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Crystal structure of an RNA aptamer in complex with fluorophore and Fab
Descriptor:	4-(3,5-difluoro-4-hydroxybenzyl)-1,2-dimethyl-1H-imidazol-5-ol, BL3-6 Fab antibody, heavy chain, ...
Authors:	Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A.
Deposit date:	2013-05-29
Release date:	2014-06-18
Last modified:	2024-11-20
Method:	X-RAY DIFFRACTION (2.186 Å)
Cite:	A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat.Chem.Biol., 10, 2014

Crystal structure of Pepper RNA aptamer in complex with HBC599 ligand and Fab BL3-6
Descriptor:	4-[(Z)-1-cyano-2-{6-[(2-hydroxyethyl)(methyl)amino]-1-benzothiophen-2-yl}ethenyl]benzonitrile, Fab BL3-6 heavy chain, Fab BL3-6 light chain, ...
Authors:	Rees, H.C, Piccirilli, J.A.
Deposit date:	2022-02-19
Release date:	2022-08-31
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (2.66 Å)
Cite:	Structural Basis for Fluorescence Activation by Pepper RNA. Acs Chem.Biol., 17, 2022

Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with RU39411
Descriptor:	11alpha-{4-[2-(dimethylamino)ethoxy]phenyl}estra-1(10),2,4-triene-3,17beta-diol, Estrogen receptor
Authors:	Fanning, S.W, Greene, G.L.
Deposit date:	2022-03-30
Release date:	2022-05-04
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.68 Å)
Cite:	Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife, 11, 2022

Crystal Structure of the Monobody ySMB-1 bound to yeast SUMO
Descriptor:	GLYCEROL, Monobody ySMB-1, Ubiquitin-like protein SMT3
Authors:	Koide, S, Gilbreth, R.N.
Deposit date:	2011-01-26
Release date:	2011-05-11
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library design. Proc.Natl.Acad.Sci.USA, 108, 2011