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6MZI
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BU of 6mzi by Molmil
CryoEM structure of human enterovirus D68 expanded 1 particle (pH 6.5, 4 degrees Celsius, 3 min)
Descriptor: viral protein 1, viral protein 2, viral protein 3, ...
Authors:Liu, Y, Rossmann, M.G.
Deposit date:2018-11-05
Release date:2018-12-19
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8R9X
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BU of 8r9x by Molmil
Local refinement of the PDCoV spike glycoprotein ectodomain in complex with the 22C10 antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Debski-Antoniak, O, Hurdiss, D.L.
Deposit date:2023-11-30
Release date:2024-06-05
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein.
Nat Commun, 15, 2024
8R9Z
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BU of 8r9z by Molmil
S1B domain of the PDCoV spike glycoprotein in complex with the 67B12 and 46E6 antibody Fab fragments
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 46E6 antibody heavy chain, ...
Authors:Debski-Antoniak, O, Hurdiss, D.L.
Deposit date:2023-11-30
Release date:2024-06-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein.
Nat Commun, 15, 2024
8R9Y
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BU of 8r9y by Molmil
S1B domain of the PDCoV spike glycoprotein in complex with the 67B12 and 42H3 antibody Fab fragments
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 42H3 antibody heavy chain, ...
Authors:Debski-Antoniak, O, Hurdiss, D.L.
Deposit date:2023-11-30
Release date:2024-06-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein.
Nat Commun, 15, 2024
8R9W
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BU of 8r9w by Molmil
PDCoV spike glycoprotein ectodomain in complex with the 22C10 antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 22C10 antibody heavy chain, ...
Authors:Debski-Antoniak, O, Hurdiss, D.L.
Deposit date:2023-11-30
Release date:2024-06-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein.
Nat Commun, 15, 2024
8OHN
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BU of 8ohn by Molmil
Human Coronavirus HKU1 spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Pronker, M.F, Hurdiss, D.L.
Deposit date:2023-03-21
Release date:2023-08-02
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Sialoglycan binding triggers spike opening in a human coronavirus.
Nature, 624, 2023
8OPN
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BU of 8opn by Molmil
Human Coronavirus HKU1 spike glycoprotein in complex with an alpha2,8-linked 9-O-acetylated disialoside (1-up state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid-(2-8)-N-acetyl-alpha-neuraminic acid, ...
Authors:Pronker, M.F, Creutznacher, R, Hurdiss, D.L.
Deposit date:2023-04-07
Release date:2023-08-02
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Sialoglycan binding triggers spike opening in a human coronavirus.
Nature, 624, 2023
8OPO
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BU of 8opo by Molmil
Human Coronavirus HKU1 spike glycoprotein in complex with an alpha2,8-linked 9-O-acetylated disialoside (3-up state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid-(2-8)-N-acetyl-alpha-neuraminic acid, ...
Authors:Pronker, M.F, Creutznacher, R, Hurdiss, D.L.
Deposit date:2023-04-07
Release date:2023-08-02
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Sialoglycan binding triggers spike opening in a human coronavirus.
Nature, 624, 2023
8OPM
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BU of 8opm by Molmil
Human Coronavirus HKU1 spike glycoprotein in complex with an alpha2,8-linked 9-O-acetylated disialoside (closed state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid-(2-8)-N-acetyl-alpha-neuraminic acid, ...
Authors:Pronker, M.F, Creutznacher, R, Hurdiss, D.L.
Deposit date:2023-04-07
Release date:2023-08-02
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Sialoglycan binding triggers spike opening in a human coronavirus.
Nature, 624, 2023
6EIT
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BU of 6eit by Molmil
Coxsackievirus A24v in complex with the D1-D2 fragment of ICAM-1
Descriptor: Intercellular adhesion molecule 1, VP1, VP2, ...
Authors:Hurdiss, D.L, Ranson, N.A.
Deposit date:2017-09-19
Release date:2018-01-10
Last modified:2018-01-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7PNM
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BU of 7pnm by Molmil
Human coronavirus OC43 spike glycoprotein ectodomain in complex with the 46C12 antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 46C12 antibody heavy chain, ...
Authors:Hurdiss, D.L.
Deposit date:2021-09-07
Release date:2022-04-20
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes.
Nat Commun, 13, 2022
7PO5
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BU of 7po5 by Molmil
Human coronavirus OC43 spike glycoprotein ectodomain in complex with the 47C9 antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 47C9 antibody heavy chain, 47C9 antibody light chain, ...
Authors:Hurdiss, D.L.
Deposit date:2021-09-08
Release date:2022-04-20
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes.
Nat Commun, 13, 2022
7PNQ
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BU of 7pnq by Molmil
Human coronavirus OC43 spike glycoprotein ectodomain in complex with the 43E6 antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 43E6 antibody heavy chain, 43E6 antibody light chain, ...
Authors:Hurdiss, D.L.
Deposit date:2021-09-07
Release date:2022-04-20
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes.
Nat Commun, 13, 2022
6QFY
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BU of 6qfy by Molmil
CRYSTAL STRUCTURE OF PORCINE HEMAGGLUTINATING ENCEPHALOMYELITIS VIRUS SPIKE PROTEIN LECTIN DOMAIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Huizinga, E.G, Bakkers, M, Lang, Y.
Deposit date:2019-01-10
Release date:2019-02-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain A.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
8BON
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BU of 8bon by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the macrocyclic peptide S1B3inL1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrocyclic peptide S1B3inL1, ...
Authors:Hurdiss, D.L.
Deposit date:2022-11-15
Release date:2023-06-28
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein.
Proc.Natl.Acad.Sci.USA, 120, 2023
8C8P
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BU of 8c8p by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the 10D12 heavy-chain-only antibody (local refinement)
Descriptor: Heavy-chain-only antibody 10D12, Spike glycoprotein,SARS-CoV-2 spike glycoprotein
Authors:Serna Martin, I, Hurdiss, D.L.
Deposit date:2023-01-20
Release date:2023-02-22
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Avidity engineering of human heavy-chain-only antibodies mitigates neutralization resistance of SARS-CoV-2 variants.
Front Immunol, 14, 2023
6FFA
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BU of 6ffa by Molmil
FMDV Leader protease bound to substrate ISG15
Descriptor: GLYCEROL, Lbpro, SULFATE ION, ...
Authors:Swatek, K.N, Pruneda, J.N, Komander, D.
Deposit date:2018-01-05
Release date:2018-02-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CV5
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BU of 6cv5 by Molmil
CryoEM structure of human enterovirus D68 full particle (after incubation with low molecular weight heparin)
Descriptor: viral protein 1, viral protein 2, viral protein 3, ...
Authors:Liu, Y, Rossmann, M.G.
Deposit date:2018-03-27
Release date:2019-07-24
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Bypassing pan-enterovirus host factor PLA2G16.
Nat Commun, 10, 2019
6CRS
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BU of 6crs by Molmil
CryoEM structure of human enterovirus D68 A-particle (pH 7.2 and 4 degrees Celsius)
Descriptor: viral protein 1, viral protein 2, viral protein 3
Authors:Liu, Y, Rossmann, M.G.
Deposit date:2018-03-19
Release date:2018-12-19
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CV4
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BU of 6cv4 by Molmil
CryoEM structure of human enterovirus D68 emptied particle (after incubation with low molecular weight heparin)
Descriptor: viral protein 1, viral protein 2, viral protein 3
Authors:Liu, Y, Rossmann, M.G.
Deposit date:2018-03-27
Release date:2019-07-24
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Bypassing pan-enterovirus host factor PLA2G16.
Nat Commun, 10, 2019
6CRU
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BU of 6cru by Molmil
CryoEM structure of human enterovirus D68 emptied particle (pH 7.2 and 4 degrees Celsius)
Descriptor: viral protein 1, viral protein 2, viral protein 3
Authors:Liu, Y, Rossmann, M.G.
Deposit date:2018-03-19
Release date:2018-12-19
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CS4
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BU of 6cs4 by Molmil
CryoEM structure of human enterovirus D68 A-particle (pH 5.5 and 33 degrees Celsius)
Descriptor: viral protein 1, viral protein 2, viral protein 3
Authors:Liu, Y, Rossmann, M.G.
Deposit date:2018-03-19
Release date:2018-12-19
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CS6
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BU of 6cs6 by Molmil
CryoEM structure of human enterovirus D68 A-particle (pH 5.5 and room temperature)
Descriptor: viral protein 1, viral protein 2, viral protein 3
Authors:Liu, Y, Rossmann, M.G.
Deposit date:2018-03-19
Release date:2018-12-19
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CV2
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BU of 6cv2 by Molmil
CryoEM structure of human enterovirus D68 full virion
Descriptor: viral protein 1, viral protein 2, viral protein 3, ...
Authors:Liu, Y, Rossmann, M.G.
Deposit date:2018-03-27
Release date:2019-07-24
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Bypassing pan-enterovirus host factor PLA2G16.
Nat Commun, 10, 2019
6CRP
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BU of 6crp by Molmil
CryoEM structure of human enterovirus D68 abortive product 1 (pH 7.2 and 4 degrees Celsius)
Descriptor: viral protein 1, viral protein 2, viral protein 3, ...
Authors:Liu, Y, Rossmann, M.G.
Deposit date:2018-03-19
Release date:2018-12-19
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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