7ND8
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![BU of 7nd8 by Molmil](/molmil-images/mine/7nd8) | EM structure of SARS-CoV-2 Spike glycoprotein in complex with COVOX-384 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COVOX-384 Fab heavy chain, ... | Authors: | Duyvesteyn, H.M.E, Zhao, Y, Ren, J, Stuart, D. | Deposit date: | 2021-01-30 | Release date: | 2021-03-03 | Last modified: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The antigenic anatomy of SARS-CoV-2 receptor binding domain. Cell, 184, 2021
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7NDC
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![BU of 7ndc by Molmil](/molmil-images/mine/7ndc) | EM structure of SARS-CoV-2 Spike glycoprotein (all RBD down) in complex with COVOX-159 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COVOX-159 Fab light chain, ... | Authors: | Duyvesteyn, H.M.E, Zhao, Y, Ren, J, Stuart, D. | Deposit date: | 2021-01-30 | Release date: | 2021-03-03 | Last modified: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | The antigenic anatomy of SARS-CoV-2 receptor binding domain. Cell, 184, 2021
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7ND9
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![BU of 7nd9 by Molmil](/molmil-images/mine/7nd9) | EM structure of SARS-CoV-2 Spike glycoprotein (one RBD up) in complex with COVOX-253H55L Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Duyvesteyn, H.M.E, Zhao, Y, Ren, J, Stuart, D. | Deposit date: | 2021-01-30 | Release date: | 2021-03-03 | Last modified: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | The antigenic anatomy of SARS-CoV-2 receptor binding domain. Cell, 184, 2021
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7ZR9
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![BU of 7zr9 by Molmil](/molmil-images/mine/7zr9) | OMI-2 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE GLYCOPROTEIN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Omi-2 Fab heavy chain, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | Deposit date: | 2022-05-03 | Release date: | 2022-06-01 | Last modified: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Potent cross-reactive antibodies following Omicron breakthrough in vaccinees. Cell, 185, 2022
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7ZR8
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![BU of 7zr8 by Molmil](/molmil-images/mine/7zr8) | OMI-38 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE RBD (local refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Omi-38 Fab light chain, Omi-38 fab heavy chain, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | Deposit date: | 2022-05-03 | Release date: | 2022-06-01 | Last modified: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Potent cross-reactive antibodies following Omicron breakthrough in vaccinees. Cell, 185, 2022
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7ZRC
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![BU of 7zrc by Molmil](/molmil-images/mine/7zrc) | OMI-38 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Omi-38 Fab Heavy Chain, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | Deposit date: | 2022-05-04 | Release date: | 2022-06-01 | Last modified: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Potent cross-reactive antibodies following Omicron breakthrough in vaccinees. Cell, 185, 2022
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7ZR7
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![BU of 7zr7 by Molmil](/molmil-images/mine/7zr7) | OMI-42 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE GLYCOPROTEIN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Omi-42 heavy chain, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | Deposit date: | 2022-05-03 | Release date: | 2022-06-01 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Potent cross-reactive antibodies following Omicron breakthrough in vaccinees. Cell, 185, 2022
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8A8N
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![BU of 8a8n by Molmil](/molmil-images/mine/8a8n) | |
8BCZ
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![BU of 8bcz by Molmil](/molmil-images/mine/8bcz) | SARS-CoV-2 Delta-RBD complexed with Fabs BA.2-36, BA.2-23, EY6A and COVOX-45 | Descriptor: | BA.2-23 heavy chain, BA.2-23 light chain, BA.2-36 heavy chain, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | Deposit date: | 2022-10-17 | Release date: | 2023-03-22 | Last modified: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Rapid escape of new SARS-CoV-2 Omicron variants from BA.2-directed antibody responses. Cell Rep, 42, 2023
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7Q0A
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![BU of 7q0a by Molmil](/molmil-images/mine/7q0a) | SARS-CoV-2 Spike ectodomain with Fab FI3A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FI3A fab Light chain, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | Deposit date: | 2021-10-14 | Release date: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2. Theranostics, 12, 2022
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7Q9F
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![BU of 7q9f by Molmil](/molmil-images/mine/7q9f) | Beta-50 fab in complex with SARS-CoV-2 beta-Spike glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | Deposit date: | 2021-11-12 | Release date: | 2021-12-15 | Last modified: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
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7Q9G
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![BU of 7q9g by Molmil](/molmil-images/mine/7q9g) | COVOX-222 fab in complex with SARS-CoV-2 beta-Spike glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COVOX-222 heavy chain, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | Deposit date: | 2021-11-12 | Release date: | 2021-12-15 | Last modified: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
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7Q9J
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![BU of 7q9j by Molmil](/molmil-images/mine/7q9j) | Beta-26 fab in complex with SARS-CoV-2 beta-Spike glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-26 heavy chain, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | Deposit date: | 2021-11-12 | Release date: | 2021-12-15 | Last modified: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
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7Q6E
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![BU of 7q6e by Molmil](/molmil-images/mine/7q6e) | Beta049 fab in complex with SARS-CoV2 beta-Spike glycoprotein, The Beta mAb response underscores the antigenic distance to other SARS-CoV-2 variants | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-49 heavy chain, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | Deposit date: | 2021-11-07 | Release date: | 2021-12-15 | Last modified: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
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7Q9K
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![BU of 7q9k by Molmil](/molmil-images/mine/7q9k) | Beta-32 fab in complex with SARS-CoV-2 beta-Spike glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-32 heavy chain, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | Deposit date: | 2021-11-12 | Release date: | 2021-12-15 | Last modified: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
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7Q9M
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![BU of 7q9m by Molmil](/molmil-images/mine/7q9m) | Beta-53 fab in complex with SARS-CoV-2 beta-Spike glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-53 fab heavy chain, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | Deposit date: | 2021-11-12 | Release date: | 2021-12-15 | Last modified: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
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7Q9I
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![BU of 7q9i by Molmil](/molmil-images/mine/7q9i) | Beta-43 fab in complex with SARS-CoV-2 beta-Spike glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-43 heavy chain, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | Deposit date: | 2021-11-12 | Release date: | 2021-12-15 | Last modified: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
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7Q9P
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![BU of 7q9p by Molmil](/molmil-images/mine/7q9p) | Beta-06 fab in complex with SARS-CoV-2 beta-Spike glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-06 heavy chain, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | Deposit date: | 2021-11-12 | Release date: | 2021-12-15 | Last modified: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
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6QWG
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![BU of 6qwg by Molmil](/molmil-images/mine/6qwg) | Serial Femtosecond Crystallography Structure of Cu Nitrite Reductase from Achromobacter cycloclastes: Nitrite complex at Room Temperature | Descriptor: | COPPER (II) ION, Copper-containing nitrite reductase, NITRITE ION | Authors: | Ebrahim, A.E, Moreno-Chicano, T, Appleby, M.V, Worrall, J.W, Duyvesteyn, H.M.E, Strange, R.W, Beale, J, Axford, D, Sherrell, D.A, Sugimoto, H, Owada, S, Tono, K, Owen, R.L. | Deposit date: | 2019-03-05 | Release date: | 2019-11-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High-throughput structures of protein-ligand complexes at room temperature using serial femtosecond crystallography. Iucrj, 6, 2019
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8QSQ
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![BU of 8qsq by Molmil](/molmil-images/mine/8qsq) | |
8QTD
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![BU of 8qtd by Molmil](/molmil-images/mine/8qtd) | Local refinement of SARS-CoV-2 BA.2.86 Spike and XBB-7 Fab | Descriptor: | Spike glycoprotein,Fibritin, XBB-7 fab heavy chain, XBB-7 fab light chain | Authors: | Ren, J, Duyvesteyn, H.M.E, Stuart, D.I. | Deposit date: | 2023-10-12 | Release date: | 2024-05-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity. Cell Rep Med, 5, 2024
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6YOR
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![BU of 6yor by Molmil](/molmil-images/mine/6yor) | Structure of the SARS-CoV-2 spike S1 protein in complex with CR3022 Fab | Descriptor: | IgG H chain, IgG L chain, Spike glycoprotein | Authors: | Huo, J, Zhao, Y, Ren, J, Zhou, D, Duyvesteyn, H.M.E, Carrique, L, Malinauskas, T, Ruza, R.R, Shah, P.N.M, Fry, E.E, Owens, R, Stuart, D.I. | Deposit date: | 2020-04-15 | Release date: | 2020-04-29 | Last modified: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike. Cell Host Microbe, 28, 2020
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6Z43
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![BU of 6z43 by Molmil](/molmil-images/mine/6z43) | Cryo-EM Structure of SARS-CoV-2 Spike : H11-D4 Nanobody Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody, ... | Authors: | Ruza, R.R, Duyvesteyn, H.M.E, Shah, P, Carrique, L, Ren, J, Malinauskas, T, Zhou, D, Stuart, D.I, Naismith, J.H. | Deposit date: | 2020-05-22 | Release date: | 2020-06-03 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for a potent neutralising single-domain antibody that blocks SARS-CoV-2 binding to its receptor ACE2 To Be Published
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6I43
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![BU of 6i43 by Molmil](/molmil-images/mine/6i43) | SFX Structure of Damage Free Ferric State of Dye Type Peroxidase Aa from Streptomyces lividans | Descriptor: | Deferrochelatase/peroxidase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Ebrahim, A, Moreno-Chicano, T, Chaplin, A.K, Sherrell, D.A, Duyvesteyn, H.M.E, Owada, S, Tono, K, Sugimoto, H, Strange, R.W, Worrall, J.A.R. | Deposit date: | 2018-11-08 | Release date: | 2019-09-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Dose-resolved serial synchrotron and XFEL structures of radiation-sensitive metalloproteins. Iucrj, 6, 2019
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7QNY
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![BU of 7qny by Molmil](/molmil-images/mine/7qny) | The receptor binding domain of SARS-CoV-2 spike glycoprotein in complex with COVOX-58 and COVOX-158 Fabs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COVOX-158 heavy chain, COVOX-158 light chain, ... | Authors: | Zhou, D, Ren, J, Stuart, D.I. | Deposit date: | 2021-12-23 | Release date: | 2022-01-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses. Cell, 185, 2022
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