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5AIQ
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BU of 5aiq by Molmil
Crystal structure of ligand-free NadR
Descriptor: TRANSCRIPTIONAL REGULATOR, MARR FAMILY
Authors:Liguori, A, Malito, E, Bottomley, M.J.
Deposit date:2015-02-16
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.716 Å)
Cite:Molecular Basis of Ligand-Dependent Regulation of Nadr, the Transcriptional Repressor of Meningococcal Virulence Factor Nada.
Plos Pathog., 12, 2016
5AIP
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BU of 5aip by Molmil
Crystal structure of NadR in complex with 4-hydroxyphenylacetate
Descriptor: 4-HYDROXYPHENYLACETATE, TRANSCRIPTIONAL REGULATOR, MARR FAMILY
Authors:Liguori, A, Malito, E, Bottomley, M.J.
Deposit date:2015-02-16
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Basis of Ligand-Dependent Regulation of Nadr, the Transcriptional Repressor of Meningococcal Virulence Factor Nada.
Plos Pathog., 12, 2016
2Y7S
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BU of 2y7s by Molmil
Structure of a designed meningococcal antigen (factor H binding protein, mutant G1) inducing broad protective immunity
Descriptor: FACTOR H BINDING PROTEIN
Authors:Malito, E, Spraggon, G, Bottomley, M.J.
Deposit date:2011-02-01
Release date:2011-07-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity.
Sci.Transl.Med, 3, 2011
6EUN
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BU of 6eun by Molmil
Crystal structure of Neisseria meningitidis vaccine antigen NadA variant 3
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, ...
Authors:Dello Iacono, L, Liguori, A, Malito, E, Bottomley, M.J.
Deposit date:2017-10-30
Release date:2018-10-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:NadA3 Structures Reveal Undecad Coiled Coils and LOX1 Binding Regions Competed by Meningococcus B Vaccine-Elicited Human Antibodies.
MBio, 9, 2018
6EUP
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BU of 6eup by Molmil
Crystal structure of Neisseria meningitidis NadA variant 3 double mutant A33I-I38L
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, Adhesin A, ...
Authors:Dello Iacono, L, Liguori, A, Malito, E, Bottomley, M.J.
Deposit date:2017-10-31
Release date:2018-10-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:NadA3 Structures Reveal Undecad Coiled Coils and LOX1 Binding Regions Competed by Meningococcus B Vaccine-Elicited Human Antibodies.
MBio, 9, 2018
4B8Y
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BU of 4b8y by Molmil
Ferrichrome-bound FhuD2
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, FE (III) ION, ...
Authors:Malito, E, Bottomley, M.J, Spraggon, G.
Deposit date:2012-08-31
Release date:2012-11-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Functional Characterization of the Staphylococcus Aureus Virulence Factor and Vaccine Candidate Fhud2.
Biochem.J., 449, 2013
5N4G
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BU of 5n4g by Molmil
human Fab fragment 12E1 against NHBA from Neisseria meningitidis
Descriptor: 1,2-ETHANEDIOL, HEAVY CHAIN, LIGHT CHAIN, ...
Authors:Maritan, M, Malito, E.
Deposit date:2017-02-10
Release date:2017-05-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structures of human Fabs targeting the Bexsero meningococcal vaccine antigen NHBA.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5NYX
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BU of 5nyx by Molmil
human Fab fragment 5H2 against NHBA from Neisseria meningitidis
Descriptor: GLYCEROL, HEAVY CHAIN, LIGHT CHAIN, ...
Authors:Malito, E, Maritan, M.
Deposit date:2017-05-12
Release date:2018-05-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody.
PLoS ONE, 13, 2018
5N4J
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BU of 5n4j by Molmil
human Fab fragment 10C3 against NHBA from Neisseria meningitidis
Descriptor: HEAVY CHAIN, LIGHT CHAIN
Authors:Maritan, M, Malito, E.
Deposit date:2017-02-10
Release date:2017-05-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.503 Å)
Cite:Crystal structures of human Fabs targeting the Bexsero meningococcal vaccine antigen NHBA.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5O1R
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BU of 5o1r by Molmil
human Fab 5H2 bound to NHBA-C3 from Neisseria meningitidis serogroup B
Descriptor: 1,2-ETHANEDIOL, GNA2132, IGH@ protein, ...
Authors:Malito, E, Maritan, M.
Deposit date:2017-05-19
Release date:2018-05-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody.
PLoS ONE, 13, 2018
4CJD
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BU of 4cjd by Molmil
Crystal structure of Neisseria meningitidis trimeric autotransporter and vaccine antigen NadA
Descriptor: IODIDE ION, NADA
Authors:Malito, E, Biancucci, M, Spraggon, G, Bottomley, M.J.
Deposit date:2013-12-19
Release date:2014-11-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.056 Å)
Cite:Structure of the Meningococcal Vaccine Antigen Nada and Epitope Mapping of a Bactericidal Antibody.
Proc.Natl.Acad.Sci.USA, 111, 2014
4BIG
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BU of 4big by Molmil
Crystal structure of the conserved staphylococcal antigen 1B, Csa1B
Descriptor: UNCHARACTERIZED LIPOPROTEIN SAOUHSC_00053
Authors:Malito, E, Bottomley, M.J, Schluepen, C, Liberatori, S.
Deposit date:2013-04-10
Release date:2013-08-07
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (2.274 Å)
Cite:Mining the Bacterial Unknown Proteome: Identification and Characterization of a Novel Family of Highly Conserved Protective Antigens in Staphylococcus Aureus
Biochem.J., 455, 2013
4BIH
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BU of 4bih by Molmil
Crystal structure of the conserved staphylococcal antigen 1A, Csa1A
Descriptor: CALCIUM ION, UNCHARACTERIZED LIPOPROTEIN SAOUHSC_00053
Authors:Malito, E, Bottomley, M.J, Spraggon, G, Schluepen, C, Liberatori, S.
Deposit date:2013-04-10
Release date:2013-08-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.459 Å)
Cite:Mining the Bacterial Unknown Proteome: Identification and Characterization of a Novel Family of Highly Conserved Protective Antigens in Staphylococcus Aureus
Biochem.J., 455, 2013
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