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Human Adenosine Deaminase Acting on dsRNA (ADAR2) mutant E488Q bound to dsRNA sequence derived from human GLI1 gene
Descriptor:	Double-stranded RNA-specific editase 1, INOSITOL HEXAKISPHOSPHATE, RNA (5'-R(PCPAPGPAPGPCPCPCPCPCPCPAPGPCPAPUPCPGPCPGPAPGP*C)-3'), ...
Authors:	Matthews, M.M, Fisher, A.J.
Deposit date:	2015-10-20
Release date:	2016-04-13
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.95 Å)
Cite:	Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity. Nat.Struct.Mol.Biol., 23, 2016

Structure of the SpCas9 DNA adenine base editor - ABE8e
Descriptor:	CRISPR-associated endonuclease Cas9, Cas9 (SpCas9) single-guide RNA (sgRNA), DNA non-target strand (NTS), ...
Authors:	Knott, G.J, Lapinaite, A, Doudna, J.A.
Deposit date:	2020-02-03
Release date:	2020-07-29
Last modified:	2024-03-06
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	DNA capture by a CRISPR-Cas9-guided adenine base editor. Science, 369, 2020

Human Argonaute-2 bound to a guide RNA with a nucleobase modification at position 1
Descriptor:	PHENOL, Protein argonaute-2, miR-122
Authors:	Schirle, N.T, MacRae, I.J.
Deposit date:	2016-06-16
Release date:	2016-07-20
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.153 Å)
Cite:	Structure-Guided Control of siRNA Off-Target Effects. J.Am.Chem.Soc., 138, 2016