7phc by Molmil
70S ribosome with A*- and P/E-site tRNAs in chloramphenicol-treated Mycoplasma pneumoniae cells
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-08-16
Release date:2022-05-25
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (9.9 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
7PHB
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BU of 7phb by Molmil
70S ribosome with A- and P-site tRNAs in chloramphenicol-treated Mycoplasma pneumoniae cells
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-08-16
Release date:2022-05-25
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
1SVY
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BU of 1svy by Molmil
SEVERIN DOMAIN 2, 1.75 ANGSTROM CRYSTAL STRUCTURE
Descriptor: CALCIUM ION, SEVERIN, SODIUM ION
Authors:Puius, Y.A, Fedorov, E.V, Eichinger, L, Sullivan, M, Schleicher, M, Almo, S.C.
Deposit date:1998-08-10
Release date:1999-08-10
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mapping the functional surface of domain 2 in the gelsolin superfamily.
Biochemistry, 39, 2000
6N7M
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BU of 6n7m by Molmil
1.78 Angstrom Resolution Crystal Structure of Hypothetical Protein CD630_05490 from Clostridioides difficile 630.
Descriptor: Hypothetical Protein CD630_05490
Authors:Minasov, G, Shuvalova, L, Wawrzak, Z, Kiryukhina, O, Dubrovska, I, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-11-27
Release date:2018-12-12
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:1.78 Angstrom Resolution Crystal Structure of Hypothetical Protein CD630_05490 from Clostridioides difficile 630.
To Be Published
7PH9
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BU of 7ph9 by Molmil
70S ribosome with P-site tRNA in chloramphenicol-treated Mycoplasma pneumoniae cells
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-08-16
Release date:2022-05-25
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
6N86
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BU of 6n86 by Molmil
Resistance to inhibitors of cholinesterase 8A (Ric8A) protein
Descriptor: Synembryn-A
Authors:Srivastava, D, Gakhar, L, Artemyev, N.O.
Deposit date:2018-11-28
Release date:2019-07-10
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural underpinnings of Ric8A function as a G-protein alpha-subunit chaperone and guanine-nucleotide exchange factor.
Nat Commun, 10, 2019
6N8P
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BU of 6n8p by Molmil
Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2). Unphosphorylated, crystal form 1.
Descriptor: CHLORIDE ION, Lethal(2) giant larvae protein homolog 2
Authors:Almagor, L, Weis, W.I.
Deposit date:2018-11-30
Release date:2019-05-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.193 Å)
Cite:Structural insights into the aPKC regulatory switch mechanism of the human cell polarity protein lethal giant larvae 2.
Proc.Natl.Acad.Sci.USA, 116, 2019
1IDA
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BU of 1ida by Molmil
CRYSTAL STRUCTURES OF HIV-2 PROTEASE IN COMPLEX WITH INHIBITORS CONTAINING THE HYDROXYETHYLAMINE DIPEPTIDE ISOSTERE
Descriptor: N-[(1R)-1-{[(1S,2S)-1-benzyl-3-{(2R,4S)-2-(tert-butylcarbamoyl)-4-[(pyridin-3-ylmethyl)sulfanyl]piperidin-1-yl}-2-hydroxypropyl]carbamoyl}-2-methylpropyl]quinoline-2-carboxamide, Protease
Authors:Tong, L, Anderson, P.C.
Deposit date:1994-10-19
Release date:1995-01-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of HIV-2 protease in complex with inhibitors containing the hydroxyethylamine dipeptide isostere.
Structure, 3, 1995
6MNL
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BU of 6mnl by Molmil
NMR solution structures of second bromodomain of BRD4 with FOXO3a peptide
Descriptor: Bromodomain-containing protein 4, FOXO3a peptide
Authors:Zeng, L, Zhou, M.-M.
Deposit date:2018-10-02
Release date:2018-10-31
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer.
Nat Commun, 9, 2018
6NPL
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BU of 6npl by Molmil
Cryo-EM structure of NKCC1
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ...
Authors:Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
Deposit date:2019-01-17
Release date:2019-07-31
Last modified:2019-08-28
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
1I5N
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BU of 1i5n by Molmil
Crystal structure of the P1 domain of CheA from Salmonella typhimurium
Descriptor: CHEMOTAXIS PROTEIN CHEA, SULFATE ION
Authors:Mourey, L, Da Re, S, Pedelacq, J.-D, Tolstyk, T, Faurie, C, Guillet, V, Stock, J.B, Samama, J.-P.
Deposit date:2001-02-28
Release date:2001-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystal structure of the CheA histidine phosphotransfer domain that mediates response regulator phosphorylation in bacterial chemotaxis
J.Biol.Chem., 276, 2001
1I7E
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BU of 1i7e by Molmil
C-Terminal Domain Of Mouse Brain Tubby Protein bound to Phosphatidylinositol 4,5-bis-phosphate
Descriptor: L-ALPHA-GLYCEROPHOSPHO-D-MYO-INOSITOL-4,5-BIS-PHOSPHATE, TUBBY PROTEIN
Authors:Santagata, S, Boggon, T.J, Baird, C.L, Shan, W.S, Shapiro, L.
Deposit date:2001-03-08
Release date:2001-06-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:G-protein signaling through tubby proteins.
Science, 292, 2001
1L2X
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BU of 1l2x by Molmil
Atomic Resolution Crystal Structure of a Viral RNA Pseudoknot
Descriptor: MAGNESIUM ION, POTASSIUM ION, RNA pseudoknot, ...
Authors:Egli, M, Minasov, G, Su, L, Rich, A.
Deposit date:2002-02-25
Release date:2002-03-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Metal ions and flexibility in a viral RNA pseudoknot at atomic resolution.
Proc.Natl.Acad.Sci.USA, 99, 2002
3DP1
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BU of 3dp1 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3n
Descriptor: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, BENZAMIDINE, CHLORIDE ION, ...
Authors:Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H.
Deposit date:2008-07-07
Release date:2009-05-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
2IAM
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BU of 2iam by Molmil
Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
Descriptor: 15-mer peptide from Triosephosphate isomerase, CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain, ...
Authors:Deng, L, Langley, R.J, Mariuzza, R.A.
Deposit date:2006-09-08
Release date:2007-04-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
3DP0
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BU of 3dp0 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3m
Descriptor: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, BENZAMIDINE, CHLORIDE ION, ...
Authors:Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H.
Deposit date:2008-07-07
Release date:2009-05-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
6NIG
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BU of 6nig by Molmil
Crystal structure of the human TLR2-Diprovocim complex
Descriptor: (3S,4S,3'S,4'S)-1,1'-(1,4-phenylenedicarbonyl)bis{N~3~,N~4~-bis[(1S,2R)-2-phenylcyclopropyl]pyrrolidine-3,4-dicarboxami de}, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhang, H, Beutler, B.A, Tomchick, D.R, Su, L.
Deposit date:2018-12-27
Release date:2019-04-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis of TLR2/TLR1 Activation by the Synthetic Agonist Diprovocim.
J. Med. Chem., 62, 2019
6NAU
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BU of 6nau by Molmil
1.55 Angstrom Resolution Crystal Structure of 6-phosphogluconolactonase from Klebsiella pneumoniae
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-phosphogluconolactonase, CHLORIDE ION
Authors:Minasov, G, Shuvalova, L, Pshenychnyi, S, Dubrovska, I, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-12-06
Release date:2018-12-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A Structural Systems Biology Approach to High-Risk CG23 Klebsiella pneumoniae.
Microbiol Resour Announc, 12, 2023
6NBU
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BU of 6nbu by Molmil
CRISPR Complex Subunit Csm2 from Staphylococcus epidermidis RP62a
Descriptor: CRISPR-associated protein
Authors:Dorsey, B.W, Huang, L, Mondragon, A.
Deposit date:2018-12-10
Release date:2019-02-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural organization of a Type III-A CRISPR effector subcomplex determined by X-ray crystallography and cryo-EM.
Nucleic Acids Res., 47, 2019
6O2R
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BU of 6o2r by Molmil
Deacetylated Microtubules
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Eshun-Wilson, L, Zhang, R, Portran, D, Nachury, M.V, Toso, D, Lohr, T, Vendruscolo, M, Bonomi, M, Fraser, J.S, Nogales, E.
Deposit date:2019-02-24
Release date:2019-05-22
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Effects of alpha-tubulin acetylation on microtubule structure and stability.
Proc.Natl.Acad.Sci.USA, 116, 2019
3FXT
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BU of 3fxt by Molmil
Crystal structure of the N-terminal domain of human NUDT6
Descriptor: GLYCEROL, Nucleoside diphosphate-linked moiety X motif 6
Authors:Tresaugues, L, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nyman, T, Persson, C, Sagemark, J, Schueler, H, Siponen, M.I, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Wikstrom, M, Nordlund, P, Structural Genomics Consortium (SGC)
Deposit date:2009-01-21
Release date:2009-03-03
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the N-terminal domain of human NUDT6
To be Published
6NXV
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BU of 6nxv by Molmil
Crystal structure of the theta class glutathione S-transferase from the citrus canker pathogen Xanthomonas axonopodis pv. citri, apo form
Descriptor: CHLORIDE ION, DIMETHYL SULFOXIDE, Glutathione S-transferase
Authors:Hilario, E, De Keyser, S, Fan, L.
Deposit date:2019-02-10
Release date:2020-03-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural and biochemical characterization of a glutathione transferase from the citrus canker pathogen Xanthomonas.
Acta Crystallogr D Struct Biol, 76, 2020
6O15
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BU of 6o15 by Molmil
Crystal structure of a putative oxidoreductase YjhC from Escherichia coli in complex with NAD(H)
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, Uncharacterized oxidoreductase YjhC
Authors:Horne, C.R, Kind, L, Davies, J.S, Dobson, R.C.
Deposit date:2019-02-17
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:On the structure and function of Escherichia coli YjhC: An oxidoreductase involved in bacterial sialic acid metabolism.
Proteins, 88, 2020
3G1U
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BU of 3g1u by Molmil
Crystal structure of Leishmania major S-adenosylhomocysteine hydrolase
Descriptor: ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Siponen, M.I, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Schutz, P, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Wisniewska, M, Schueler, H, Structural Genomics Consortium (SGC)
Deposit date:2009-01-30
Release date:2009-02-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Leishmania major S-adenosylhomocysteine hydrolase
To be Published

222624

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